| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin D2 receptor |
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| Ligand | BDBM50302819 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_595294 (CHEMBL1047088) |
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| IC50 | 132±n/a nM |
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| Citation |  Liu, J; Fu, Z; Wang, Y; Schmitt, M; Huang, A; Marshall, D; Tonn, G; Seitz, L; Sullivan, T; Lucy Tang, H; Collins, T; Medina, J Discovery and optimization of CRTH2 and DP dual antagonists. Bioorg Med Chem Lett19:6419-23 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin D2 receptor |
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| Name: | Prostaglandin D2 receptor |
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| Synonyms: | PD2R_HUMAN | PTGDR | Prostaglandin D2 | Prostaglandin D2 receptor | Prostanoid DP receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 40288.87 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q13258 |
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| Residue: | 359 |
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| Sequence: | MKSPFYRCQNTTSVEKGNSAVMGGVLFSTGLLGNLLALGLLARSGLGWCSRRPLRPLPSV
FYMLVCGLTVTDLLGKCLLSPVVLAAYAQNRSLRVLAPALDNSLCQAFAFFMSFFGLSST
LQLLAMALECWLSLGHPFFYRRHITLRLGALVAPVVSAFSLAFCALPFMGFGKFVQYCPG
TWCFIQMVHEEGSLSVLGYSVLYSSLMALLVLATVLCNLGAMRNLYAMHRRLQRHPRSCT
RDCAEPRADGREASPQPLEELDHLLLLALMTVLFTMCSLPVIYRAYYGAFKDVKEKNRTS
EEAEDLRALRFLSVISIVDPWIFIIFRSPVFRIFFHKIFIRPLRYRSRCSNSTNMESSL
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| BDBM50302819 |
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| n/a |
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| Name | BDBM50302819 |
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| Synonyms: | 4-(4-((1H-tetrazol-5-yl)methyl)phenoxy)-3-(2,4-dichlorophenylsulfonamido)-N-ethylbenzamide | CHEMBL570669 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H20Cl2N6O4S |
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| Mol. Mass. | 547.414 |
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| SMILES | CCNC(=O)c1ccc(Oc2ccc(Cc3nnn[nH]3)cc2)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 |
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| Structure | 
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