| Reaction Details |
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 | Report a problem with these data |
| Target | Galanin receptor type 2 |
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| Ligand | BDBM50273351 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_561975 (CHEMBL1010038) |
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| Ki | 13±n/a nM |
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| Citation |  Bulaj, G; Green, BR; Lee, HK; Robertson, CR; White, K; Zhang, L; Sochanska, M; Flynn, SP; Scholl, EA; Pruess, TH; Smith, MD; White, HS Design, synthesis, and characterization of high-affinity, systemically-active galanin analogues with potent anticonvulsant activities. J Med Chem51:8038-47 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Galanin receptor type 2 |
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| Name: | Galanin receptor type 2 |
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| Synonyms: | GALNR2 | GALR2 | GALR2_HUMAN | Galanin R2 | Galanin receptor 2 | Galanin receptor type 2 | Galanin receptor type 2 (GAL2-R) (GALR2). |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 41724.40 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Galanin R2 GALR2 HUMAN::O43603 |
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| Residue: | 387 |
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| Sequence: | MNVSGCPGAGNASQAGGGGGWHPEAVIVPLLFALIFLVGTVGNTLVLAVLLRGGQAVSTT
NLFILNLGVADLCFILCCVPFQATIYTLDGWVFGSLLCKAVHFLIFLTMHASSFTLAAVS
LDRYLAIRYPLHSRELRTPRNALAAIGLIWGLSLLFSGPYLSYYRQSQLANLTVCHPAWS
APRRRAMDICTFVFSYLLPVLVLGLTYARTLRYLWRAVDPVAAGSGARRAKRKVTRMILI
VAALFCLCWMPHHALILCVWFGQFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFR
KGFRTICAGLLGRAPGRASGRVCAAARGTHSGSVLERESSDLLHMSEAAGALRPCPGASQ
PCILEPCPGPSWQGPKAGDSILTVDVA
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| BDBM50273351 |
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| n/a |
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| Name | BDBM50273351 |
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| Synonyms: | CHEMBL508083 | GWTLNSAGYLLGPHAV-NH2 |
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| Type | Small organic molecule |
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| Emp. Form. | C77H115N21O20 |
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| Mol. Mass. | 1654.8657 |
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| SMILES | CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@H](C)O)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(N)=O |r| |
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| Structure | 
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