| Reaction Details |
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 | Report a problem with these data |
| Target | P2Y purinoceptor 6 |
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| Ligand | BDBM50199173 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_611873 (CHEMBL1070828) |
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| EC50 | 130±n/a nM |
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| Citation |  Ginsburg-Shmuel, T; Haas, M; Schumann, M; Reiser, G; Kalid, O; Stern, N; Fischer, B 5-OMe-UDP is a potent and selective P2Y(6)-receptor agonist. J Med Chem53:1673-85 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| P2Y purinoceptor 6 |
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| Name: | P2Y purinoceptor 6 |
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| Synonyms: | P2RY6_RAT | P2ry6 | Pyrimidinergic receptor P2Y6 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36704.21 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_805344 |
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| Residue: | 328 |
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| Sequence: | MERDNGTIQAPGLPPTTCVYREDFKRLLLPPVYSVVLVVGLPLNVCVIAQICASRRTLTR
SAVYTLNLALADLLYACSLPLLIYNYARGDHWPFGDLACRLVRFLFYANLHGSILFLTCI
SFQRYLGICHPLAPWHKRGGRRAAWVVCGVVWLVVTAQCLPTAVFAATGIQRNRTVCYDL
SPPILSTRYLPYGMALTVIGFLLPFTALLACYCRMARRLCRQDGPAGPVAQERRSKAARM
AVVVAAVFVISFLPFHITKTAYLAVRSTPGVSCPVLETFAAAYKGTRPFASANSVLDPIL
FYFTQQKFRRQPHDLLQKLTAKWQRQRV
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| BDBM50199173 |
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| n/a |
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| Name | BDBM50199173 |
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| Synonyms: | ((2R,3S,4R,5R)-5-(5-bromo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl trihydrogen diphosphate | 5-bromo-1-beta-D-ribofuranosyl(3H)pyrimidine-2,4-dione 5'-diphosphate | CHEMBL214698 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H13BrN2O12P2 |
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| Mol. Mass. | 483.057 |
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| SMILES | O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(O)=O)n1cc(Br)c(=O)[nH]c1=O |
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| Structure | 
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