| Reaction Details |
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 | Report a problem with these data |
| Target | Melanocortin receptor 5 |
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| Ligand | BDBM50374122 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_468954 (CHEMBL951293) |
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| EC50 | 3267±n/a nM |
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| Citation |  Joseph, CG; Wilson, KR; Wood, MS; Sorenson, NB; Phan, DV; Xiang, Z; Witek, RM; Haskell-Luevano, C The 1,4-benzodiazepine-2,5-dione small molecule template results in melanocortin receptor agonists with nanomolar potencies. J Med Chem51:1423-31 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Melanocortin receptor 5 |
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| Name: | Melanocortin receptor 5 |
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| Synonyms: | MC5R_MOUSE | Mc5r | Melanocortin receptor 5 | Melanocortin receptor 5 (MC5R) |
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| Type: | Enzyme |
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| Mol. Mass.: | 36966.58 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | P41149 |
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| Residue: | 325 |
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| Sequence: | MNSSSTLTVLNLTLNASEDGILGSNVKNKSLACEEMGIAVEVFLTLGLVSLLENILVIGA
IVKNKNLHSPMYFFVGSLAVADMLVSMSNAWETVTIYLLNNKHLVIADTFVRHIDNVFDS
MICISVVASMCSLLAIAVDRYITIFYALRYHHIMTARRSGVIIACIWTFCISCGIVFIIY
YESKYVIICLISMFFTMLFFMVSLYIHMFLLARNHVKRIAASPRYNSVRQRTSMKGAITL
TMLLGIFIVCWSPFFLHLILMISCPQNVYCSCFMSYFNMYLILIMCNSVIDPLIYALRSQ
EMRRTFKEIVCCHGFRRPCRLLGGY
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| BDBM50374122 |
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| n/a |
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| Name | BDBM50374122 |
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| Synonyms: | CHEMBL269837 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H20N2O2 |
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| Mol. Mass. | 308.3743 |
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| SMILES | CCCN1c2ccccc2C(=O)NC(Cc2ccccc2)C1=O |w:13.14| |
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| Structure | 
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