| Reaction Details |
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 | Report a problem with these data |
| Target | D(1A) dopamine receptor |
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| Ligand | BDBM50378014 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_563537 (CHEMBL961824) |
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| Ki | >10000±n/a nM |
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| Citation |  Newman, AH; Grundt, P; Cyriac, G; Deschamps, JR; Taylor, M; Kumar, R; Ho, D; Luedtke, RR N-(4-(4-(2,3-dichloro- or 2-methoxyphenyl)piperazin-1-yl)butyl)heterobiarylcarboxamides with functionalized linking chains as high affinity and enantioselective D3 receptor antagonists. J Med Chem52:2559-70 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(1A) dopamine receptor |
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| Name: | D(1A) dopamine receptor |
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| Synonyms: | DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A |
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| Type: | Enzyme |
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| Mol. Mass.: | 49303.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21728 |
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| Residue: | 446 |
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| Sequence: | MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTN
FFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVD
RYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLA
ETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKN
CQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGS
GETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIET
VSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPAL
SVILDYDTDVSLEKIQPITQNGQHPT
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| BDBM50378014 |
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| n/a |
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| Name | BDBM50378014 |
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| Synonyms: | CHEMBL1627308 | US8748608, 35 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H30N4O3 |
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| Mol. Mass. | 422.52 |
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| SMILES | COc1ccccc1N1CCN(CC(O)CCNC(=O)c2cc3ccccc3[nH]2)CC1 |
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| Structure | 
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