| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Isocitrate lyase |
|---|
| Ligand | BDBM50274514 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_537411 (CHEMBL992601) |
|---|
| IC50 | 31300±n/a nM |
|---|
| Citation |  Lee, D; Shin, J; Yoon, KM; Kim, TI; Lee, SH; Lee, HS; Oh, KB Inhibition of Candida albicans isocitrate lyase activity by sesterterpene sulfates from the tropical sponge Dysidea sp. Bioorg Med Chem Lett18:5377-80 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Isocitrate lyase |
|---|
| Name: | Isocitrate lyase |
|---|
| Synonyms: | ACEA_CANAX | ICL1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 61398.95 |
|---|
| Organism: | Candida albicans |
|---|
| Description: | ChEMBL_972063 |
|---|
| Residue: | 550 |
|---|
| Sequence: | MPYTPIDIQKEEADFQKEVAEIKKWWSEPRWRKTKRIYSAEDIAKKRGTLKINHPSSQQA
DKLFKLLETHDADKTVSFTFGALDPIHVAQMAKYLDSIYVSGWQCSSTASTSNEPSPDLA
DYPMDTVPNKVEHLWFAQLFHDRKQREERLTLSKEERAKTPYIDFLRPIIADADTGHGGI
TAIIKLTKMFIERGAAGIHIEDQAPGTKKCGHMAGKVLVPVQEHINRLVAIRASADIFGS
NLLAVARTDSEAATLITSTIDHRDHYFIIGATNPEAGDLAALMAEAESKGIYGNELAAIE
SEWTKKAGLKLFHEAVIDEIKNGNYSNKDALIKKFTDKVNPLSHTSHKEAKKLAKELTGK
DIYFNWDVARAREGYYRYQGGTQCAVMRGRAFAPYADLIWMESALPDYAQAKEFADGVKA
AVPDQWLAYNLSPSFNWNKAMPADEQETYIKRLGKLGYVWQFITLAGLHTTALAVDDFSN
QYSQIGMKAYGQTVQQPEIEKGVEVVKHQKWSGATYIDGLLKMVSGGVTSTAAMGQGVTE
DQFKESKAKA
|
|
|
|---|
| BDBM50274514 |
|---|
| n/a |
|---|
| Name | BDBM50274514 |
|---|
| Synonyms: | CHEMBL492072 | [amino(dimethylamino)methylidene]azanium (2S)-2-{2-[(1S,2R,4aS,8aR)-1,2,4a-trimethyl-5-methylidene-decahydronaphthalen-1-yl]ethyl}-5-(furan-3-yl)pentyl sulfate |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H39O5S |
|---|
| Mol. Mass. | 451.64 |
|---|
| SMILES | C[C@@H]1CC[C@@]2(C)[C@H](CCCC2=C)[C@@]1(C)CC[C@H](CCCc1ccoc1)COS([O-])(=O)=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
