| Reaction Details |
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 | Report a problem with these data |
| Target | Aspartate-semialdehyde dehydrogenase |
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| Ligand | BDBM50377941 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_550047 (CHEMBL1003381) |
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| IC50 | 306000±n/a nM |
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| Citation |  Carroll, AR; Ngo, A; Quinn, RJ; Redburn, J; Hooper, JN Petrosamine B, an inhibitor of the Helicobacter pylori enzyme aspartyl semialdehyde dehydrogenase from the Australian sponge Oceanapia sp. J Nat Prod68:804-6 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Aspartate-semialdehyde dehydrogenase |
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| Name: | Aspartate-semialdehyde dehydrogenase |
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| Synonyms: | DHAS_HELPY | asd |
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| Type: | PROTEIN |
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| Mol. Mass.: | 38120.98 |
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| Organism: | Helicobacter pylori |
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| Description: | ChEMBL_550047 |
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| Residue: | 346 |
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| Sequence: | MKTYNVAIVGASGAVGQELIKGLENSFFPIKKFVPLASTRSAGKKIKAFNKDYEILETTH
EVFEREKIDIAFFSAGGSVSEEFATSASKTALVVDNTSFFRLNKDVPLVVPEINAKEIFN
APLNIIANPNCSTIQMTQILNPLHLHFKIKSVIVSTYQAVSGAGNKGIESLKNELKTALE
CLEKDPTIDLNQVLQAGAFAYPIAFNAIAHIDTFKENGYTKEELKMLHETHKIMGVDFPI
SATCVRVPVLRSHSESLSIAFEKEFDLKEVYEVLKNAPSVAVCDDPSHNLYPTPLKASHT
DSVFIGRLRKDLFDKKTLHGFCVADQLRVGAATNALKIALHYIKNA
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| BDBM50377941 |
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| n/a |
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| Name | BDBM50377941 |
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| Synonyms: | PETROSAMINE B |
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| Type | Small organic molecule |
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| Emp. Form. | C21H18BrN3O2 |
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| Mol. Mass. | 424.289 |
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| SMILES | Cn1ccc2c(c1)c(=[OH+])c1c3c(C(=O)C[N+]1(C)C)c1cc(Br)ccc1nc23 |
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| Structure | 
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