| Reaction Details |
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 | Report a problem with these data |
| Target | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal |
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| Ligand | BDBM50174558 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_543345 (CHEMBL1023015) |
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| IC50 | 616580±n/a nM |
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| Citation |  Freitas, RF; Prokopczyk, IM; Zottis, A; Oliva, G; Andricopulo, AD; Trevisan, MT; Vilegas, W; Silva, MG; Montanari, CA Discovery of novel Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase inhibitors. Bioorg Med Chem17:2476-82 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glyceraldehyde-3-phosphate dehydrogenase, glycosomal |
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| Name: | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal |
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| Synonyms: | G3PG_TRYCR |
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| Type: | PROTEIN |
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| Mol. Mass.: | 39070.68 |
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| Organism: | Trypanosoma cruzi |
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| Description: | ChEMBL_973242 |
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| Residue: | 359 |
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| Sequence: | MPIKVGINGFGRIGRMVFQALCEDGLLGTEIDVVAVVDMNTDAEYFAYQMRYDTVHGKFK
YEVTTTKSSPSVAKDDTLVVNGHRILCVKAQRNPADLPWGKLGVEYVIESTGLFTAKAAA
EGHLRGGARKVVISAPASGGAKTLVMGVNHHEYNPSEHHVVSNASCTTNCLAPIVHVLVK
EGFGVQTGLMTTIHSYTATQKTVDGVSVKDWRGGRAAAVNIIPSTTGAAKAVGMVIPSTQ
GKLTGMSFRVPTPDVSVVDLTFTAARDTSIQEIDAALKRASKTYMKGILGYTDEELVSAD
FINDNRSSIYDSKATLQNNLPKERRFFKIVSWYDNEWGYSHRVVDLVRHMASKDRSARL
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| BDBM50174558 |
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| n/a |
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| Name | BDBM50174558 |
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| Synonyms: | 7-hydroxy-2H-1-benzopyran-2-one | 7-hydroxy-2H-chromen-2-one | CHEMBL51628 | Coumarin derivative, 3a | beta-umbelliferone | hydrangin | skimmetin | umbelliferone |
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| Type | Small organic molecule |
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| Emp. Form. | C9H6O3 |
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| Mol. Mass. | 162.1421 |
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| SMILES | Oc1ccc2ccc(=O)oc2c1 |
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| Structure | 
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