Found 569 hits with Last Name = 'ezzili' and Initial = 'c' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50228837
(2-(3-(biphenyl-4-yl)propanoyl)oxazole-5-carbonitri...)Show InChI InChI=1S/C19H14N2O2/c20-12-17-13-21-19(23-17)18(22)11-8-14-6-9-16(10-7-14)15-4-2-1-3-5-15/h1-7,9-10,13H,8,11H2 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant FAAH expressed in Escherichia coli |
J Med Chem 51: 937-47 (2008)
Article DOI: 10.1021/jm701210y BindingDB Entry DOI: 10.7270/Q2QV3NCP |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50161518
(1-(oxazolo[4,5-b]pyridin-2-yl)-6-phenylhexan-1-one...)Show InChI InChI=1S/C18H18N2O2/c21-15(18-20-17-16(22-18)12-7-13-19-17)11-6-2-5-10-14-8-3-1-4-9-14/h1,3-4,7-9,12-13H,2,5-6,10-11H2 | PDB
UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of FAAH |
Bioorg Med Chem Lett 21: 4674-85 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.096 BindingDB Entry DOI: 10.7270/Q2W959JK |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50228837
(2-(3-(biphenyl-4-yl)propanoyl)oxazole-5-carbonitri...)Show InChI InChI=1S/C19H14N2O2/c20-12-17-13-21-19(23-17)18(22)11-8-14-6-9-16(10-7-14)15-4-2-1-3-5-15/h1-7,9-10,13H,8,11H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.260 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of human recombinant FAAH expressed COS7 cells |
J Med Chem 51: 937-47 (2008)
Article DOI: 10.1021/jm701210y BindingDB Entry DOI: 10.7270/Q2QV3NCP |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM23316
(7-phenyl-1-{pyrido[2,3-d][1,3]oxazol-2-yl}heptan-1...)Show InChI InChI=1S/C19H20N2O2/c22-16(19-21-18-17(23-19)13-8-14-20-18)12-7-2-1-4-9-15-10-5-3-6-11-15/h3,5-6,8,10-11,13-14H,1-2,4,7,9,12H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of FAAH |
Bioorg Med Chem Lett 21: 4674-85 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.096 BindingDB Entry DOI: 10.7270/Q2W959JK |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50161512
(7-Phenyl-1-(5-(pyridin-2-yl)-1,3,4-oxadiazol-2-yl)...)Show InChI InChI=1S/C20H21N3O2/c24-18(14-7-2-1-4-10-16-11-5-3-6-12-16)20-23-22-19(25-20)17-13-8-9-15-21-17/h3,5-6,8-9,11-13,15H,1-2,4,7,10,14H2 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| 0.290 | n/a | n/a | n/a | n/a | n/a | n/a | 9.0 | n/a |
Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of rat FAAH expressed in Escherichia coli at pH 9.0 |
J Med Chem 51: 4392-403 (2008)
Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50161512
(7-Phenyl-1-(5-(pyridin-2-yl)-1,3,4-oxadiazol-2-yl)...)Show InChI InChI=1S/C20H21N3O2/c24-18(14-7-2-1-4-10-16-11-5-3-6-12-16)20-23-22-19(25-20)17-13-8-9-15-21-17/h3,5-6,8-9,11-13,15H,1-2,4,7,10,14H2 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| 0.290 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of rat FAAH expressed in Escherichia coli |
J Med Chem 51: 4392-403 (2008)
Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50262032
(3-(Biphenyl-4-yl)-1-(5-(pyridin-2-yl)-1,3,4-oxadia...)Show SMILES O=C(CCc1ccc(cc1)-c1ccccc1)c1nnc(o1)-c1ccccn1 Show InChI InChI=1S/C22H17N3O2/c26-20(22-25-24-21(27-22)19-8-4-5-15-23-19)14-11-16-9-12-18(13-10-16)17-6-2-1-3-7-17/h1-10,12-13,15H,11,14H2 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of rat FAAH expressed in Escherichia coli |
J Med Chem 51: 4392-403 (2008)
Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3 |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50275119
(1-(oxazolo[4,5-b]pyridin-2-yl)-5-phenylpentan-1-on...)Show InChI InChI=1S/C17H16N2O2/c20-14(10-5-4-9-13-7-2-1-3-8-13)17-19-16-15(21-17)11-6-12-18-16/h1-3,6-8,11-12H,4-5,9-10H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of FAAH |
Bioorg Med Chem Lett 21: 4674-85 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.096 BindingDB Entry DOI: 10.7270/Q2W959JK |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50262244
(1-(1-Methyl-1H-tetrazol-5-yl)-7-phenylheptan-1-one...)Show InChI InChI=1S/C20H21N3O2/c24-18(14-7-2-1-4-10-16-11-5-3-6-12-16)20-22-19(23-25-20)17-13-8-9-15-21-17/h3,5-6,8-9,11-13,15H,1-2,4,7,10,14H2 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.340 | n/a | n/a | n/a | n/a | n/a | n/a | 9.0 | n/a |
Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of rat FAAH expressed in Escherichia coli at pH 9.0 |
J Med Chem 51: 4392-403 (2008)
Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3 |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50261990
(1-(3-(6-Cyanopiridin-2-yl)-1,2,4-oxadiazol-5-yl)-7...)Show InChI InChI=1S/C21H20N4O2/c22-15-17-12-8-13-18(23-17)20-24-21(27-25-20)19(26)14-7-2-1-4-9-16-10-5-3-6-11-16/h3,5-6,8,10-13H,1-2,4,7,9,14H2 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.380 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of rat FAAH expressed in Escherichia coli |
J Med Chem 51: 4392-403 (2008)
Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3 |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50161520
(1-(oxazolo[4,5-b]pyridin-2-yl)-8-phenyloctan-1-one...)Show InChI InChI=1S/C20H22N2O2/c23-17(20-22-19-18(24-20)14-9-15-21-19)13-8-3-1-2-5-10-16-11-6-4-7-12-16/h4,6-7,9,11-12,14-15H,1-3,5,8,10,13H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.390 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of FAAH |
Bioorg Med Chem Lett 21: 4674-85 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.096 BindingDB Entry DOI: 10.7270/Q2W959JK |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50204512
(2-(7-phenylheptanoyl)oxazole-5-carbonitrile | CHEM...)Show InChI InChI=1S/C17H18N2O2/c18-12-15-13-19-17(21-15)16(20)11-7-2-1-4-8-14-9-5-3-6-10-14/h3,5-6,9-10,13H,1-2,4,7-8,11H2 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant FAAH expressed in Escherichia coli |
J Med Chem 51: 937-47 (2008)
Article DOI: 10.1021/jm701210y BindingDB Entry DOI: 10.7270/Q2QV3NCP |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50372374
(CHEMBL258820)Show InChI InChI=1S/C20H16N2O3/c21-12-18-13-22-20(25-18)19(23)11-10-15-6-8-16(9-7-15)14-24-17-4-2-1-3-5-17/h1-9,13H,10-11,14H2 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant FAAH expressed in Escherichia coli |
J Med Chem 51: 937-47 (2008)
Article DOI: 10.1021/jm701210y BindingDB Entry DOI: 10.7270/Q2QV3NCP |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50342116
((S)-(1,3,4-oxadiazol-2-yl)(6-phenoxy-1,2,3,4-tetra...)Show SMILES O=C([C@H]1CCc2cc(Oc3ccccc3)ccc2C1)c1nnco1 |r| Show InChI InChI=1S/C19H16N2O3/c22-18(19-21-20-12-23-19)15-7-6-14-11-17(9-8-13(14)10-15)24-16-4-2-1-3-5-16/h1-5,8-9,11-12,15H,6-7,10H2/t15-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of full-length human FAAH expressed in COS-7 cells assessed as [14C]-labeled oleamide to oleic acid conversion |
J Med Chem 54: 2805-22 (2011)
Article DOI: 10.1021/jm101597x BindingDB Entry DOI: 10.7270/Q2ZK5H08 |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50372374
(CHEMBL258820)Show InChI InChI=1S/C20H16N2O3/c21-12-18-13-22-20(25-18)19(23)11-10-15-6-8-16(9-7-15)14-24-17-4-2-1-3-5-17/h1-9,13H,10-11,14H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.510 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of human recombinant FAAH expressed COS7 cells |
J Med Chem 51: 937-47 (2008)
Article DOI: 10.1021/jm701210y BindingDB Entry DOI: 10.7270/Q2QV3NCP |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50161525
(1-(oxazolo[4,5-b]pyridin-2-yl)-9-phenylnonan-1-one...)Show InChI InChI=1S/C21H24N2O2/c24-18(21-23-20-19(25-21)15-10-16-22-20)14-9-4-2-1-3-6-11-17-12-7-5-8-13-17/h5,7-8,10,12-13,15-16H,1-4,6,9,11,14H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.520 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of FAAH |
Bioorg Med Chem Lett 21: 4674-85 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.096 BindingDB Entry DOI: 10.7270/Q2W959JK |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50372392
(CHEMBL405880)Show SMILES O=C(CCc1ccc(COc2ccccc2)cc1)c1ncc(o1)-c1cccc(n1)C#N Show InChI InChI=1S/C25H19N3O3/c26-15-20-5-4-8-22(28-20)24-16-27-25(31-24)23(29)14-13-18-9-11-19(12-10-18)17-30-21-6-2-1-3-7-21/h1-12,16H,13-14,17H2 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.560 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant FAAH expressed in Escherichia coli |
J Med Chem 51: 937-47 (2008)
Article DOI: 10.1021/jm701210y BindingDB Entry DOI: 10.7270/Q2QV3NCP |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50161511
(1-(5-(Furan-2-yl)-1,3,4-oxadiazol-2-yl)-heptan-1-o...)Show InChI InChI=1S/C19H20N2O3/c22-16(18-20-21-19(24-18)17-13-8-14-23-17)12-7-2-1-4-9-15-10-5-3-6-11-15/h3,5-6,8,10-11,13-14H,1-2,4,7,9,12H2 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.560 | n/a | n/a | n/a | n/a | n/a | n/a | 9.0 | n/a |
Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of rat FAAH expressed in Escherichia coli at pH 9.0 |
J Med Chem 51: 4392-403 (2008)
Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3 |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50350547
(CHEMBL257307)Show InChI InChI=1S/C18H26N2O2/c1-2-3-4-5-6-7-8-9-10-12-15(21)18-20-17-16(22-18)13-11-14-19-17/h11,13-14H,2-10,12H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| 0.570 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of FAAH |
Bioorg Med Chem Lett 21: 4674-85 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.096 BindingDB Entry DOI: 10.7270/Q2W959JK |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50372380
(CHEMBL271745)Show SMILES COC(=O)c1ccc(cn1)-c1cnc(o1)C(=O)CCc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C25H20N2O4/c1-30-25(29)21-13-12-20(15-26-21)23-16-27-24(31-23)22(28)14-9-17-7-10-19(11-8-17)18-5-3-2-4-6-18/h2-8,10-13,15-16H,9,14H2,1H3 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant FAAH expressed in Escherichia coli |
J Med Chem 51: 937-47 (2008)
Article DOI: 10.1021/jm701210y BindingDB Entry DOI: 10.7270/Q2QV3NCP |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50261988
(1-(3-(6-Bromopyridin-2-yl)-1,2,4-oxadiazol-5-yl)-7...)Show InChI InChI=1S/C20H20BrN3O2/c21-18-14-8-12-16(22-18)19-23-20(26-24-19)17(25)13-7-2-1-4-9-15-10-5-3-6-11-15/h3,5-6,8,10-12,14H,1-2,4,7,9,13H2 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.630 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of rat FAAH expressed in Escherichia coli |
J Med Chem 51: 4392-403 (2008)
Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3 |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50372399
(CHEMBL405604)Show SMILES FC(F)(F)c1cnc(o1)C(=O)CCc1ccc(COc2ccccc2)cc1 Show InChI InChI=1S/C20H16F3NO3/c21-20(22,23)18-12-24-19(27-18)17(25)11-10-14-6-8-15(9-7-14)13-26-16-4-2-1-3-5-16/h1-9,12H,10-11,13H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.670 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of human recombinant FAAH expressed COS7 cells |
J Med Chem 51: 937-47 (2008)
Article DOI: 10.1021/jm701210y BindingDB Entry DOI: 10.7270/Q2QV3NCP |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50350545
(CHEMBL257305)Show InChI InChI=1S/C14H18N2O2/c1-2-3-4-5-6-8-11(17)14-16-13-12(18-14)9-7-10-15-13/h7,9-10H,2-6,8H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.690 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of FAAH |
Bioorg Med Chem Lett 21: 4674-85 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.096 BindingDB Entry DOI: 10.7270/Q2W959JK |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50372355
(CHEMBL272452)Show SMILES FC(F)(F)c1cnc(o1)C(=O)CCc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C19H14F3NO2/c20-19(21,22)17-12-23-18(25-17)16(24)11-8-13-6-9-15(10-7-13)14-4-2-1-3-5-14/h1-7,9-10,12H,8,11H2 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant FAAH expressed in Escherichia coli |
J Med Chem 51: 937-47 (2008)
Article DOI: 10.1021/jm701210y BindingDB Entry DOI: 10.7270/Q2QV3NCP |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM23078
(3-(4-phenylphenyl)-1-[5-(pyridin-2-yl)-1,3-oxazol-...)Show SMILES O=C(CCc1ccc(cc1)-c1ccccc1)c1ncc(o1)-c1ccccn1 Show InChI InChI=1S/C23H18N2O2/c26-21(23-25-16-22(27-23)20-8-4-5-15-24-20)14-11-17-9-12-19(13-10-17)18-6-2-1-3-7-18/h1-10,12-13,15-16H,11,14H2 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.75 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant FAAH expressed in Escherichia coli |
J Med Chem 51: 937-47 (2008)
Article DOI: 10.1021/jm701210y BindingDB Entry DOI: 10.7270/Q2QV3NCP |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50350546
(CHEMBL1812708)Show InChI InChI=1S/C16H22N2O2/c1-2-3-4-5-6-7-8-10-13(19)16-18-15-14(20-16)11-9-12-17-15/h9,11-12H,2-8,10H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.75 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of FAAH |
Bioorg Med Chem Lett 21: 4674-85 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.096 BindingDB Entry DOI: 10.7270/Q2W959JK |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM23078
(3-(4-phenylphenyl)-1-[5-(pyridin-2-yl)-1,3-oxazol-...)Show SMILES O=C(CCc1ccc(cc1)-c1ccccc1)c1ncc(o1)-c1ccccn1 Show InChI InChI=1S/C23H18N2O2/c26-21(23-25-16-22(27-23)20-8-4-5-15-24-20)14-11-17-9-12-19(13-10-17)18-6-2-1-3-7-18/h1-10,12-13,15-16H,11,14H2 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.75 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant FAAH expressed in Escherichia coli |
J Med Chem 51: 937-47 (2008)
Article DOI: 10.1021/jm701210y BindingDB Entry DOI: 10.7270/Q2QV3NCP |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50261940
(1-(5-(6-Bromopyridin-2-yl)-1,3,4-oxadiazol-2-yl)-7...)Show InChI InChI=1S/C20H20BrN3O2/c21-18-14-8-12-16(22-18)19-23-24-20(26-19)17(25)13-7-2-1-4-9-15-10-5-3-6-11-15/h3,5-6,8,10-12,14H,1-2,4,7,9,13H2 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of rat FAAH expressed in Escherichia coli |
J Med Chem 51: 4392-403 (2008)
Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3 |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50372372
(CHEMBL272038)Show InChI InChI=1S/C19H14N2O3/c20-12-17-13-21-19(24-17)18(22)11-8-14-6-9-16(10-7-14)23-15-4-2-1-3-5-15/h1-7,9-10,13H,8,11H2 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant FAAH expressed in Escherichia coli |
J Med Chem 51: 937-47 (2008)
Article DOI: 10.1021/jm701210y BindingDB Entry DOI: 10.7270/Q2QV3NCP |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50372399
(CHEMBL405604)Show SMILES FC(F)(F)c1cnc(o1)C(=O)CCc1ccc(COc2ccccc2)cc1 Show InChI InChI=1S/C20H16F3NO3/c21-20(22,23)18-12-24-19(27-18)17(25)11-10-14-6-8-15(9-7-14)13-26-16-4-2-1-3-5-16/h1-9,12H,10-11,13H2 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant FAAH expressed in Escherichia coli |
J Med Chem 51: 937-47 (2008)
Article DOI: 10.1021/jm701210y BindingDB Entry DOI: 10.7270/Q2QV3NCP |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50262186
(7-Phenyl-1-(5-(thien-2-yl)-1,3,4-oxadiazol-2-yl)-h...)Show InChI InChI=1S/C19H20N2O2S/c22-16(18-20-21-19(23-18)17-13-8-14-24-17)12-7-2-1-4-9-15-10-5-3-6-11-15/h3,5-6,8,10-11,13-14H,1-2,4,7,9,12H2 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | 9.0 | n/a |
Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of rat FAAH expressed in Escherichia coli at pH 9.0 |
J Med Chem 51: 4392-403 (2008)
Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3 |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50262420
(7-Phenyl-1-(5-(pyridin-2-yl)-1,3,4-thiadiazol-2-yl...)Show InChI InChI=1S/C20H21N3OS/c24-18(14-7-2-1-4-10-16-11-5-3-6-12-16)20-23-22-19(25-20)17-13-8-9-15-21-17/h3,5-6,8-9,11-13,15H,1-2,4,7,10,14H2 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | 9.0 | n/a |
Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of rat FAAH expressed in Escherichia coli at pH 9.0 |
J Med Chem 51: 4392-403 (2008)
Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3 |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50372372
(CHEMBL272038)Show InChI InChI=1S/C19H14N2O3/c20-12-17-13-21-19(24-17)18(22)11-8-14-6-9-16(10-7-14)23-15-4-2-1-3-5-15/h1-7,9-10,13H,8,11H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.850 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of human recombinant FAAH expressed COS7 cells |
J Med Chem 51: 937-47 (2008)
Article DOI: 10.1021/jm701210y BindingDB Entry DOI: 10.7270/Q2QV3NCP |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50204490
(CHEMBL220784 | methyl 2-(7-phenylheptanoyl)oxazole...)Show InChI InChI=1S/C18H21NO4/c1-22-18(21)16-13-19-17(23-16)15(20)12-8-3-2-5-9-14-10-6-4-7-11-14/h4,6-7,10-11,13H,2-3,5,8-9,12H2,1H3 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.900 | n/a | n/a | n/a | n/a | n/a | n/a | 9.0 | n/a |
Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of rat FAAH expressed in Escherichia coli at pH 9.0 |
J Med Chem 51: 4392-403 (2008)
Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3 |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50262244
(1-(1-Methyl-1H-tetrazol-5-yl)-7-phenylheptan-1-one...)Show InChI InChI=1S/C20H21N3O2/c24-18(14-7-2-1-4-10-16-11-5-3-6-12-16)20-22-19(23-25-20)17-13-8-9-15-21-17/h3,5-6,8-9,11-13,15H,1-2,4,7,10,14H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.920 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of human recombinant FAAH expressed in african green monkey COS7 cells |
J Med Chem 51: 4392-403 (2008)
Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3 |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50342118
((S)-(6-phenoxy-1,2,3,4-tetrahydronaphthalen-2-yl)(...)Show SMILES O=C([C@H]1CCc2cc(Oc3ccccc3)ccc2C1)c1nnc(o1)-c1ccccn1 |r| Show InChI InChI=1S/C24H19N3O3/c28-22(24-27-26-23(30-24)21-8-4-5-13-25-21)18-10-9-17-15-20(12-11-16(17)14-18)29-19-6-2-1-3-7-19/h1-8,11-13,15,18H,9-10,14H2/t18-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of full-length human FAAH expressed in COS-7 cells assessed as [14C]-labeled oleamide to oleic acid conversion |
J Med Chem 54: 2805-22 (2011)
Article DOI: 10.1021/jm101597x BindingDB Entry DOI: 10.7270/Q2ZK5H08 |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50261938
(CHEMBL450158 | Methyl 5-(7-Phenylheptanoyl)-1,3,4-...)Show InChI InChI=1S/C17H20N2O3S/c1-22-17(21)16-19-18-15(23-16)14(20)12-8-3-2-5-9-13-10-6-4-7-11-13/h4,6-7,10-11H,2-3,5,8-9,12H2,1H3 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 1 | n/a | n/a | n/a | n/a | n/a | n/a | 9.0 | n/a |
Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of rat FAAH expressed in Escherichia coli at pH 9.0 |
J Med Chem 51: 4392-403 (2008)
Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3 |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50261936
(CHEMBL468188 | Methyl 5-(7-Phenylheptanoyl)-1,3,4-...)Show InChI InChI=1S/C17H20N2O4/c1-22-17(21)16-19-18-15(23-16)14(20)12-8-3-2-5-9-13-10-6-4-7-11-13/h4,6-7,10-11H,2-3,5,8-9,12H2,1H3 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 1 | n/a | n/a | n/a | n/a | n/a | n/a | 9.0 | n/a |
Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of rat FAAH expressed in Escherichia coli at pH 9.0 |
J Med Chem 51: 4392-403 (2008)
Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3 |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50261938
(CHEMBL450158 | Methyl 5-(7-Phenylheptanoyl)-1,3,4-...)Show InChI InChI=1S/C17H20N2O3S/c1-22-17(21)16-19-18-15(23-16)14(20)12-8-3-2-5-9-13-10-6-4-7-11-13/h4,6-7,10-11H,2-3,5,8-9,12H2,1H3 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of rat FAAH expressed in Escherichia coli |
J Med Chem 51: 4392-403 (2008)
Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3 |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50261941
(1-(3-(6-Chloropyridin-2-yl)-1,2,4-oxadiazol-5-yl)-...)Show InChI InChI=1S/C20H20ClN3O2/c21-18-14-8-12-16(22-18)19-23-20(26-24-19)17(25)13-7-2-1-4-9-15-10-5-3-6-11-15/h3,5-6,8,10-12,14H,1-2,4,7,9,13H2 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of rat FAAH expressed in Escherichia coli |
J Med Chem 51: 4392-403 (2008)
Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3 |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50261989
(1-(3-(6-Iodopyridin-2-yl)-1,2,4-oxadiazol-5-yl)-7-...)Show InChI InChI=1S/C20H20IN3O2/c21-18-14-8-12-16(22-18)19-23-20(26-24-19)17(25)13-7-2-1-4-9-15-10-5-3-6-11-15/h3,5-6,8,10-12,14H,1-2,4,7,9,13H2 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of rat FAAH expressed in Escherichia coli |
J Med Chem 51: 4392-403 (2008)
Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3 |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM23073
(3-[4-(phenoxymethyl)phenyl]-1-[5-(pyridin-2-yl)-1,...)Show SMILES O=C(CCc1ccc(COc2ccccc2)cc1)c1ncc(o1)-c1ccccn1 Show InChI InChI=1S/C24H20N2O3/c27-22(24-26-16-23(29-24)21-8-4-5-15-25-21)14-13-18-9-11-19(12-10-18)17-28-20-6-2-1-3-7-20/h1-12,15-16H,13-14,17H2 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant FAAH expressed in Escherichia coli |
J Med Chem 51: 937-47 (2008)
Article DOI: 10.1021/jm701210y BindingDB Entry DOI: 10.7270/Q2QV3NCP |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50372364
(CHEMBL271792)Show SMILES FC(F)(F)c1cnc(o1)C(=O)CCc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C19H14F3NO3/c20-19(21,22)17-12-23-18(26-17)16(24)11-8-13-6-9-15(10-7-13)25-14-4-2-1-3-5-14/h1-7,9-10,12H,8,11H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of human recombinant FAAH expressed COS7 cells |
J Med Chem 51: 937-47 (2008)
Article DOI: 10.1021/jm701210y BindingDB Entry DOI: 10.7270/Q2QV3NCP |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM23073
(3-[4-(phenoxymethyl)phenyl]-1-[5-(pyridin-2-yl)-1,...)Show SMILES O=C(CCc1ccc(COc2ccccc2)cc1)c1ncc(o1)-c1ccccn1 Show InChI InChI=1S/C24H20N2O3/c27-22(24-26-16-23(29-24)21-8-4-5-15-25-21)14-13-18-9-11-19(12-10-18)17-28-20-6-2-1-3-7-20/h1-12,15-16H,13-14,17H2 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant FAAH expressed in Escherichia coli |
J Med Chem 51: 937-47 (2008)
Article DOI: 10.1021/jm701210y BindingDB Entry DOI: 10.7270/Q2QV3NCP |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50262135
(1-(1,3,4-Oxadiazol-2-yl)-7-phenylheptan-1-one | CH...)Show InChI InChI=1S/C15H18N2O2/c18-14(15-17-16-12-19-15)11-7-2-1-4-8-13-9-5-3-6-10-13/h3,5-6,9-10,12H,1-2,4,7-8,11H2 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 1 | n/a | n/a | n/a | n/a | n/a | n/a | 9.0 | n/a |
Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of rat FAAH expressed in Escherichia coli at pH 9.0 |
J Med Chem 51: 4392-403 (2008)
Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3 |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50262188
(1-(1,2,4-Oxadiazol-5-yl)-7-phenylheptan-1-one | CH...)Show InChI InChI=1S/C15H18N2O2/c18-14(15-16-12-17-19-15)11-7-2-1-4-8-13-9-5-3-6-10-13/h3,5-6,9-10,12H,1-2,4,7-8,11H2 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 1 | n/a | n/a | n/a | n/a | n/a | n/a | 9.0 | n/a |
Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of rat FAAH expressed in Escherichia coli at pH 9.0 |
J Med Chem 51: 4392-403 (2008)
Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3 |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50262245
(1-(3-(Furan-2-yl)-1,2,4-oxadiazol-5-yl)-7-phenylhe...)Show InChI InChI=1S/C19H20N2O3/c22-16(19-20-18(21-24-19)17-13-8-14-23-17)12-7-2-1-4-9-15-10-5-3-6-11-15/h3,5-6,8,10-11,13-14H,1-2,4,7,9,12H2 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 1 | n/a | n/a | n/a | n/a | n/a | n/a | 9.0 | n/a |
Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of rat FAAH expressed in Escherichia coli at pH 9.0 |
J Med Chem 51: 4392-403 (2008)
Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3 |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50262306
(7-Phenyl-1-(5-(pyridin-2-yl)-1,2,4-oxadiazol-3-yl)...)Show InChI InChI=1S/C20H21N3O2/c24-18(14-7-2-1-4-10-16-11-5-3-6-12-16)19-22-20(25-23-19)17-13-8-9-15-21-17/h3,5-6,8-9,11-13,15H,1-2,4,7,10,14H2 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of rat FAAH expressed in Escherichia coli |
J Med Chem 51: 4392-403 (2008)
Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3 |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50262306
(7-Phenyl-1-(5-(pyridin-2-yl)-1,2,4-oxadiazol-3-yl)...)Show InChI InChI=1S/C20H21N3O2/c24-18(14-7-2-1-4-10-16-11-5-3-6-12-16)19-22-20(25-23-19)17-13-8-9-15-21-17/h3,5-6,8-9,11-13,15H,1-2,4,7,10,14H2 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | 9.0 | n/a |
Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of rat FAAH expressed in Escherichia coli at pH 9.0 |
J Med Chem 51: 4392-403 (2008)
Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3 |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 [30-579]
(Rattus norvegicus (rat)) | BDBM50372381
(CHEMBL270929)Show SMILES O=C(CCc1ccc(cc1)-c1ccccc1)c1ncc(o1)-c1cccnc1 Show InChI InChI=1S/C23H18N2O2/c26-21(23-25-16-22(27-23)20-7-4-14-24-15-20)13-10-17-8-11-19(12-9-17)18-5-2-1-3-6-18/h1-9,11-12,14-16H,10,13H2 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant FAAH expressed in Escherichia coli |
J Med Chem 51: 937-47 (2008)
Article DOI: 10.1021/jm701210y BindingDB Entry DOI: 10.7270/Q2QV3NCP |
More data for this Ligand-Target Pair | |