| Reaction Details |
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 | Report a problem with these data |
| Target | Melanocyte-stimulating hormone receptor |
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| Ligand | BDBM50374125 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_468951 (CHEMBL951290) |
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| EC50 | 3400±n/a nM |
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| Citation |  Joseph, CG; Wilson, KR; Wood, MS; Sorenson, NB; Phan, DV; Xiang, Z; Witek, RM; Haskell-Luevano, C The 1,4-benzodiazepine-2,5-dione small molecule template results in melanocortin receptor agonists with nanomolar potencies. J Med Chem51:1423-31 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Melanocyte-stimulating hormone receptor |
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| Name: | Melanocyte-stimulating hormone receptor |
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| Synonyms: | MC1-R | MSHR_MOUSE | Mc1r | Melanocortin receptor 1 | Melanocyte-stimulating hormone receptor | Msh-r |
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| Type: | PROTEIN |
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| Mol. Mass.: | 35238.60 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1498846 |
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| Residue: | 315 |
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| Sequence: | MSTQEPQKSLLGSLNSNATSHLGLATNQSEPWCLYVSIPDGLFLSLGLVSLVENVLVVIA
ITKNRNLHSPMYYFICCLALSDLMVSVSIVLETTIILLLEAGILVARVALVQQLDNLIDV
LICGSMVSSLCFLGIIAIDRYISIFYALRYHSIVTLPRARRAVVGIWMVSIVSSTLFITY
YKHTAVLLCLVTFFLAMLALMAILYAHMFTRACQHAQGIAQLHKRRRSIRQGFCLKGAAT
LTILLGIFFLCWGPFFLHLLLIVLCPQHPTCSCIFKNFNLFLLLIVLSSTVDPLIYAFRS
QELRMTLKEVLLCSW
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| BDBM50374125 |
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| n/a |
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| Name | BDBM50374125 |
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| Synonyms: | CHEMBL409222 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H24ClN3O2 |
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| Mol. Mass. | 421.919 |
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| SMILES | NCCCCC1NC(=O)c2ccc(Cl)cc2N(Cc2ccc3ccccc3c2)C1=O |w:5.4| |
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| Structure | 
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