| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 4-hydroxy-tetrahydrodipicolinate synthase |
|---|
| Ligand | BDBM50273975 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_536820 (CHEMBL988084) |
|---|
| Ki | 830000±n/a nM |
|---|
| Citation |  Boughton, BA; Griffin, MD; O'Donnell, PA; Dobson, RC; Perugini, MA; Gerrard, JA; Hutton, CA Irreversible inhibition of dihydrodipicolinate synthase by 4-oxo-heptenedioic acid analogues. Bioorg Med Chem16:9975-83 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 4-hydroxy-tetrahydrodipicolinate synthase |
|---|
| Name: | 4-hydroxy-tetrahydrodipicolinate synthase |
|---|
| Synonyms: | DAPA_ECOLI | Dihydrodipicolinate synthase | dapA |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 31269.12 |
|---|
| Organism: | Escherichia coli (strain K12) |
|---|
| Description: | ChEMBL_536816 |
|---|
| Residue: | 292 |
|---|
| Sequence: | MFTGSIVAIVTPMDEKGNVCRASLKKLIDYHVASGTSAIVSVGTTGESATLNHDEHADVV
MMTLDLADGRIPVIAGTGANATAEAISLTQRFNDSGIVGCLTVTPYYNRPSQEGLYQHFK
AIAEHTDLPQILYNVPSRTGCDLLPETVGRLAKVKNIIGIKEATGNLTRVNQIKELVSDD
FVLLSGDDASALDFMQLGGHGVISVTANVAARDMAQMCKLAAEGHFAEARVINQRLMPLH
NKLFVEPNPIPVKWACKELGLVATDTLRLPMTPITDSGRETVRAALKHAGLL
|
|
|
|---|
| BDBM50273975 |
|---|
| n/a |
|---|
| Name | BDBM50273975 |
|---|
| Synonyms: | 2-ketobutyrate | 2-oxobutanate | 2-oxobutanoate | alpha-ketobutyrate | alpha-oxobutyrate |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C4H5O3 |
|---|
| Mol. Mass. | 101.0812 |
|---|
| SMILES | CCC(=O)C([O-])=O |
|---|
| Structure | 
|
|---|
Search and Browse
