| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosylhomocysteinase |
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| Ligand | BDBM50373100 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_466721 (CHEMBL937442) |
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| IC50 | 2100±n/a nM |
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| Citation |  Ando, T; Iwata, M; Zulfiqar, F; Miyamoto, T; Nakanishi, M; Kitade, Y Synthesis of 2-modified aristeromycins and their analogs as potent inhibitors against Plasmodium falciparum S-adenosyl-L-homocysteine hydrolase. Bioorg Med Chem16:3809-15 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosylhomocysteinase |
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| Name: | Adenosylhomocysteinase |
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| Synonyms: | AdoHcyase | PfSAHH | S-adenosyl-L-homocysteine hydrolase | SAHH_PLAF7 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 53833.80 |
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| Organism: | Plasmodium falciparum 3D7 |
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| Description: | ChEMBL_196715 |
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| Residue: | 479 |
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| Sequence: | MVENKSKVKDISLAPFGKMQMEISENEMPGLMRIREEYGKDQPLKNAKITGCLHMTVECA
LLIETLQKLGAQIRWCSCNIYSTADYAAAAVSTLENVTVFAWKNETLEEYWWCVESALTW
GDGDDNGPDMIVDDGGDATLLVHKGVEYEKLYEEKNILPDPEKAKNEEERCFLTLLKNSI
LKNPKKWTNIAKKIIGVSEETTTGVLRLKKMDKQNELLFTAINVNDAVTKQKYDNVYGCR
HSLPDGLMRATDFLISGKIVVICGYGDVGKGCASSMKGLGARVYITEIDPICAIQAVMEG
FNVVTLDEIVDKGDFFITCTGNVDVIKLEHLLKMKNNAVVGNIGHFDDEIQVNELFNYKG
IHIENVKPQVDRITLPNGNKIIVLARGRLLNLGCATGHPAFVMSFSFCNQTFAQLDLWQN
KDTNKYENKVYLLPKHLDEKVALYHLKKLNASLTELDDNQCQFLGVNKSGPFKSNEYRY
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| BDBM50373100 |
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| n/a |
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| Name | BDBM50373100 |
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| Synonyms: | CHEMBL262063 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H15N5O3 |
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| Mol. Mass. | 277.2792 |
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| SMILES | Nc1ncnc2n(cnc12)[C@H]1[C@H](O)[C@H](O)[C@@H](CO)C1=C |
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| Structure | 
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