| Reaction Details |
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 | Report a problem with these data |
| Target | DNA polymerase beta |
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| Ligand | BDBM50375300 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_470719 (CHEMBL934559) |
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| IC50 | 16300±n/a nM |
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| Citation |  Naganuma, M; Nishida, M; Kuramochi, K; Sugawara, F; Yoshida, H; Mizushina, Y 1-deoxyrubralactone, a novel specific inhibitor of families X and Y of eukaryotic DNA polymerases from a fungal strain derived from sea algae. Bioorg Med Chem16:2939-44 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| DNA polymerase beta |
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| Name: | DNA polymerase beta |
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| Synonyms: | DNA Polymerase beta | DPOLB_RAT | Polb |
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| Type: | PROTEIN |
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| Mol. Mass.: | 38334.34 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1361926 |
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| Residue: | 335 |
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| Sequence: | MSKRKAPQETLNGGITDMLVELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAK
KLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVTGIGPSAARKLVDEGIK
TLEDLRKNEDKLNHHQRIGLKYFEDFEKRIPREEMLQMQDIVLNEVKKLDPEYIATVCGS
FRRGAESSGDMDVLLTHPNFTSESSKQPKLLHRVVEQLQKVRFITDTLSKGETKFMGVCQ
LPSENDENEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRP
LGVTGVAGEPLPVDSEQDIFDYIQWRYREPKDRSE
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| BDBM50375300 |
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| n/a |
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| Name | BDBM50375300 |
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| Synonyms: | TALAROFLAVONE |
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| Type | Small organic molecule |
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| Emp. Form. | C14H12O6 |
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| Mol. Mass. | 276.2415 |
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| SMILES | COc1cc2c(C(=O)OC22C(C)CC(=O)C2=O)c(O)c1 |
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| Structure | 
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