| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 5A |
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| Ligand | BDBM50371998 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_464428 (CHEMBL930101) |
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| Ki | 1.3±n/a nM |
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| Citation |  Peters, JU; Lübbers, T; Alanine, A; Kolczewski, S; Blasco, F; Steward, L Cyclic guanidines as dual 5-HT5A/5-HT7 receptor ligands: optimising brain penetration. Bioorg Med Chem Lett18:262-6 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 5A |
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| Name: | 5-hydroxytryptamine receptor 5A |
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| Synonyms: | 5-HT-5A | 5-HT5a | 5-hydroxytryptamine receptor 5A | 5HT5A_RAT | 5ht5a | Htr5a | REC17 | Serotonin (5-HT) receptor | Serotonin receptor 5A |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 40684.21 |
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| Organism: | RAT |
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| Description: | 5-HT5a HTR5A RAT::P35364 |
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| Residue: | 357 |
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| Sequence: | MDLPINLTSFSLSTPSTLEPNRSLDTEALRTSQSFLSAFRVLVLTLLGFLAAATFTWNLL
VLATILRVRTFHRVPHNLVASMAISDVLVAVLVMPLSLVHELSGRRWQLGRRLCQLWIAC
DVLCCTASIWNVTAIALDRYWSITRHLEYTLRARKRVSNVMILLTWALSAVISLAPLLFG
WGETYSELSEECQVSREPSYTVFSTVGAFYLPLCVVLFVYWKIYKAAKFRMGSRKTNSVS
PIPEAVEVKDASQHPQMVFTVRHATVTFQTEGDTWREQKEQRAALMVGILIGVFVLCWFP
FFVTELISPLCSWDIPALWKSIFLWLGYSNSFFNPLIYTAFNRSYSSAFKVFFSKQQ
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| BDBM50371998 |
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| n/a |
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| Name | BDBM50371998 |
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| Synonyms: | CHEMBL404372 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H10ClN3 |
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| Mol. Mass. | 195.649 |
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| SMILES | C[C@@H]1NC(N)=Nc2cccc(Cl)c12 |c:4| |
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| Structure | 
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