| Reaction Details |
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 | Report a problem with these data |
| Target | DNA-directed DNA polymerase |
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| Ligand | BDBM50379294 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_811421 (CHEMBL2013679) |
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| IC50 | >200000±n/a nM |
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| Citation |  Myobatake, Y; Takeuchi, T; Kuramochi, K; Kuriyama, I; Ishido, T; Hirano, K; Sugawara, F; Yoshida, H; Mizushina, Y Pinophilins A and B, inhibitors of mammalian A-, B-, and Y-family DNA polymerases and human cancer cell proliferation. J Nat Prod75:135-41 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| DNA-directed DNA polymerase |
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| Name: | DNA-directed DNA polymerase |
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| Synonyms: | 43 | DNA polymerase | DPOL_BPT4 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 103605.06 |
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| Organism: | Enterobacteria phage T4 |
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| Description: | ChEMBL_1297307 |
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| Residue: | 898 |
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| Sequence: | MKEFYISIETVGNNIVERYIDENGKERTREVEYLPTMFRHCKEESKYKDIYGKNCAPQKF
PSMKDARDWMKRMEDIGLEALGMNDFKLAYISDTYGSEIVYDRKFVRVANCDIEVTGDKF
PDPMKAEYEIDAITHYDSIDDRFYVFDLLNSMYGSVSKWDAKLAAKLDCEGGDEVPQEIL
DRVIYMPFDNERDMLMEYINLWEQKRPAIFTGWNIEGFDVPYIMNRVKMILGERSMKRFS
PIGRVKSKLIQNMYGSKEIYSIDGVSILDYLDLYKKFAFTNLPSFSLESVAQHETKKGKL
PYDGPINKLRETNHQRYISYNIIDVESVQAIDKIRGFIDLVLSMSYYAKMPFSGVMSPIK
TWDAIIFNSLKGEHKVIPQQGSHVKQSFPGAFVFEPKPIARRYIMSFDLTSLYPSIIRQV
NISPETIRGQFKVHPIHEYIAGTAPKPSDEYSCSPNGWMYDKHQEGIIPKEIAKVFFQRK
DWKKKMFAEEMNAEAIKKIIMKGAGSCSTKPEVERYVKFSDDFLNELSNYTESVLNSLIE
ECEKAATLANTNQLNRKILINSLYGALGNIHFRYYDLRNATAITIFGQVGIQWIARKINE
YLNKVCGTNDEDFIAAGDTDSVYVCVDKVIEKVGLDRFKEQNDLVEFMNQFGKKKMEPMI
DVAYRELCDYMNNREHLMHMDREAISCPPLGSKGVGGFWKAKKRYALNVYDMEDKRFAEP
HLKIMGMETQQSSTPKAVQEALEESIRRILQEGEESVQEYYKNFEKEYRQLDYKVIAEVK
TANDIAKYDDKGWPGFKCPFHIRGVLTYRRAVSGLGVAPILDGNKVMVLPLREGNPFGDK
CIAWPSGTELPKEIRSDVLSWIDHSTLFQKSFVKPLAGMCESAGMDYEEKASLDFLFG
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| BDBM50379294 |
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| n/a |
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| Name | BDBM50379294 |
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| Synonyms: | CHEMBL2011647 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H22O8 |
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| Mol. Mass. | 402.3946 |
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| SMILES | Cc1cc(O)cc(O)c1C(=O)O[C@H]1[C@@H]2COC(\C=C\CO)=CC2=CC(=O)[C@@]1(C)O |r,c:21,24| |
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| Structure | 
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