| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 3A |
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| Ligand | BDBM50379020 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_809641 (CHEMBL2015860) |
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| Ki | 132±n/a nM |
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| Citation |  Cappelli, A; Manini, M; Paolino, M; Gallelli, A; Anzini, M; Mennuni, L; Del Cadia, M; De Rienzo, F; Menziani, MC; Vomero, S Bivalent Ligands for the Serotonin 5-HT3 Receptor. ACS Med Chem Lett2:571-576 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 3A |
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| Name: | 5-hydroxytryptamine receptor 3A |
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| Synonyms: | 5-HT3 | 5-hydroxytryptamine receptor 3A | 5HT3A_RAT | 5ht3 | Htr3 | Htr3a | Serotonin (5-HT) receptor | Zacopride site-R |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 55428.70 |
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| Organism: | RAT |
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| Description: | 5-HT3 HTR3A RAT::P35563 |
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| Residue: | 483 |
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| Sequence: | MPLCIPQVLLALFLSVLIAQGEGSRRRATQAHSTTQPALLRLSDHLLANYKKGVRPVRDW
RKPTLVSIDVIMYAILNVDEKNQVLTTYIWYRQFWTDEFLQWTPEDFDNVTKLSIPTDSI
WVPDILINEFVDVGKSPSIPYVYVHHQGEVQNYKPLQLVTACSLDIYNFPFDVQNCSLTF
TSWLHTIQDINISLWRTPEEVRSDKSIFINQGEWELLGVFTKFQEFSIETSNSYAEMKFY
VVIRRRPLFYAVSLLLPSIFLMVVDIVGFCLPPDSGERVSFKITLLLGYSVFLIIVSDTL
PATAIGTPLIGVYFVVCMALLVISLAETIFIVQLVHKQDLQRPVPDWLRHLVLDRIAWLL
CLGEQPMAHRPPATFQANKTDDCSAMGNHCSHVGSPQDLEKTSRSRDSPLPPPREASLAV
RGLLQELSSIRHSLEKRDEMREVARDWLRVGYVLDRLLFRIYLLAVLAYSITLVTLWSIW
HYS
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| BDBM50379020 |
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| n/a |
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| Name | BDBM50379020 |
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| Synonyms: | CHEMBL2011598 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H41N5O5 |
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| Mol. Mass. | 515.6449 |
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| SMILES | CN1CCN(CC1)c1nc2ccccc2c(C(=O)NCCOCCOCCNC(=O)OC(C)(C)C)c1C |
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| Structure | 
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