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TargetGalanin receptor 2
LigandBDBM50273351
Substrate/Competitorn/a
Meas. Tech.ChEMBL_561975
Ki 13±n/a nM
Citation Bulaj GGreen BRLee HKRobertson CRWhite KZhang LSochanska MFlynn SPScholl EAPruess THSmith MDWhite HS Design, synthesis, and characterization of high-affinity, systemically-active galanin analogues with potent anticonvulsant activities. J Med Chem 51:8038-47 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Galanin receptor 2
Name:Galanin receptor 2
Synonyms:GALR2 | Galanin R2 | Galanin receptor 2 | Galanin receptor type 2 | Galanin receptor type 2 (GAL2-R) (GALR2).
Type:Enzyme Catalytic Domain
Mol. Mass.:41724.40
Organism:Homo sapiens (Human)
Description:Galanin R2 GALR2 HUMAN::O43603
Residue:387
Sequence:
MNVSGCPGAGNASQAGGGGGWHPEAVIVPLLFALIFLVGTVGNTLVLAVLLRGGQAVSTT
NLFILNLGVADLCFILCCVPFQATIYTLDGWVFGSLLCKAVHFLIFLTMHASSFTLAAVS
LDRYLAIRYPLHSRELRTPRNALAAIGLIWGLSLLFSGPYLSYYRQSQLANLTVCHPAWS
APRRRAMDICTFVFSYLLPVLVLGLTYARTLRYLWRAVDPVAAGSGARRAKRKVTRMILI
VAALFCLCWMPHHALILCVWFGQFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFR
KGFRTICAGLLGRAPGRASGRVCAAARGTHSGSVLERESSDLLHMSEAAGALRPCPGASQ
PCILEPCPGPSWQGPKAGDSILTVDVA
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  Blast E-value cutoff:
BDBM50273351
n/a
NameBDBM50273351
Synonyms:CHEMBL508083 | GWTLNSAGYLLGPHAV-NH2
TypeSmall organic molecule
Emp. Form.C77H115N21O20
Mol. Mass.1654.8657
SMILESCC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@H](C)O)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(N)=O |r|
Structure
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