| Reaction Details |
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 | Report a problem with these data |
| Target | D(1A) dopamine receptor |
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| Ligand | BDBM50234265 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_611184 (CHEMBL1065706) |
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| Ki | 46±n/a nM |
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| Citation |  Liu, Z; Zhang, H; Ye, N; Zhang, J; Wu, Q; Sun, P; Li, L; Zhen, X; Zhang, A Synthesis of dihydrofuroaporphine derivatives: identification of a potent and selective serotonin 5-HT 1A receptor agonist. J Med Chem53:1319-28 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(1A) dopamine receptor |
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| Name: | D(1A) dopamine receptor |
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| Synonyms: | DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A |
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| Type: | Enzyme |
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| Mol. Mass.: | 49303.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21728 |
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| Residue: | 446 |
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| Sequence: | MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTN
FFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVD
RYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLA
ETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKN
CQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGS
GETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIET
VSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPAL
SVILDYDTDVSLEKIQPITQNGQHPT
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| BDBM50234265 |
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| n/a |
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| Name | BDBM50234265 |
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| Synonyms: | (R)-(-)-2-methoxy-11-hydroxyaporphine | 2-Methoxy-11-hydroxyaporphine | CHEMBL270426 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H19NO2 |
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| Mol. Mass. | 281.349 |
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| SMILES | COc1cc2CCN(C)[C@@H]3Cc4cccc(O)c4-c(c1)c23 |r| |
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| Structure | 
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