Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Neuropeptide Y receptor type 5 | ||
| Ligand | BDBM50373625 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_468024 (CHEMBL948247) | ||
| Ki | 1.5±n/a nM | ||
| Citation |  Li, G; Stamford, AW; Huang, Y; Cheng, KC; Cook, J; Farley, C; Gao, J; Ghibaudi, L; Greenlee, WJ; Guzzi, M; van Heek, M; Hwa, JJ; Kelly, J; Mullins, D; Parker, EM; Wainhaus, S; Zhang, X Discovery of novel orally active ureido NPY Y5 receptor antagonists. Bioorg Med Chem Lett18:1146-50 (2008) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Neuropeptide Y receptor type 5 | |||
| Name: | Neuropeptide Y receptor type 5 | ||
| Synonyms: | NPY-Y5 | NPY-Y5 receptor | NPY5-R | NPY5R | NPY5R_HUMAN | NPYR5 | NPYY5 | Neuropeptide Y receptor type 5 | Neuropeptide Y receptor type 5 ( NPY Y5) | Y5 receptor | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 50746.64 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q15761 | ||
| Residue: | 445 | ||
| Sequence: |
| ||
| BDBM50373625 | |||
| n/a | |||
| Name | BDBM50373625 | ||
| Synonyms: | CHEMBL403918 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H31F2N3O2 | ||
| Mol. Mass. | 407.4972 | ||
| SMILES | CCC(=O)N1CCC(CC1)N(C)C(=O)N[C@H]1CC[C@@H](CC1)c1cc(F)cc(F)c1 |wU:15.15,wD:18.22,(36.07,-39.93,;34.73,-39.16,;33.4,-39.92,;33.39,-41.46,;32.07,-39.15,;30.73,-39.91,;29.4,-39.14,;29.42,-37.61,;30.74,-36.83,;32.07,-37.6,;28.08,-36.84,;28.08,-35.3,;26.75,-37.61,;26.75,-39.15,;25.41,-36.84,;24.08,-37.61,;24.08,-39.14,;22.74,-39.91,;21.41,-39.14,;21.42,-37.59,;22.75,-36.83,;20.07,-39.9,;20.07,-41.43,;18.74,-42.2,;18.74,-43.74,;17.4,-41.43,;17.41,-39.88,;16.08,-39.11,;18.74,-39.12,)| | ||
| Structure | 
| ||