| Reaction Details |
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 | Report a problem with these data |
| Target | Histone-arginine methyltransferase CARM1 |
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| Ligand | BDBM50387477 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_828321 (CHEMBL2050395) |
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| IC50 | 100000±n/a nM |
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| Citation |  Sinha, SH; Owens, EA; Feng, Y; Yang, Y; Xie, Y; Tu, Y; Henary, M; Zheng, YG Synthesis and evaluation of carbocyanine dyes as PRMT inhibitors and imaging agents. Eur J Med Chem54:647-59 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone-arginine methyltransferase CARM1 |
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| Name: | Histone-arginine methyltransferase CARM1 |
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| Synonyms: | CARM1 | CARM1_HUMAN | Coactivator-associated arginine methyltransferase 1 | Coactivator-associated arginine methyltransferase 1 (CARM1) | PRMT4 | Protein arginine N-methyltransferase 4 | Protein arginine methyltransferase 4 (PRMT4) |
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| Type: | Protein |
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| Mol. Mass.: | 65855.47 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q86X55 |
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| Residue: | 608 |
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| Sequence: | MAAAAAAVGPGAGGAGSAVPGGAGPCATVSVFPGARLLTIGDANGEIQRHAEQQALRLEV
RAGPDSAGIALYSHEDVCVFKCSVSRETECSRVGKQSFIITLGCNSVLIQFATPNDFCSF
YNILKTCRGHTLERSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNH
TDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPG
KVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKKYLKPSGNMFPTIGDVHLAPFTDE
QLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFL
EAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRC
LFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYTGTT
PSPPPGSHYTSPSENMWNTGSTYNLSSGMAVAGMPTAYDLSSVIASGSSVGHNNLIPLAN
TGIVNHTHSRMGSIMSTGIVQGSSGAQGSGGGSTSAHYAVNSQFTMGGPAISMASPMSIP
TNTMHYGS
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| BDBM50387477 |
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| n/a |
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| Name | BDBM50387477 |
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| Synonyms: | CHEMBL2047477 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H25N2 |
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| Mol. Mass. | 401.5217 |
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| SMILES | CCn1c2cccc3cccc(c23)\c1=C\[CH+]\C=c1/n(CC)c2cccc3cccc1c23 |
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| Structure | 
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