| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 13 |
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| Ligand | BDBM50167367 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_635039 (CHEMBL1118590) |
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| Ki | 994±n/a nM |
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| Citation |  Di Fiore, A; Monti, SM; Innocenti, A; Winum, JY; De Simone, G; Supuran, CT Carbonic anhydrase inhibitors: crystallographic and solution binding studies for the interaction of a boron-containing aromatic sulfamide with mammalian isoforms I-XV. Bioorg Med Chem Lett20:3601-5 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 13 |
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| Name: | Carbonic anhydrase 13 |
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| Synonyms: | CA-XIII | CAH13_MOUSE | Ca13 | Car13 | Carbonate dehydratase XIII | Carbonic anhydrase 13 | Carbonic anhydrase XIII |
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| Type: | Enzyme |
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| Mol. Mass.: | 29522.80 |
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| Organism: | Mus musculus (mouse) |
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| Description: | Murine cloned isozyme |
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| Residue: | 262 |
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| Sequence: | MARLSWGYGEHNGPIHWNELFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPASAKII
SNSGHSFNVDFDDTEDKSVLRGGPLTGNYRLRQFHLHWGSADDHGSEHVVDGVRYAAELH
VVHWNSDKYPSFVEAAHESDGLAVLGVFLQIGEHNPQLQKITDILDSIKEKGKQTRFTNF
DPLCLLPSSWDYWTYPGSLTVPPLLESVTWIVLKQPISISSQQLARFRSLLCTAEGESAA
FLLSNHRPPQPLKGRRVRASFY
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| BDBM50167367 |
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| n/a |
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| Name | BDBM50167367 |
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| Synonyms: | (4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenylsulfamide | CHEMBL190447 | N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]aminosulfonamide | N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]sulfamide |
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| Type | Small organic molecule |
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| Emp. Form. | C12H19BN2O4S |
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| Mol. Mass. | 298.166 |
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| SMILES | CC1(C)OB(OC1(C)C)c1ccc(NS(N)(=O)=O)cc1 |
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| Structure | 
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