| Reaction Details |
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 | Report a problem with these data |
| Target | Neutral cholesterol ester hydrolase 1 |
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| Ligand | BDBM50161512 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_513867 (CHEMBL970761) |
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| IC50 | 90000±n/a nM |
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| Citation |  Garfunkle, J; Ezzili, C; Rayl, TJ; Hochstatter, DG; Hwang, I; Boger, DL Optimization of the central heterocycle of alpha-ketoheterocycle inhibitors of fatty acid amide hydrolase. J Med Chem51:4392-403 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neutral cholesterol ester hydrolase 1 |
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| Name: | Neutral cholesterol ester hydrolase 1 |
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| Synonyms: | AADACL1 | KIAA1363 | NCEH1 | NCEH1_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 45810.81 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_835312 |
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| Residue: | 408 |
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| Sequence: | MRSSCVLLTALVALAAYYVYIPLPGSVSDPWKLMLLDATFRGAQQVSNLIHYLGLSHHLL
ALNFIIVSFGKKSAWSSAQVKVTDTDFDGVEVRVFEGPPKPEEPLKRSVVYIHGGGWALA
SAKIRYYDELCTAMAEELNAVIVSIEYRLVPKVYFPEQIHDVVRATKYFLKPEVLQKYMV
DPGRICISGDSAGGNLAAALGQQFTQDASLKNKLKLQALIYPVLQALDFNTPSYQQNVNT
PILPRYVMVKYWVDYFKGNYDFVQAMIVNNHTSLDVEEAAAVRARLNWTSLLPASFTKNY
KPVVQTTGNARIVQELPQLLDARSAPLIADQAVLQLLPKTYILTCEHDVLRDDGIMYAKR
LESAGVEVTLDHFEDGFHGCMIFTSWPTNFSVGIRTRNSYIKWLDQNL
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| BDBM50161512 |
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| n/a |
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| Name | BDBM50161512 |
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| Synonyms: | 7-Phenyl-1-(5-(pyridin-2-yl)-1,3,4-oxadiazol-2-yl)-heptan-1-one | 7-Phenyl-1-(5-pyridin-2-yl-[1,3,4]oxadiazol-2-yl)-heptan-1-one | 7-phenyl-1-(5-(pyridin-2-yl)-1,3,4-oxadiazol-2-yl)heptan-1-one | CHEMBL178398 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H21N3O2 |
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| Mol. Mass. | 335.3996 |
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| SMILES | O=C(CCCCCCc1ccccc1)c1nnc(o1)-c1ccccn1 |
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| Structure | 
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