| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Oxytocin receptor |
|---|
| Ligand | BDBM50380760 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_813470 (CHEMBL2019478) |
|---|
| Ki | 28±n/a nM |
|---|
| Citation |  Smith, AL; Freeman, SM; Stehouwer, JS; Inoue, K; Voll, RJ; Young, LJ; Goodman, MM Synthesis and evaluation of C-11, F-18 and I-125 small molecule radioligands for detecting oxytocin receptors. Bioorg Med Chem20:2721-38 (2012) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Oxytocin receptor |
|---|
| Name: | Oxytocin receptor |
|---|
| Synonyms: | OT-R | OXTR | OXYR_HUMAN | Oxytocin |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 42793.26 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Oxytocin OXTR HEK293::B2R9L7 |
|---|
| Residue: | 389 |
|---|
| Sequence: | MEGALAANWSAEAANASAAPPGAEGNRTAGPPRRNEALARVEVAVLCLILLLALSGNACV
LLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQV
VGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLATWLGCLVASAPQVHIFSLREV
ADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAA
AEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVW
DANAPKEASAFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSASYLKGRRLGET
SASKKSNSSSFVLSHRSSSQRSCSQPSTA
|
|
|
|---|
| BDBM50380760 |
|---|
| n/a |
|---|
| Name | BDBM50380760 |
|---|
| Synonyms: | CHEMBL2017979 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C29H37N3O6S |
|---|
| Mol. Mass. | 555.686 |
|---|
| SMILES | COc1cc(OC2CCN(CC2)S(C)(=O)=O)ccc1CC(=O)N1CCC(CC1)N1C(=O)CCc2ccccc12 |
|---|
| Structure | 
|
|---|
Search and Browse
