| Reaction Details |
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 | Report a problem with these data |
| Target | DNA polymerase beta |
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| Ligand | BDBM50379292 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_811410 (CHEMBL2013668) |
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| IC50 | >200000±n/a nM |
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| Citation |  Myobatake, Y; Takeuchi, T; Kuramochi, K; Kuriyama, I; Ishido, T; Hirano, K; Sugawara, F; Yoshida, H; Mizushina, Y Pinophilins A and B, inhibitors of mammalian A-, B-, and Y-family DNA polymerases and human cancer cell proliferation. J Nat Prod75:135-41 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| DNA polymerase beta |
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| Name: | DNA polymerase beta |
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| Synonyms: | DNA Polymerase beta | DPOLB_RAT | Polb |
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| Type: | PROTEIN |
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| Mol. Mass.: | 38334.34 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1361926 |
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| Residue: | 335 |
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| Sequence: | MSKRKAPQETLNGGITDMLVELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAK
KLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVTGIGPSAARKLVDEGIK
TLEDLRKNEDKLNHHQRIGLKYFEDFEKRIPREEMLQMQDIVLNEVKKLDPEYIATVCGS
FRRGAESSGDMDVLLTHPNFTSESSKQPKLLHRVVEQLQKVRFITDTLSKGETKFMGVCQ
LPSENDENEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRP
LGVTGVAGEPLPVDSEQDIFDYIQWRYREPKDRSE
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| BDBM50379292 |
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| n/a |
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| Name | BDBM50379292 |
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| Synonyms: | CHEMBL2011646 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H22O7 |
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| Mol. Mass. | 386.3952 |
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| SMILES | C\C=C\C1=CC2=CC(=O)[C@@](C)(OC(=O)c3c(C)cc(O)cc3O)[C@@H](O)[C@@H]2CO1 |r,t:3,5| |
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| Structure | 
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