Reaction Details | |||
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Target | Melanocyte-stimulating hormone receptor | ||
Ligand | BDBM50301154 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_598563 (CHEMBL1043555) | ||
EC50 | 3030±n/a nM | ||
Citation | Ruwe, AR; Koikov, L; Abdel-Malek, Z; Haskell-Luevano, C; Dirain, ML; Portillo, F; Xiang, Z; Wortman, M; Knittel, JJ Semi-rigid tripeptide agonists of melanocortin receptors. Bioorg Med Chem Lett19:5176-81 (2009) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Melanocyte-stimulating hormone receptor | |||
Name: | Melanocyte-stimulating hormone receptor | ||
Synonyms: | MC1-R | MSHR_MOUSE | Mc1r | Melanocortin receptor 1 | Melanocyte-stimulating hormone receptor | Msh-r | ||
Type: | PROTEIN | ||
Mol. Mass.: | 35238.60 | ||
Organism: | Mus musculus | ||
Description: | ChEMBL_1498846 | ||
Residue: | 315 | ||
Sequence: |
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BDBM50301154 | |||
n/a | |||
Name | BDBM50301154 | ||
Synonyms: | CHEMBL569086 | N-((S)-1-((R)-1-((S)-1-amino-5-guanidino-1-oxopentan-2-ylamino)-1-oxo-3-phenylpropan-2-ylamino)-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl)benzo[d][1,3]dioxole-5-carboxamide | ||
Type | Small organic molecule | ||
Emp. Form. | C29H35N9O6 | ||
Mol. Mass. | 605.6449 | ||
SMILES | NC(N)=NCCC[C@@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)c1ccc2OCOc2c1)C(N)=O |r,wU:22.30,7.7,wD:11.19,(33.59,-9.4,;32.25,-8.63,;32.26,-7.09,;30.92,-9.4,;29.57,-8.64,;28.25,-9.41,;26.92,-8.64,;26.92,-7.1,;25.58,-6.33,;24.25,-7.1,;24.25,-8.64,;22.92,-6.33,;22.92,-4.79,;21.58,-4.02,;21.58,-2.48,;20.25,-1.71,;18.92,-2.48,;18.92,-4.02,;20.25,-4.79,;21.59,-7.1,;21.6,-8.64,;22.93,-9.4,;20.27,-9.4,;18.93,-8.64,;17.6,-9.4,;16.2,-8.78,;15.16,-9.93,;15.93,-11.25,;17.44,-10.93,;20.25,-10.94,;21.59,-11.71,;22.93,-10.93,;21.59,-13.25,;22.92,-14.01,;22.92,-15.54,;21.59,-16.32,;21.27,-17.83,;19.74,-18,;19.11,-16.59,;20.25,-15.56,;20.24,-14.01,;28.25,-6.33,;29.58,-7.1,;28.25,-4.79,)| | ||
Structure |