| Reaction Details |
|---|
 | Report a problem with these data |
| Target | RmtA |
|---|
| Ligand | BDBM50215479 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_439623 (CHEMBL888739) |
|---|
| IC50 | 46200±n/a nM |
|---|
| Citation |  Spannhoff, A; Machmur, R; Heinke, R; Trojer, P; Bauer, I; Brosch, G; Schüle, R; Hanefeld, W; Sippl, W; Jung, M A novel arginine methyltransferase inhibitor with cellular activity. Bioorg Med Chem Lett17:4150-3 (2007) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| RmtA |
|---|
| Name: | RmtA |
|---|
| Synonyms: | n/a |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 39351.26 |
|---|
| Organism: | Emericella nidulans |
|---|
| Description: | ChEMBL_475539 |
|---|
| Residue: | 345 |
|---|
| Sequence: | MSEIENSTITSSADRMVGMDHAEVRYFTSYDHHGIHEEMLKDDVRTRSYRDSIYQNRHIF
KDKVVLDVGCGTGILSMFAAKAGAKHVIGVDMSSIIEKAREIVAVNGLADKITLLQGKME
EVQLPFPSVDIIISEWMGYFLLYESMLDTVLYAQDRYLVPGGKIFPDKATMYLAGIEDGE
YKDDKIGFWDNVYGFDYSPMKEIALTEPLVDTVELKALVTDPCPIITFDLYTVTKEDLAF
EVPYSLPVKRSDFVHAVIAWFDIEFGACHKPINFSTGPHAKYTHWKQTVFYLRDVLTVEE
EESISGVLSNRPNDKNKRDLDINLTYKLETQDQTRFAEGGCFYRM
|
|
|
|---|
| BDBM50215479 |
|---|
| n/a |
|---|
| Name | BDBM50215479 |
|---|
| Synonyms: | 2-(9H-xanthen-9-ylsulfanyl)-N-{2-[2-(9H-xanthen-9-ylsulfanyl)-propionylamino]-ethyl}-propionamide | CHEMBL61824 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C34H32N2O4S2 |
|---|
| Mol. Mass. | 596.759 |
|---|
| SMILES | CC(SC1c2ccccc2Oc2ccccc12)C(=O)NCCNC(=O)C(C)SC1c2ccccc2Oc2ccccc12 |w:25.28,1.0| |
|---|
| Structure | 
|
|---|
Search and Browse
