| Reaction Details |
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 | Report a problem with these data |
| Target | Long-chain fatty acid transport protein 1 |
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| Ligand | BDBM50387689 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_830658 (CHEMBL2061593) |
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| IC50 | >1000±n/a nM |
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| Citation |  Matsufuji, T; Ikeda, M; Naito, A; Hirouchi, M; Takakusa, H; Kanda, S; Izumi, M; Harada, J; Shinozuka, T Discovery and optimization of novel fatty acid transport protein 1 (FATP1) inhibitors. Bioorg Med Chem Lett22:5067-70 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Long-chain fatty acid transport protein 1 |
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| Name: | Long-chain fatty acid transport protein 1 |
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| Synonyms: | 6.2.1.- | ACSVL5 | FATP-1 | FATP1 | Fatty acid transport protein 1 | S27A1_HUMAN | SLC27A1 | Solute carrier family 27 member 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 71123.97 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_956920 |
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| Residue: | 646 |
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| Sequence: | MRAPGAGAASVVSLALLWLLGLPWTWSAAAALGVYVGSGGWRFLRIVCKTARRDLFGLSV
LIRVRLELRRHQRAGHTIPRIFQAVVQRQPERLALVDAGTGECWTFAQLDAYSNAVANLF
RQLGFAPGDVVAIFLEGRPEFVGLWLGLAKAGMEAALLNVNLRREPLAFCLGTSGAKALI
FGGEMVAAVAEVSGHLGKSLIKFCSGDLGPEGILPDTHLLDPLLKEASTAPLAQIPSKGM
DDRLFYIYTSGTTGLPKAAIVVHSRYYRMAAFGHHAYRMQAADVLYDCLPLYHSAGNIIG
VGQCLIYGLTVVLRKKFSASRFWDDCIKYNCTVVQYIGEICRYLLKQPVREAERRHRVRL
AVGNGLRPAIWEEFTERFGVRQIGEFYGATECNCSIANMDGKVGSCGFNSRILPHVYPIR
LVKVNEDTMELLRDAQGLCIPCQAGEPGLLVGQINQQDPLRRFDGYVSESATSKKIAHSV
FSKGDSAYLSGDVLVMDELGYMYFRDRSGDTFRWRGENVSTTEVEGVLSRLLGQTDVAVY
GVAVPGVEGKAGMAAVADPHSLLDPNAIYQELQKVLAPYARPIFLRLLPQVDTTGTFKIQ
KTRLQREGFDPRQTSDRLFFLDLKQGHYLPLNEAVYTRICSGAFAL
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| BDBM50387689 |
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| n/a |
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| Name | BDBM50387689 |
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| Synonyms: | CHEMBL2058353 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H21N5OS |
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| Mol. Mass. | 379.479 |
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| SMILES | CCn1c(CNc2ccccc2)nnc1SCc1nc2cc(C)ccc2o1 |
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| Structure | 
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