Reaction Details | |||
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Target | Neuropeptide Y receptor type 5 | ||
Ligand | BDBM50379608 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_811654 (CHEMBL2014167) | ||
Ki | 0.3±n/a nM | ||
Citation | Wu, L; Lu, K; Packiarajan, M; Jubian, V; Chandrasena, G; Wolinsky, TC; Walker, MW Indolyl and dihydroindolyl N-glycinamides as potent and in vivo active NPY5 antagonists. Bioorg Med Chem Lett22:2167-71 (2012) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Neuropeptide Y receptor type 5 | |||
Name: | Neuropeptide Y receptor type 5 | ||
Synonyms: | NPY-Y5 | NPY-Y5 receptor | NPY5-R | NPY5R | NPY5R_HUMAN | NPYR5 | NPYY5 | Neuropeptide Y receptor type 5 | Neuropeptide Y receptor type 5 ( NPY Y5) | Y5 receptor | ||
Type: | Enzyme | ||
Mol. Mass.: | 50746.64 | ||
Organism: | Homo sapiens (Human) | ||
Description: | Q15761 | ||
Residue: | 445 | ||
Sequence: |
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BDBM50379608 | |||
n/a | |||
Name | BDBM50379608 | ||
Synonyms: | CHEMBL2013020 | ||
Type | Small organic molecule | ||
Emp. Form. | C20H28ClN3O3S | ||
Mol. Mass. | 425.973 | ||
SMILES | CC(C)S(=O)(=O)NC[C@H]1CC[C@@H](CC1)NC(=O)Cn1ccc2cc(Cl)ccc12 |r,wU:8.7,wD:11.14,(12.87,-43.9,;11.53,-43.13,;11.53,-41.59,;10.2,-43.89,;10.96,-45.22,;9.43,-45.22,;8.86,-43.13,;7.53,-43.9,;6.2,-43.12,;4.87,-43.89,;3.54,-43.12,;3.54,-41.58,;4.87,-40.8,;6.2,-41.58,;2.2,-40.82,;.87,-41.59,;.88,-43.13,;-.46,-40.82,;-1.8,-41.6,;-1.96,-43.13,;-3.47,-43.45,;-4.24,-42.12,;-5.74,-41.81,;-6.22,-40.35,;-7.73,-40.04,;-5.19,-39.2,;-3.68,-39.52,;-3.21,-40.98,)| | ||
Structure |