| Reaction Details |
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 | Report a problem with these data |
| Target | Acetylcholinesterase |
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| Ligand | BDBM50029799 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_813756 (CHEMBL2020014) |
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| IC50 | 23700±n/a nM |
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| Citation |  Khorana, N; Changwichit, K; Ingkaninan, K; Utsintong, M Prospective acetylcholinesterase inhibitory activity of indole and its analogs. Bioorg Med Chem Lett22:2885-8 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Acetylcholinesterase |
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| Name: | Acetylcholinesterase |
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| Synonyms: | ACES_HUMAN | ACHE | Acetylcholinesterase (AChE) | Acetylcholinesterase (human AChE) |
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| Type: | Enzyme |
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| Mol. Mass.: | 67792.70 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P22303 |
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| Residue: | 614 |
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| Sequence: | MRPPQCLLHTPSLASPLLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRGIRLKTPGGPV
SAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPN
RELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSM
NYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASV
GMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTEL
VACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVG
VVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPE
DPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGY
EIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQ
YVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKN
QFDHYSKQDRCSDL
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| BDBM50029799 |
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| n/a |
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| Name | BDBM50029799 |
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| Synonyms: | 7-Methoxy-1-methyl-2,9-dihydro-1H-beta-carboline | 7-Methoxy-1-methyl-4,9-dihydro-3H-beta-carboline | 7-methoxy-1-methyl-4,9-dihydro-3H-pyrido[3,4-b]indole | CHEMBL2089157 | CHEMBL340807 | HARMALINE |
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| Type | Small organic molecule |
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| Emp. Form. | C13H14N2O |
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| Mol. Mass. | 214.2631 |
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| SMILES | COc1ccc2c3CCN=C(C)c3[nH]c2c1 |t:9| |
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| Structure | 
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