| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 5B, mitochondrial |
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| Ligand | BDBM23926 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_814450 (CHEMBL2019846) |
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| Ki | 3240±n/a nM |
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| Citation |  Balboni, G; Congiu, C; Onnis, V; Maresca, A; Scozzafava, A; Winum, JY; Maietti, A; Supuran, CT Flavones and structurally related 4-chromenones inhibit carbonic anhydrases by a different mechanism of action compared to coumarins. Bioorg Med Chem Lett22:3063-6 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 5B, mitochondrial |
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| Name: | Carbonic anhydrase 5B, mitochondrial |
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| Synonyms: | CA-VB | CA5B | CAH5B_HUMAN | Carbonate dehydratase VB | Carbonic Anhydrase VB | Carbonic anhydrase 5B (CA VB) | Carbonic anhydrase 5B, mitochondrial | Carbonic anhydrase 5B, mitochondrial precursor | Carbonic anhydrase V | Carbonic anhydrase VB (CA VB) |
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| Type: | Enzyme |
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| Mol. Mass.: | 36440.83 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human (cloned) isozyme |
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| Residue: | 317 |
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| Sequence: | MVVMNSLRVILQASPGKLLWRKFQIPRFMPARPCSLYTCTYKTRNRALHPLWESVDLVPG
GDRQSPINIRWRDSVYDPGLKPLTISYDPATCLHVWNNGYSFLVEFEDSTDKSVIKGGPL
EHNYRLKQFHFHWGAIDAWGSEHTVDSKCFPAELHLVHWNAVRFENFEDAALEENGLAVI
GVFLKLGKHHKELQKLVDTLPSIKHKDALVEFGSFDPSCLMPTCPDYWTYSGSLTTPPLS
ESVTWIIKKQPVEVDHDQLEQFRTLLFTSEGEKEKRMVDNFRPLQPLMNRTVRSSFRHDY
VLNVQAKPKPATSQATP
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| BDBM23926 |
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| n/a |
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| Name | BDBM23926 |
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| Synonyms: | (E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol | CHEMBL165 | Resveratol | Stilbene, 2f | US11866416, Example 7 | cid_445154 | resveratrol | trans-resveratrol |
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| Type | Small organic molecule |
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| Emp. Form. | C14H12O3 |
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| Mol. Mass. | 228.2433 |
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| SMILES | Oc1ccc(\C=C\c2cc(O)cc(O)c2)cc1 |
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| Structure | 
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