Reaction Details | |||
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Target | Melanocortin receptor 5 | ||
Ligand | BDBM50301130 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_598566 (CHEMBL1043558) | ||
EC50 | 6780±n/a nM | ||
Citation | Ruwe, AR; Koikov, L; Abdel-Malek, Z; Haskell-Luevano, C; Dirain, ML; Portillo, F; Xiang, Z; Wortman, M; Knittel, JJ Semi-rigid tripeptide agonists of melanocortin receptors. Bioorg Med Chem Lett19:5176-81 (2009) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Melanocortin receptor 5 | |||
Name: | Melanocortin receptor 5 | ||
Synonyms: | MC5R_MOUSE | Mc5r | Melanocortin receptor 5 | Melanocortin receptor 5 (MC5R) | ||
Type: | Enzyme | ||
Mol. Mass.: | 36966.58 | ||
Organism: | Mus musculus (Mouse) | ||
Description: | P41149 | ||
Residue: | 325 | ||
Sequence: |
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BDBM50301130 | |||
n/a | |||
Name | BDBM50301130 | ||
Synonyms: | (S)-2-((R)-2-((S)-3-(1H-imidazol-5-yl)-2-(3-(3-(trifluoromethyl)phenyl)acrylamido)propanamido)-3-phenylpropanamido)-5-guanidinopentanamide | CHEMBL569696 | ||
Type | Small organic molecule | ||
Emp. Form. | C31H36F3N9O4 | ||
Mol. Mass. | 655.6706 | ||
SMILES | NC(N)=NCCC[C@@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)C=Cc1cccc(c1)C(F)(F)F)C(N)=O |r,w:32.33,wU:22.30,7.7,wD:11.19,(9.88,-27.18,;8.54,-26.42,;8.55,-24.87,;7.21,-27.19,;5.87,-26.42,;4.54,-27.19,;3.21,-26.42,;3.21,-24.88,;1.87,-24.11,;.54,-24.88,;.54,-26.42,;-.79,-24.11,;-.79,-22.57,;-2.13,-21.8,;-2.13,-20.26,;-3.46,-19.49,;-4.79,-20.26,;-4.79,-21.8,;-3.46,-22.57,;-2.13,-24.88,;-2.12,-26.42,;-.78,-27.19,;-3.45,-27.19,;-4.78,-26.42,;-6.12,-27.19,;-7.52,-26.56,;-8.55,-27.71,;-7.78,-29.04,;-6.28,-28.72,;-3.46,-28.73,;-2.12,-29.49,;-.79,-28.72,;-2.12,-31.03,;-3.46,-31.8,;-3.46,-33.34,;-4.8,-34.1,;-4.8,-35.64,;-3.46,-36.41,;-2.12,-35.63,;-2.13,-34.1,;-.79,-36.4,;-.78,-37.94,;.54,-35.62,;.54,-37.17,;4.54,-24.11,;5.87,-24.88,;4.54,-22.57,)| | ||
Structure |