| Reaction Details |
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 | Report a problem with these data |
| Target | Thromboxane A2 receptor |
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| Ligand | BDBM50376304 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_475967 (CHEMBL935622) |
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| Ki | 11.7±n/a nM |
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| Citation |  Beaulieu, C; Guay, D; Wang, Z; Leblanc, Y; Roy, P; Dufresne, C; Zamboni, R; Berthelette, C; Day, S; Tsou, N; Denis, D; Greig, G; Mathieu, MC; O'Neill, G Identification of prostaglandin D2 receptor antagonists based on a tetrahydropyridoindole scaffold. Bioorg Med Chem Lett18:2696-700 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Thromboxane A2 receptor |
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| Name: | Thromboxane A2 receptor |
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| Synonyms: | Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta |
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| Type: | Enyzme |
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| Mol. Mass.: | 37445.28 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21731 |
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| Residue: | 343 |
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| Sequence: | MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTR
SSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPL
LLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPG
SWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSE
VEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWN
QILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
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| BDBM50376304 |
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| n/a |
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| Name | BDBM50376304 |
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| Synonyms: | CHEMBL261501 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H19ClFNO4S |
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| Mol. Mass. | 435.896 |
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| SMILES | CS(=O)(=O)c1cc(F)cc2n3CCC(CC(O)=O)c3c(Cc3ccc(Cl)cc3)c12 |w:13.13| |
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| Structure | 
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