Ki Summary

Reaction Details

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Target

Disks large homolog 4

Ligand

BDBM50339547

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_736707 (CHEMBL1695088)

1800±n/a nM

Citation

Bach, A; Eildal, JN; Stuhr-Hansen, N; Deeskamp, R; Gottschalk, M; Pedersen, SW; Kristensen, AS; Strømgaard, K Cell-permeable and plasma-stable peptidomimetic inhibitors of the postsynaptic density-95/N-methyl-D-aspartate receptor interaction. J Med Chem54:1333-46 (2011) [PubMed] Article

More Info.:

Get all data from this article, Assay Method

Disks large homolog 4

Name:

Disks large homolog 4

Synonyms:

DLG4 | DLG4_HUMAN | PSD95

Type:

PROTEIN

Mol. Mass.:

80483.80

Organism:

Homo sapiens (Human)

Description:

ChEMBL_736705

Residue:

724

Sequence:

MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGE
MEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFV
NEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGN
QHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVY
LKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKD
LLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQIL
SVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGT
ASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDASDEEWWQARRVHSDS
ETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIIL
GPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIE
AGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLE
INKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPA
RERL

BDBM50339547

n/a

Name

BDBM50339547

Synonyms:

(2S,5S,8S,11S)-11-(2-carboxyethyl)-5-(carboxymethyl)-8-((R)-1-hydroxyethyl)-2-isopropyl-14-(naphthalen-2-yl)-4,7,10-trioxo-3,6,9,12-tetraazatetradecan-1-oic acid | CHEMBL1688611

Type

Small organic molecule

Emp. Form.

C30H40N4O10

Mol. Mass.

616.6594

SMILES

CC(C)[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NCCc1ccc2ccccc2c1)[C@@H](C)O)C(O)=O |r|

Structure