| Reaction Details |
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 | Report a problem with these data |
| Target | Isocitrate lyase |
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| Ligand | BDBM50206257 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_537411 (CHEMBL992601) |
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| IC50 | 157500±n/a nM |
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| Citation |  Lee, D; Shin, J; Yoon, KM; Kim, TI; Lee, SH; Lee, HS; Oh, KB Inhibition of Candida albicans isocitrate lyase activity by sesterterpene sulfates from the tropical sponge Dysidea sp. Bioorg Med Chem Lett18:5377-80 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Isocitrate lyase |
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| Name: | Isocitrate lyase |
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| Synonyms: | ACEA_CANAX | ICL1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 61398.95 |
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| Organism: | Candida albicans |
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| Description: | ChEMBL_972063 |
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| Residue: | 550 |
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| Sequence: | MPYTPIDIQKEEADFQKEVAEIKKWWSEPRWRKTKRIYSAEDIAKKRGTLKINHPSSQQA
DKLFKLLETHDADKTVSFTFGALDPIHVAQMAKYLDSIYVSGWQCSSTASTSNEPSPDLA
DYPMDTVPNKVEHLWFAQLFHDRKQREERLTLSKEERAKTPYIDFLRPIIADADTGHGGI
TAIIKLTKMFIERGAAGIHIEDQAPGTKKCGHMAGKVLVPVQEHINRLVAIRASADIFGS
NLLAVARTDSEAATLITSTIDHRDHYFIIGATNPEAGDLAALMAEAESKGIYGNELAAIE
SEWTKKAGLKLFHEAVIDEIKNGNYSNKDALIKKFTDKVNPLSHTSHKEAKKLAKELTGK
DIYFNWDVARAREGYYRYQGGTQCAVMRGRAFAPYADLIWMESALPDYAQAKEFADGVKA
AVPDQWLAYNLSPSFNWNKAMPADEQETYIKRLGKLGYVWQFITLAGLHTTALAVDDFSN
QYSQIGMKAYGQTVQQPEIEKGVEVVKHQKWSGATYIDGLLKMVSGGVTSTAAMGQGVTE
DQFKESKAKA
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| BDBM50206257 |
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| n/a |
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| Name | BDBM50206257 |
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| Synonyms: | CHEMBL387584 | CHEMBL450482 | halisulfate 1 | sodium (2R,3R)-9-(2,5-dihydroxyphenyl)-3,7-dimethyl-1-((1S,4aS,8aS)-2,5,5,8a-tetramethyl-1,4,4a,5,6,7,8,8a-octahydronaphthalen-1-yl)non-7-en-2-yl sulfate |
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| Type | Small organic molecule |
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| Emp. Form. | C31H47O6S |
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| Mol. Mass. | 547.767 |
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| SMILES | C[C@H](CCC\C(C)=C\Cc1cc(O)ccc1O)[C@@H](C[C@H]1C(C)=CC[C@H]2C(C)(C)CCC[C@]12C)OS([O-])(=O)=O |r,c:22| |
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| Structure | 
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