| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosylhomocysteinase |
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| Ligand | BDBM50373102 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_466720 (CHEMBL937441) |
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| IC50 | 90700±n/a nM |
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| Citation |  Ando, T; Iwata, M; Zulfiqar, F; Miyamoto, T; Nakanishi, M; Kitade, Y Synthesis of 2-modified aristeromycins and their analogs as potent inhibitors against Plasmodium falciparum S-adenosyl-L-homocysteine hydrolase. Bioorg Med Chem16:3809-15 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosylhomocysteinase |
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| Name: | Adenosylhomocysteinase |
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| Synonyms: | AHCY | Adenosylhomocysteinase | SAHH | SAHH_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 47714.06 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1507791 |
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| Residue: | 432 |
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| Sequence: | MSDKLPYKVADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVET
AVLIETLVTLGAEVQWSSCNIFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYF
KDGPLNMILDDGGDLTNLIHTKYPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINV
NDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVI
ITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIG
HFDVEIDVKWLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGHPSFVMSN
SFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMS
CDGPFKPDHYRY
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| BDBM50373102 |
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| n/a |
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| Name | BDBM50373102 |
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| Synonyms: | CHEMBL261619 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H16N6O3 |
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| Mol. Mass. | 280.2831 |
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| SMILES | Nc1nc(N)c2ncn([C@@H]3C[C@H](CO)[C@@H](O)[C@H]3O)c2n1 |
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| Structure | 
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