| Reaction Details |
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 | Report a problem with these data |
| Target | Nuclear receptor subfamily 4 group A member 2 |
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| Ligand | BDBM50196289 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_453027 (CHEMBL902174) |
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| EC50 | 4.1±n/a nM |
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| Citation |  Hintermann, S; Chiesi, M; von Krosigk, U; Mathé, D; Felber, R; Hengerer, B Identification of a series of highly potent activators of the Nurr1 signaling pathway. Bioorg Med Chem Lett17:193-6 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Nuclear receptor subfamily 4 group A member 2 |
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| Name: | Nuclear receptor subfamily 4 group A member 2 |
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| Synonyms: | NOT | NR4A2 | NR4A2_HUMAN | NURR1 | TINUR |
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| Type: | PROTEIN |
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| Mol. Mass.: | 66603.77 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_453027 |
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| Residue: | 598 |
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| Sequence: | MPCVQAQYGSSPQGASPASQSYSYHSSGEYSSDFLTPEFVKFSMDLTNTEITATTSLPSF
STFMDNYSTGYDVKPPCLYQMPLSGQQSSIKVEDIQMHNYQQHSHLPPQSEEMMPHSGSV
YYKPSSPPTPTTPGFQVQHSPMWDDPGSLHNFHQNYVATTHMIEQRKTPVSRLSLFSFKQ
SPPGTPVSSCQMRFDGPLHVPMNPEPAGSHHVVDGQTFAVPNPIRKPASMGFPGLQIGHA
SQLLDTQVPSPPSRGSPSNEGLCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCL
ANKNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKSPQEPSPPSP
PVSLISALVRAHVDSNPAMTSLDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGW
AEKIPGFADLPKADQDLLFESAFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQCVRGFG
EWIDSIVEFSSNLQNMNIDISAFSCIAALAMVTERHGLKEPKRVEELQNKIVNCLKDHVT
FNNGGLNRPNYLSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTLPF
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| BDBM50196289 |
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| n/a |
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| Name | BDBM50196289 |
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| Synonyms: | 6-(4-methoxyphenyl)-5-methyl-3-phenylisoxazolo[4,5-c]pyridin-4(5H)-one | CHEMBL399602 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H16N2O3 |
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| Mol. Mass. | 332.3526 |
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| SMILES | COc1ccc(cc1)-c1cc2onc(-c3ccccc3)c2c(=O)n1C |
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| Structure | 
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