| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 5A |
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| Ligand | BDBM50371974 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_464404 (CHEMBL930054) |
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| Ki | 5.7±n/a nM |
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| Citation |  Peters, JU; Lübbers, T; Alanine, A; Kolczewski, S; Blasco, F; Steward, L Cyclic guanidines as dual 5-HT5A/5-HT7 receptor ligands: optimising brain penetration. Bioorg Med Chem Lett18:262-6 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 5A |
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| Name: | 5-hydroxytryptamine receptor 5A |
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| Synonyms: | 5-HT-5 | 5-HT-5A | 5-hydroxytryptamine receptor 5 (5-HT5) | 5-hydroxytryptamine receptor 5A (5-HT5A) | 5HT5A_HUMAN | HTR5A | Serotonin (5-HT) receptor | Serotonin receptor 5A |
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| Type: | Enzyme |
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| Mol. Mass.: | 40266.25 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P47898 |
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| Residue: | 357 |
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| Sequence: | MDLPVNLTSFSLSTPSPLETNHSLGKDDLRPSSPLLSVFGVLILTLLGFLVAATFAWNLL
VLATILRVRTFHRVPHNLVASMAVSDVLVAALVMPLSLVHELSGRRWQLGRRLCQLWIAC
DVLCCTASIWNVTAIALDRYWSITRHMEYTLRTRKCVSNVMIALTWALSAVISLAPLLFG
WGETYSEGSEECQVSREPSYAVFSTVGAFYLPLCVVLFVYWKIYKAAKFRVGSRKTNSVS
PISEAVEVKDSAKQPQMVFTVRHATVTFQPEGDTWREQKEQRAALMVGILIGVFVLCWIP
FFLTELISPLCSCDIPAIWKSIFLWLGYSNSFFNPLIYTAFNKNYNSAFKNFFSRQH
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| BDBM50371974 |
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| n/a |
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| Name | BDBM50371974 |
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| Synonyms: | CHEMBL256047 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H11Cl2F2N3 |
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| Mol. Mass. | 294.128 |
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| SMILES | C[C@H]1NC(NCC(F)F)=Nc2ccc(Cl)c(Cl)c12 |c:8| |
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| Structure | 
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