| Reaction Details |
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 | Report a problem with these data |
| Target | Histone deacetylase-like amidohydrolase |
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| Ligand | BDBM50386452 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_827139 (CHEMBL2050423) |
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| IC50 | 32000±n/a nM |
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| Citation |  Baud, MG; Leiser, T; Haus, P; Samlal, S; Wong, AC; Wood, RJ; Petrucci, V; Gunaratnam, M; Hughes, SM; Buluwela, L; Turlais, F; Neidle, S; Meyer-Almes, FJ; White, AJ; Fuchter, MJ Defining the mechanism of action and enzymatic selectivity of psammaplin A against its epigenetic targets. J Med Chem55:1731-50 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone deacetylase-like amidohydrolase |
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| Name: | Histone deacetylase-like amidohydrolase |
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| Synonyms: | HDAH_ALCSD | hdaH | hdaH1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 39419.78 |
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| Organism: | Alcaligenes sp. (strain DSM 11172) (Bordetella sp. (strain FB188)) |
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| Description: | ChEMBL_827139 |
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| Residue: | 369 |
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| Sequence: | MAIGYVWNTLYGWVDTGTGSLAAANLTARMQPISHHLAHPDTKRRFHELVCASGQIEHLT
PIAAVAATDADILRAHSAAHLENMKRVSNLPTGGDTGDGITMMGNGGLEIARLSAGGAVE
LTRRVATGELSAGYALVNPPGHHAPHNAAMGFCIFNNTSVAAGYARAVLGMERVAILDWD
VHHGNGTQDIWWNDPSVLTISLHQHLCFPPDSGYSTERGAGNGHGYNINVPLPPGSGNAA
YLHAMDQVVLHALRAYRPQLIIVGSGFDASMLDPLARMMVTADGFRQMARRTIDCAADIC
DGRIVFVQEGGYSPHYLPFCGLAVIEELTGVRSLPDPYHEFLAGMGGNTLLDAERAAIEE
IVPLLADIR
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| BDBM50386452 |
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| n/a |
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| Name | BDBM50386452 |
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| Synonyms: | CHEMBL2047680 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H14BrN3O2S |
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| Mol. Mass. | 332.217 |
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| SMILES | NN=C(Cc1ccc(O)c(Br)c1)C(=O)NCCS |w:1.0| |
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| Structure | 
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