Found 99 hits with Last Name = 'takakusa' and Initial = 'h' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Hormone-sensitive lipase
(Homo sapiens (Human)) | BDBM50233398
(CHEMBL4063082)Show SMILES OB(O)c1cc(Cl)ccc1NC(=O)c1ccc(Oc2ccc(cc2)C(F)(F)F)nc1 Show InChI InChI=1S/C19H13BClF3N2O4/c21-13-4-7-16(15(9-13)20(28)29)26-18(27)11-1-8-17(25-10-11)30-14-5-2-12(3-6-14)19(22,23)24/h1-10,28-29H,(H,26,27) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human HSL expressed in baculovirus infected sf9 cells using PNPB as substrate after 5 mins by spectrophotometric method |
Bioorg Med Chem 25: 2234-2243 (2017)
Article DOI: 10.1016/j.bmc.2017.02.045
BindingDB Entry DOI: 10.7270/Q2VH5R3W |
More data for this
Ligand-Target Pair | |
Hormone-sensitive lipase
(Homo sapiens (Human)) | BDBM50233399
(CHEMBL4101186)Show SMILES CC1(C)OB(OC1(C)C)c1cc(Cl)ccc1NC(=O)c1ccc(Oc2ccc(cc2)C(F)(F)F)nc1 Show InChI InChI=1S/C25H23BClF3N2O4/c1-23(2)24(3,4)36-26(35-23)19-13-17(27)8-11-20(19)32-22(33)15-5-12-21(31-14-15)34-18-9-6-16(7-10-18)25(28,29)30/h5-14H,1-4H3,(H,32,33) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human HSL expressed in baculovirus infected sf9 cells using PNPB as substrate after 5 mins by spectrophotometric method |
Bioorg Med Chem 25: 2234-2243 (2017)
Article DOI: 10.1016/j.bmc.2017.02.045
BindingDB Entry DOI: 10.7270/Q2VH5R3W |
More data for this
Ligand-Target Pair | |
Hormone-sensitive lipase
(Homo sapiens (Human)) | BDBM50233409
(CHEMBL4084740)Show SMILES OB(O)c1cc(F)ccc1NC(=O)c1ccc(Oc2ccc(cc2)C(F)(F)F)nc1 Show InChI InChI=1S/C19H13BF4N2O4/c21-13-4-7-16(15(9-13)20(28)29)26-18(27)11-1-8-17(25-10-11)30-14-5-2-12(3-6-14)19(22,23)24/h1-10,28-29H,(H,26,27) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human HSL expressed in baculovirus infected sf9 cells using PNPB as substrate after 5 mins by spectrophotometric method |
Bioorg Med Chem 25: 2234-2243 (2017)
Article DOI: 10.1016/j.bmc.2017.02.045
BindingDB Entry DOI: 10.7270/Q2VH5R3W |
More data for this
Ligand-Target Pair | |
Hormone-sensitive lipase
(Homo sapiens (Human)) | BDBM50233412
(CHEMBL4093111)Show SMILES CC1(C)OB(OC1(C)C)c1ccccc1NC(=O)c1ccc(Oc2ccc(cc2)C(F)(F)F)nc1 Show InChI InChI=1S/C25H24BF3N2O4/c1-23(2)24(3,4)35-26(34-23)19-7-5-6-8-20(19)31-22(32)16-9-14-21(30-15-16)33-18-12-10-17(11-13-18)25(27,28)29/h5-15H,1-4H3,(H,31,32) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human HSL expressed in baculovirus infected sf9 cells using PNPB as substrate after 5 mins by spectrophotometric method |
Bioorg Med Chem 25: 2234-2243 (2017)
Article DOI: 10.1016/j.bmc.2017.02.045
BindingDB Entry DOI: 10.7270/Q2VH5R3W |
More data for this
Ligand-Target Pair | |
Hormone-sensitive lipase
(Homo sapiens (Human)) | BDBM50233410
(CHEMBL4100232)Show SMILES OB(O)c1ccc(F)cc1NC(=O)c1ccc(Oc2ccc(cc2)C(F)(F)F)nc1 Show InChI InChI=1S/C19H13BF4N2O4/c21-13-4-7-15(20(28)29)16(9-13)26-18(27)11-1-8-17(25-10-11)30-14-5-2-12(3-6-14)19(22,23)24/h1-10,28-29H,(H,26,27) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human HSL expressed in baculovirus infected sf9 cells using PNPB as substrate after 5 mins by spectrophotometric method |
Bioorg Med Chem 25: 2234-2243 (2017)
Article DOI: 10.1016/j.bmc.2017.02.045
BindingDB Entry DOI: 10.7270/Q2VH5R3W |
More data for this
Ligand-Target Pair | |
Hormone-sensitive lipase
(Homo sapiens (Human)) | BDBM50233397
(CHEMBL4074445)Show SMILES Cc1ccc(NC(=O)c2ccc(Oc3ccc(cc3)C(F)(F)F)nc2)c(c1)B(O)O Show InChI InChI=1S/C20H16BF3N2O4/c1-12-2-8-17(16(10-12)21(28)29)26-19(27)13-3-9-18(25-11-13)30-15-6-4-14(5-7-15)20(22,23)24/h2-11,28-29H,1H3,(H,26,27) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human HSL expressed in baculovirus infected sf9 cells using PNPB as substrate after 5 mins by spectrophotometric method |
Bioorg Med Chem 25: 2234-2243 (2017)
Article DOI: 10.1016/j.bmc.2017.02.045
BindingDB Entry DOI: 10.7270/Q2VH5R3W |
More data for this
Ligand-Target Pair | |
Hormone-sensitive lipase
(Homo sapiens (Human)) | BDBM50233407
(CHEMBL4100819)Show SMILES CC1(C)OB(OC1(C)C)c1ccccc1NC(=O)c1ccc(Oc2cccc(OC(F)(F)F)c2)nc1 Show InChI InChI=1S/C25H24BF3N2O5/c1-23(2)24(3,4)36-26(35-23)19-10-5-6-11-20(19)31-22(32)16-12-13-21(30-15-16)33-17-8-7-9-18(14-17)34-25(27,28)29/h5-15H,1-4H3,(H,31,32) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human HSL expressed in baculovirus infected sf9 cells using PNPB as substrate after 5 mins by spectrophotometric method |
Bioorg Med Chem 25: 2234-2243 (2017)
Article DOI: 10.1016/j.bmc.2017.02.045
BindingDB Entry DOI: 10.7270/Q2VH5R3W |
More data for this
Ligand-Target Pair | |
Hormone-sensitive lipase
(Homo sapiens (Human)) | BDBM50233400
(CHEMBL4082218)Show SMILES OB(O)c1ccc(Cl)cc1NC(=O)c1ccc(Oc2ccc(cc2)C(F)(F)F)nc1 Show InChI InChI=1S/C19H13BClF3N2O4/c21-13-4-7-15(20(28)29)16(9-13)26-18(27)11-1-8-17(25-10-11)30-14-5-2-12(3-6-14)19(22,23)24/h1-10,28-29H,(H,26,27) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human HSL expressed in baculovirus infected sf9 cells using PNPB as substrate after 5 mins by spectrophotometric method |
Bioorg Med Chem 25: 2234-2243 (2017)
Article DOI: 10.1016/j.bmc.2017.02.045
BindingDB Entry DOI: 10.7270/Q2VH5R3W |
More data for this
Ligand-Target Pair | |
Hormone-sensitive lipase
(Homo sapiens (Human)) | BDBM50233406
(CHEMBL4082836)Show SMILES CC1(C)OB(OC1(C)C)c1ccccc1NC(=O)c1ccc(Oc2ccc(OC(F)(F)F)cc2)nc1 Show InChI InChI=1S/C25H24BF3N2O5/c1-23(2)24(3,4)36-26(35-23)19-7-5-6-8-20(19)31-22(32)16-9-14-21(30-15-16)33-17-10-12-18(13-11-17)34-25(27,28)29/h5-15H,1-4H3,(H,31,32) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human HSL expressed in baculovirus infected sf9 cells using PNPB as substrate after 5 mins by spectrophotometric method |
Bioorg Med Chem 25: 2234-2243 (2017)
Article DOI: 10.1016/j.bmc.2017.02.045
BindingDB Entry DOI: 10.7270/Q2VH5R3W |
More data for this
Ligand-Target Pair | |
Hormone-sensitive lipase
(Homo sapiens (Human)) | BDBM50233408
(CHEMBL4090644)Show SMILES CN(c1ccc(OC(F)(F)F)cc1)c1ccc(cn1)C(=O)Nc1ccccc1B1OC(C)(C)C(C)(C)O1 Show InChI InChI=1S/C26H27BF3N3O4/c1-24(2)25(3,4)37-27(36-24)20-8-6-7-9-21(20)32-23(34)17-10-15-22(31-16-17)33(5)18-11-13-19(14-12-18)35-26(28,29)30/h6-16H,1-5H3,(H,32,34) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human HSL expressed in baculovirus infected sf9 cells using PNPB as substrate after 5 mins by spectrophotometric method |
Bioorg Med Chem 25: 2234-2243 (2017)
Article DOI: 10.1016/j.bmc.2017.02.045
BindingDB Entry DOI: 10.7270/Q2VH5R3W |
More data for this
Ligand-Target Pair | |
Hormone-sensitive lipase
(Homo sapiens (Human)) | BDBM50233413
(CHEMBL4062688)Show SMILES OB(O)c1ccccc1NC(=O)c1ccc(Oc2ccc(cc2)C(F)(F)F)nc1 Show InChI InChI=1S/C19H14BF3N2O4/c21-19(22,23)13-6-8-14(9-7-13)29-17-10-5-12(11-24-17)18(26)25-16-4-2-1-3-15(16)20(27)28/h1-11,27-28H,(H,25,26) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human HSL expressed in baculovirus infected sf9 cells using PNPB as substrate after 5 mins by spectrophotometric method |
Bioorg Med Chem 25: 2234-2243 (2017)
Article DOI: 10.1016/j.bmc.2017.02.045
BindingDB Entry DOI: 10.7270/Q2VH5R3W |
More data for this
Ligand-Target Pair | |
Hormone-sensitive lipase
(Homo sapiens (Human)) | BDBM50233401
(CHEMBL4092488)Show SMILES COc1ccc(B(O)O)c(NC(=O)c2ccc(Oc3ccc(cc3)C(F)(F)F)nc2)c1 Show InChI InChI=1S/C20H16BF3N2O5/c1-30-15-7-8-16(21(28)29)17(10-15)26-19(27)12-2-9-18(25-11-12)31-14-5-3-13(4-6-14)20(22,23)24/h2-11,28-29H,1H3,(H,26,27) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 59 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human HSL expressed in baculovirus infected sf9 cells using PNPB as substrate after 5 mins by spectrophotometric method |
Bioorg Med Chem 25: 2234-2243 (2017)
Article DOI: 10.1016/j.bmc.2017.02.045
BindingDB Entry DOI: 10.7270/Q2VH5R3W |
More data for this
Ligand-Target Pair | |
Long-chain fatty acid transport protein 1
(Mus musculus) | BDBM50387683
(CHEMBL2058359)Show SMILES CCn1c(CNc2ccccc2)nnc1SCc1nc2cc(OC(F)(F)F)ccc2o1 Show InChI InChI=1S/C20H18F3N5O2S/c1-2-28-17(11-24-13-6-4-3-5-7-13)26-27-19(28)31-12-18-25-15-10-14(30-20(21,22)23)8-9-16(15)29-18/h3-10,24H,2,11-12H2,1H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 91 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of mouse recombinant FATP1 acyl-coA synthetase activity using [14C]oleic acid as substrate |
Bioorg Med Chem Lett 22: 5067-70 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.130
BindingDB Entry DOI: 10.7270/Q2VD70HW |
More data for this
Ligand-Target Pair | |
Hormone-sensitive lipase
(Homo sapiens (Human)) | BDBM50233403
(CHEMBL4062547)Show SMILES OB(O)c1ccccc1NC(=O)c1ccc(Oc2ccc(cn2)C(F)(F)F)cc1 Show InChI InChI=1S/C19H14BF3N2O4/c21-19(22,23)13-7-10-17(24-11-13)29-14-8-5-12(6-9-14)18(26)25-16-4-2-1-3-15(16)20(27)28/h1-11,27-28H,(H,25,26) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 91 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human HSL expressed in baculovirus infected sf9 cells using PNPB as substrate after 5 mins by spectrophotometric method |
Bioorg Med Chem 25: 2234-2243 (2017)
Article DOI: 10.1016/j.bmc.2017.02.045
BindingDB Entry DOI: 10.7270/Q2VH5R3W |
More data for this
Ligand-Target Pair | |
Long-chain fatty acid transport protein 1
(Homo sapiens (Human)) | BDBM50387683
(CHEMBL2058359)Show SMILES CCn1c(CNc2ccccc2)nnc1SCc1nc2cc(OC(F)(F)F)ccc2o1 Show InChI InChI=1S/C20H18F3N5O2S/c1-2-28-17(11-24-13-6-4-3-5-7-13)26-27-19(28)31-12-18-25-15-10-14(30-20(21,22)23)8-9-16(15)29-18/h3-10,24H,2,11-12H2,1H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant FATP1 acyl-coA synthetase activity using [14C]oleic acid as substrate |
Bioorg Med Chem Lett 22: 5067-70 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.130
BindingDB Entry DOI: 10.7270/Q2VD70HW |
More data for this
Ligand-Target Pair | |
Hormone-sensitive lipase
(Homo sapiens (Human)) | BDBM50233405
(CHEMBL4072344)Show SMILES CC1(C)OB(OC1(C)C)c1ccccc1NC(=O)c1ccc(Oc2ccc(cc2)C(F)(F)F)cn1 Show InChI InChI=1S/C25H24BF3N2O4/c1-23(2)24(3,4)35-26(34-23)19-7-5-6-8-20(19)31-22(32)21-14-13-18(15-30-21)33-17-11-9-16(10-12-17)25(27,28)29/h5-15H,1-4H3,(H,31,32) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human HSL expressed in baculovirus infected sf9 cells using PNPB as substrate after 5 mins by spectrophotometric method |
Bioorg Med Chem 25: 2234-2243 (2017)
Article DOI: 10.1016/j.bmc.2017.02.045
BindingDB Entry DOI: 10.7270/Q2VH5R3W |
More data for this
Ligand-Target Pair | |
Hormone-sensitive lipase
(Homo sapiens (Human)) | BDBM50233402
(CHEMBL4082697)Show SMILES CC1(C)OB(OC1(C)C)c1ccccc1NC(=O)c1ccc(Oc2ccc(cn2)C(F)(F)F)cc1 Show InChI InChI=1S/C25H24BF3N2O4/c1-23(2)24(3,4)35-26(34-23)19-7-5-6-8-20(19)31-22(32)16-9-12-18(13-10-16)33-21-14-11-17(15-30-21)25(27,28)29/h5-15H,1-4H3,(H,31,32) | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human HSL expressed in baculovirus infected sf9 cells using PNPB as substrate after 5 mins by spectrophotometric method |
Bioorg Med Chem 25: 2234-2243 (2017)
Article DOI: 10.1016/j.bmc.2017.02.045
BindingDB Entry DOI: 10.7270/Q2VH5R3W |
More data for this
Ligand-Target Pair | |
Long-chain fatty acid transport protein 1
(Homo sapiens (Human)) | BDBM50387697
(CHEMBL2058343)Show SMILES CCC(=O)c1ccc2oc(CSc3nnc(CNc4ccccc4)n3CC)nc2c1 Show InChI InChI=1S/C22H23N5O2S/c1-3-18(28)15-10-11-19-17(12-15)24-21(29-19)14-30-22-26-25-20(27(22)4-2)13-23-16-8-6-5-7-9-16/h5-12,23H,3-4,13-14H2,1-2H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant FATP1 acyl-coA synthetase activity using [14C]oleic acid as substrate |
Bioorg Med Chem Lett 22: 5067-70 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.130
BindingDB Entry DOI: 10.7270/Q2VD70HW |
More data for this
Ligand-Target Pair | |
Long-chain fatty acid transport protein 1
(Mus musculus) | BDBM50387693
(CHEMBL2058349)Show SMILES CCC(N=O)c1ccc2oc(CSc3nnc(CNc4ccccc4)n3CC)nc2c1 Show InChI InChI=1S/C22H24N6O2S/c1-3-17(27-29)15-10-11-19-18(12-15)24-21(30-19)14-31-22-26-25-20(28(22)4-2)13-23-16-8-6-5-7-9-16/h5-12,17,23H,3-4,13-14H2,1-2H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of mouse recombinant FATP1 acyl-coA synthetase activity using [14C]oleic acid as substrate |
Bioorg Med Chem Lett 22: 5067-70 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.130
BindingDB Entry DOI: 10.7270/Q2VD70HW |
More data for this
Ligand-Target Pair | |
Long-chain fatty acid transport protein 1
(Homo sapiens (Human)) | BDBM50387704
(CHEMBL2058092)Show SMILES CCCC(=O)c1ccc(NC(=O)CSc2nnc(CNc3ccccc3)n2CC)cc1 Show InChI InChI=1S/C23H27N5O2S/c1-3-8-20(29)17-11-13-19(14-12-17)25-22(30)16-31-23-27-26-21(28(23)4-2)15-24-18-9-6-5-7-10-18/h5-7,9-14,24H,3-4,8,15-16H2,1-2H3,(H,25,30) | Reactome pathway
KEGG
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PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant FATP1 acyl-coA synthetase activity using [14C]oleic acid as substrate |
Bioorg Med Chem Lett 22: 5067-70 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.130
BindingDB Entry DOI: 10.7270/Q2VD70HW |
More data for this
Ligand-Target Pair | |
Long-chain fatty acid transport protein 1
(Homo sapiens (Human)) | BDBM50387693
(CHEMBL2058349)Show SMILES CCC(N=O)c1ccc2oc(CSc3nnc(CNc4ccccc4)n3CC)nc2c1 Show InChI InChI=1S/C22H24N6O2S/c1-3-17(27-29)15-10-11-19-18(12-15)24-21(30-19)14-31-22-26-25-20(28(22)4-2)13-23-16-8-6-5-7-9-16/h5-12,17,23H,3-4,13-14H2,1-2H3 | Reactome pathway
KEGG
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PC cid
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UniChem
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PubMed
| n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant FATP1 acyl-coA synthetase activity using [14C]oleic acid as substrate |
Bioorg Med Chem Lett 22: 5067-70 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.130
BindingDB Entry DOI: 10.7270/Q2VD70HW |
More data for this
Ligand-Target Pair | |
Long-chain fatty acid transport protein 1
(Homo sapiens (Human)) | BDBM50387710
(CHEMBL2058076)Show SMILES CCOC(=O)c1ccc(NC(=O)CSc2nnc(CNc3ccccc3)n2CC)cc1 Show InChI InChI=1S/C22H25N5O3S/c1-3-27-19(14-23-17-8-6-5-7-9-17)25-26-22(27)31-15-20(28)24-18-12-10-16(11-13-18)21(29)30-4-2/h5-13,23H,3-4,14-15H2,1-2H3,(H,24,28) | Reactome pathway
KEGG
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PubMed
| n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant FATP1 acyl-coA synthetase activity using [14C]oleic acid as substrate |
Bioorg Med Chem Lett 22: 5067-70 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.130
BindingDB Entry DOI: 10.7270/Q2VD70HW |
More data for this
Ligand-Target Pair | |
Long-chain fatty acid transport protein 1
(Homo sapiens (Human)) | BDBM50387684
(CHEMBL2058358)Show SMILES CCn1c(CNc2ccccc2)nnc1SCc1nc2cc(ccc2o1)C(F)(F)F Show InChI InChI=1S/C20H18F3N5OS/c1-2-28-17(11-24-14-6-4-3-5-7-14)26-27-19(28)30-12-18-25-15-10-13(20(21,22)23)8-9-16(15)29-18/h3-10,24H,2,11-12H2,1H3 | Reactome pathway
KEGG
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PubMed
| n/a | n/a | 360 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant FATP1 acyl-coA synthetase activity using [14C]oleic acid as substrate |
Bioorg Med Chem Lett 22: 5067-70 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.130
BindingDB Entry DOI: 10.7270/Q2VD70HW |
More data for this
Ligand-Target Pair | |
Long-chain fatty acid transport protein 1
(Mus musculus) | BDBM50387684
(CHEMBL2058358)Show SMILES CCn1c(CNc2ccccc2)nnc1SCc1nc2cc(ccc2o1)C(F)(F)F Show InChI InChI=1S/C20H18F3N5OS/c1-2-28-17(11-24-14-6-4-3-5-7-14)26-27-19(28)30-12-18-25-15-10-13(20(21,22)23)8-9-16(15)29-18/h3-10,24H,2,11-12H2,1H3 | Reactome pathway
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UniChem
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| n/a | n/a | 360 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of mouse recombinant FATP1 acyl-coA synthetase activity using [14C]oleic acid as substrate |
Bioorg Med Chem Lett 22: 5067-70 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.130
BindingDB Entry DOI: 10.7270/Q2VD70HW |
More data for this
Ligand-Target Pair | |
Long-chain fatty acid transport protein 1
(Mus musculus) | BDBM50387697
(CHEMBL2058343)Show SMILES CCC(=O)c1ccc2oc(CSc3nnc(CNc4ccccc4)n3CC)nc2c1 Show InChI InChI=1S/C22H23N5O2S/c1-3-18(28)15-10-11-19-17(12-15)24-21(29-19)14-30-22-26-25-20(27(22)4-2)13-23-16-8-6-5-7-9-16/h5-12,23H,3-4,13-14H2,1-2H3 | Reactome pathway
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| n/a | n/a | 360 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of mouse recombinant FATP1 acyl-coA synthetase activity using [14C]oleic acid as substrate |
Bioorg Med Chem Lett 22: 5067-70 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.130
BindingDB Entry DOI: 10.7270/Q2VD70HW |
More data for this
Ligand-Target Pair | |
Hormone-sensitive lipase
(Homo sapiens (Human)) | BDBM50233411
(CHEMBL4075101)Show SMILES Cc1cc(Oc2ccc(cn2)C(F)(F)F)ccc1C(=O)Nc1ccccc1B1OC(C)(C)C(C)(C)O1 Show InChI InChI=1S/C26H26BF3N2O4/c1-16-14-18(34-22-13-10-17(15-31-22)26(28,29)30)11-12-19(16)23(33)32-21-9-7-6-8-20(21)27-35-24(2,3)25(4,5)36-27/h6-15H,1-5H3,(H,32,33) | Reactome pathway
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PubMed
| n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human HSL expressed in baculovirus infected sf9 cells using PNPB as substrate after 5 mins by spectrophotometric method |
Bioorg Med Chem 25: 2234-2243 (2017)
Article DOI: 10.1016/j.bmc.2017.02.045
BindingDB Entry DOI: 10.7270/Q2VH5R3W |
More data for this
Ligand-Target Pair | |
Long-chain fatty acid transport protein 1
(Homo sapiens (Human)) | BDBM50387702
(CHEMBL2058339)Show SMILES CCC(=O)c1ccc(NC(=O)CSc2nnc(CNc3ccccc3)n2CC)cn1 Show InChI InChI=1S/C21H24N6O2S/c1-3-18(28)17-11-10-16(12-23-17)24-20(29)14-30-21-26-25-19(27(21)4-2)13-22-15-8-6-5-7-9-15/h5-12,22H,3-4,13-14H2,1-2H3,(H,24,29) | Reactome pathway
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PubMed
| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant FATP1 acyl-coA synthetase activity using [14C]oleic acid as substrate |
Bioorg Med Chem Lett 22: 5067-70 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.130
BindingDB Entry DOI: 10.7270/Q2VD70HW |
More data for this
Ligand-Target Pair | |
Long-chain fatty acid transport protein 1
(Homo sapiens (Human)) | BDBM50387705
(CHEMBL2058091)Show SMILES CCC(=O)c1ccc(NC(=O)CSc2nnc(CNc3ccccc3)n2CC)cc1 Show InChI InChI=1S/C22H25N5O2S/c1-3-19(28)16-10-12-18(13-11-16)24-21(29)15-30-22-26-25-20(27(22)4-2)14-23-17-8-6-5-7-9-17/h5-13,23H,3-4,14-15H2,1-2H3,(H,24,29) | Reactome pathway
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UniChem
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PubMed
| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant FATP1 acyl-coA synthetase activity using [14C]oleic acid as substrate |
Bioorg Med Chem Lett 22: 5067-70 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.130
BindingDB Entry DOI: 10.7270/Q2VD70HW |
More data for this
Ligand-Target Pair | |
Long-chain fatty acid transport protein 1
(Mus musculus) | BDBM50387681
(CHEMBL2058346)Show SMILES CCn1c(CNc2ccccc2)nnc1SCc1nc2cc(ccc2o1)C(=O)C(C)C Show InChI InChI=1S/C23H25N5O2S/c1-4-28-20(13-24-17-8-6-5-7-9-17)26-27-23(28)31-14-21-25-18-12-16(22(29)15(2)3)10-11-19(18)30-21/h5-12,15,24H,4,13-14H2,1-3H3 | Reactome pathway
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UniChem
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PubMed
| n/a | n/a | 520 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of mouse recombinant FATP1 acyl-coA synthetase activity using [14C]oleic acid as substrate |
Bioorg Med Chem Lett 22: 5067-70 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.130
BindingDB Entry DOI: 10.7270/Q2VD70HW |
More data for this
Ligand-Target Pair | |
Long-chain fatty acid transport protein 1
(Homo sapiens (Human)) | BDBM50387677
(CHEMBL2058078)Show SMILES CCn1c(CNc2ccccc2)nnc1SCC(=O)Nc1ccc(cc1)C(=O)OC Show InChI InChI=1S/C21H23N5O3S/c1-3-26-18(13-22-16-7-5-4-6-8-16)24-25-21(26)30-14-19(27)23-17-11-9-15(10-12-17)20(28)29-2/h4-12,22H,3,13-14H2,1-2H3,(H,23,27) | Reactome pathway
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PubMed
| n/a | n/a | 540 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant FATP1 acyl-coA synthetase activity using [14C]oleic acid as substrate |
Bioorg Med Chem Lett 22: 5067-70 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.130
BindingDB Entry DOI: 10.7270/Q2VD70HW |
More data for this
Ligand-Target Pair | |
Long-chain fatty acid transport protein 1
(Homo sapiens (Human)) | BDBM50387701
(CHEMBL2057220)Show SMILES CCC(=O)c1ccc(cc1)N(C)C(=O)CSc1nnc(CNc2ccccc2)n1CC Show InChI InChI=1S/C23H27N5O2S/c1-4-20(29)17-11-13-19(14-12-17)27(3)22(30)16-31-23-26-25-21(28(23)5-2)15-24-18-9-7-6-8-10-18/h6-14,24H,4-5,15-16H2,1-3H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
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UniChem
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PubMed
| n/a | n/a | 580 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant FATP1 acyl-coA synthetase activity using [14C]oleic acid as substrate |
Bioorg Med Chem Lett 22: 5067-70 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.130
BindingDB Entry DOI: 10.7270/Q2VD70HW |
More data for this
Ligand-Target Pair | |
Long-chain fatty acid transport protein 1
(Homo sapiens (Human)) | BDBM50387681
(CHEMBL2058346)Show SMILES CCn1c(CNc2ccccc2)nnc1SCc1nc2cc(ccc2o1)C(=O)C(C)C Show InChI InChI=1S/C23H25N5O2S/c1-4-28-20(13-24-17-8-6-5-7-9-17)26-27-23(28)31-14-21-25-18-12-16(22(29)15(2)3)10-11-19(18)30-21/h5-12,15,24H,4,13-14H2,1-3H3 | Reactome pathway
KEGG
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UniChem
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PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant FATP1 acyl-coA synthetase activity using [14C]oleic acid as substrate |
Bioorg Med Chem Lett 22: 5067-70 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.130
BindingDB Entry DOI: 10.7270/Q2VD70HW |
More data for this
Ligand-Target Pair | |
Long-chain fatty acid transport protein 1
(Homo sapiens (Human)) | BDBM50387696
(CHEMBL2058344)Show SMILES CCOC(=O)c1ccc2oc(CSc3nnc(CNc4ccccc4)n3CC)nc2c1 Show InChI InChI=1S/C22H23N5O3S/c1-3-27-19(13-23-16-8-6-5-7-9-16)25-26-22(27)31-14-20-24-17-12-15(21(28)29-4-2)10-11-18(17)30-20/h5-12,23H,3-4,13-14H2,1-2H3 | Reactome pathway
KEGG
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UniChem
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PubMed
| n/a | n/a | 680 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant FATP1 acyl-coA synthetase activity using [14C]oleic acid as substrate |
Bioorg Med Chem Lett 22: 5067-70 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.130
BindingDB Entry DOI: 10.7270/Q2VD70HW |
More data for this
Ligand-Target Pair | |
Long-chain fatty acid transport protein 1
(Mus musculus) | BDBM50387696
(CHEMBL2058344)Show SMILES CCOC(=O)c1ccc2oc(CSc3nnc(CNc4ccccc4)n3CC)nc2c1 Show InChI InChI=1S/C22H23N5O3S/c1-3-27-19(13-23-16-8-6-5-7-9-16)25-26-22(27)31-14-20-24-17-12-15(21(28)29-4-2)10-11-18(17)30-20/h5-12,23H,3-4,13-14H2,1-2H3 | Reactome pathway
KEGG
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| n/a | n/a | 840 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of mouse recombinant FATP1 acyl-coA synthetase activity using [14C]oleic acid as substrate |
Bioorg Med Chem Lett 22: 5067-70 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.130
BindingDB Entry DOI: 10.7270/Q2VD70HW |
More data for this
Ligand-Target Pair | |
Long-chain fatty acid transport protein 1
(Homo sapiens (Human)) | BDBM50387695
(CHEMBL2058345)Show SMILES CCC(=O)c1ccc2nc(CSc3nnc(CNc4ccccc4)n3CC)oc2c1 Show InChI InChI=1S/C22H23N5O2S/c1-3-18(28)15-10-11-17-19(12-15)29-21(24-17)14-30-22-26-25-20(27(22)4-2)13-23-16-8-6-5-7-9-16/h5-12,23H,3-4,13-14H2,1-2H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
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UniChem
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PubMed
| n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant FATP1 acyl-coA synthetase activity using [14C]oleic acid as substrate |
Bioorg Med Chem Lett 22: 5067-70 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.130
BindingDB Entry DOI: 10.7270/Q2VD70HW |
More data for this
Ligand-Target Pair | |
Hormone-sensitive lipase
(Homo sapiens (Human)) | BDBM50233404
(CHEMBL4085350)Show SMILES CC1(C)OB(OC1(C)C)c1ccccc1NC(=O)c1ccc(Oc2ccc(cn2)C(F)(F)F)cn1 Show InChI InChI=1S/C24H23BF3N3O4/c1-22(2)23(3,4)35-25(34-22)17-7-5-6-8-18(17)31-21(32)19-11-10-16(14-29-19)33-20-12-9-15(13-30-20)24(26,27)28/h5-14H,1-4H3,(H,31,32) | Reactome pathway
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PubMed
| n/a | n/a | 920 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd.
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human HSL expressed in baculovirus infected sf9 cells using PNPB as substrate after 5 mins by spectrophotometric method |
Bioorg Med Chem 25: 2234-2243 (2017)
Article DOI: 10.1016/j.bmc.2017.02.045
BindingDB Entry DOI: 10.7270/Q2VH5R3W |
More data for this
Ligand-Target Pair | |
Long-chain fatty acid transport protein 1
(Homo sapiens (Human)) | BDBM50387670
(CHEMBL2058085)Show InChI InChI=1S/C19H20ClN5OS/c1-2-25-17(12-21-15-6-4-3-5-7-15)23-24-19(25)27-13-18(26)22-16-10-8-14(20)9-11-16/h3-11,21H,2,12-13H2,1H3,(H,22,26) | Reactome pathway
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| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant FATP1 acyl-coA synthetase activity using [14C]oleic acid as substrate |
Bioorg Med Chem Lett 22: 5067-70 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.130
BindingDB Entry DOI: 10.7270/Q2VD70HW |
More data for this
Ligand-Target Pair | |
Long-chain fatty acid transport protein 1
(Homo sapiens (Human)) | BDBM50387671
(CHEMBL2058084)Show InChI InChI=1S/C19H21N5OS/c1-2-24-17(13-20-15-9-5-3-6-10-15)22-23-19(24)26-14-18(25)21-16-11-7-4-8-12-16/h3-12,20H,2,13-14H2,1H3,(H,21,25) | Reactome pathway
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| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant FATP1 acyl-coA synthetase activity using [14C]oleic acid as substrate |
Bioorg Med Chem Lett 22: 5067-70 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.130
BindingDB Entry DOI: 10.7270/Q2VD70HW |
More data for this
Ligand-Target Pair | |
Long-chain fatty acid transport protein 1
(Homo sapiens (Human)) | BDBM50387672
(CHEMBL2058083)Show SMILES CCNC(=O)c1ccc(NC(=O)CSc2nnc(CNc3ccccc3)n2CC)cc1 Show InChI InChI=1S/C22H26N6O2S/c1-3-23-21(30)16-10-12-18(13-11-16)25-20(29)15-31-22-27-26-19(28(22)4-2)14-24-17-8-6-5-7-9-17/h5-13,24H,3-4,14-15H2,1-2H3,(H,23,30)(H,25,29) | Reactome pathway
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PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant FATP1 acyl-coA synthetase activity using [14C]oleic acid as substrate |
Bioorg Med Chem Lett 22: 5067-70 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.130
BindingDB Entry DOI: 10.7270/Q2VD70HW |
More data for this
Ligand-Target Pair | |
Long-chain fatty acid transport protein 1
(Homo sapiens (Human)) | BDBM50387673
(CHEMBL2058082)Show SMILES CCn1c(CNc2ccccc2)nnc1SCC(=O)Nc1ccc(cc1)C(=O)N(C)C Show InChI InChI=1S/C22H26N6O2S/c1-4-28-19(14-23-17-8-6-5-7-9-17)25-26-22(28)31-15-20(29)24-18-12-10-16(11-13-18)21(30)27(2)3/h5-13,23H,4,14-15H2,1-3H3,(H,24,29) | Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant FATP1 acyl-coA synthetase activity using [14C]oleic acid as substrate |
Bioorg Med Chem Lett 22: 5067-70 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.130
BindingDB Entry DOI: 10.7270/Q2VD70HW |
More data for this
Ligand-Target Pair | |
Long-chain fatty acid transport protein 1
(Homo sapiens (Human)) | BDBM50387674
(CHEMBL2058081)Show SMILES CCn1c(CNc2ccccc2)nnc1SCC(=O)Nc1ccc(cc1)C(=O)NC Show InChI InChI=1S/C21H24N6O2S/c1-3-27-18(13-23-16-7-5-4-6-8-16)25-26-21(27)30-14-19(28)24-17-11-9-15(10-12-17)20(29)22-2/h4-12,23H,3,13-14H2,1-2H3,(H,22,29)(H,24,28) | Reactome pathway
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| CHEMBL
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UniChem
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| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant FATP1 acyl-coA synthetase activity using [14C]oleic acid as substrate |
Bioorg Med Chem Lett 22: 5067-70 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.130
BindingDB Entry DOI: 10.7270/Q2VD70HW |
More data for this
Ligand-Target Pair | |
Long-chain fatty acid transport protein 1
(Homo sapiens (Human)) | BDBM50387675
(CHEMBL2058080)Show SMILES CCn1c(CNc2ccccc2)nnc1SCC(=O)Nc1ccc(cc1)C(O)=O Show InChI InChI=1S/C20H21N5O3S/c1-2-25-17(12-21-15-6-4-3-5-7-15)23-24-20(25)29-13-18(26)22-16-10-8-14(9-11-16)19(27)28/h3-11,21H,2,12-13H2,1H3,(H,22,26)(H,27,28) | Reactome pathway
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PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant FATP1 acyl-coA synthetase activity using [14C]oleic acid as substrate |
Bioorg Med Chem Lett 22: 5067-70 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.130
BindingDB Entry DOI: 10.7270/Q2VD70HW |
More data for this
Ligand-Target Pair | |
Long-chain fatty acid transport protein 1
(Homo sapiens (Human)) | BDBM50387676
(CHEMBL2058079)Show SMILES CCn1c(CNc2ccccc2)nnc1SCC(=O)Nc1ccc(cc1)C(=O)OC(C)(C)C Show InChI InChI=1S/C24H29N5O3S/c1-5-29-20(15-25-18-9-7-6-8-10-18)27-28-23(29)33-16-21(30)26-19-13-11-17(12-14-19)22(31)32-24(2,3)4/h6-14,25H,5,15-16H2,1-4H3,(H,26,30) | Reactome pathway
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PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant FATP1 acyl-coA synthetase activity using [14C]oleic acid as substrate |
Bioorg Med Chem Lett 22: 5067-70 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.130
BindingDB Entry DOI: 10.7270/Q2VD70HW |
More data for this
Ligand-Target Pair | |
Long-chain fatty acid transport protein 1
(Homo sapiens (Human)) | BDBM50387678
(CHEMBL2058077)Show SMILES CCOC(=O)c1cccc(NC(=O)CSc2nnc(CNc3ccccc3)n2CC)c1 Show InChI InChI=1S/C22H25N5O3S/c1-3-27-19(14-23-17-10-6-5-7-11-17)25-26-22(27)31-15-20(28)24-18-12-8-9-16(13-18)21(29)30-4-2/h5-13,23H,3-4,14-15H2,1-2H3,(H,24,28) | Reactome pathway
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PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant FATP1 acyl-coA synthetase activity using [14C]oleic acid as substrate |
Bioorg Med Chem Lett 22: 5067-70 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.130
BindingDB Entry DOI: 10.7270/Q2VD70HW |
More data for this
Ligand-Target Pair | |
Long-chain fatty acid transport protein 1
(Homo sapiens (Human)) | BDBM50387682
(CHEMBL2058348)Show SMILES CCC(O)c1ccc2oc(CSc3nnc(CNc4ccccc4)n3CC)nc2c1 Show InChI InChI=1S/C22H25N5O2S/c1-3-18(28)15-10-11-19-17(12-15)24-21(29-19)14-30-22-26-25-20(27(22)4-2)13-23-16-8-6-5-7-9-16/h5-12,18,23,28H,3-4,13-14H2,1-2H3 | Reactome pathway
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UniChem
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| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant FATP1 acyl-coA synthetase activity using [14C]oleic acid as substrate |
Bioorg Med Chem Lett 22: 5067-70 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.130
BindingDB Entry DOI: 10.7270/Q2VD70HW |
More data for this
Ligand-Target Pair | |
Long-chain fatty acid transport protein 1
(Mus musculus) | BDBM50387705
(CHEMBL2058091)Show SMILES CCC(=O)c1ccc(NC(=O)CSc2nnc(CNc3ccccc3)n2CC)cc1 Show InChI InChI=1S/C22H25N5O2S/c1-3-19(28)16-10-12-18(13-11-16)24-21(29)15-30-22-26-25-20(27(22)4-2)14-23-17-8-6-5-7-9-17/h5-13,23H,3-4,14-15H2,1-2H3,(H,24,29) | Reactome pathway
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PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of mouse recombinant FATP1 acyl-coA synthetase activity using [14C]oleic acid as substrate |
Bioorg Med Chem Lett 22: 5067-70 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.130
BindingDB Entry DOI: 10.7270/Q2VD70HW |
More data for this
Ligand-Target Pair | |
Long-chain fatty acid transport protein 1
(Homo sapiens (Human)) | BDBM50387685
(CHEMBL2058357)Show InChI InChI=1S/C19H18ClN5OS/c1-2-25-17(11-21-14-6-4-3-5-7-14)23-24-19(25)27-12-18-22-15-9-8-13(20)10-16(15)26-18/h3-10,21H,2,11-12H2,1H3 | Reactome pathway
KEGG
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UniChem
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PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant FATP1 acyl-coA synthetase activity using [14C]oleic acid as substrate |
Bioorg Med Chem Lett 22: 5067-70 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.130
BindingDB Entry DOI: 10.7270/Q2VD70HW |
More data for this
Ligand-Target Pair | |
Long-chain fatty acid transport protein 1
(Homo sapiens (Human)) | BDBM50387686
(CHEMBL2058356)Show InChI InChI=1S/C19H18ClN5OS/c1-2-25-17(11-21-14-6-4-3-5-7-14)23-24-19(25)27-12-18-22-15-10-13(20)8-9-16(15)26-18/h3-10,21H,2,11-12H2,1H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
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PC cid
PC sid
UniChem
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PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant FATP1 acyl-coA synthetase activity using [14C]oleic acid as substrate |
Bioorg Med Chem Lett 22: 5067-70 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.130
BindingDB Entry DOI: 10.7270/Q2VD70HW |
More data for this
Ligand-Target Pair | |
Long-chain fatty acid transport protein 1
(Homo sapiens (Human)) | BDBM50387687
(CHEMBL2058355)Show InChI InChI=1S/C19H18FN5OS/c1-2-25-17(11-21-14-6-4-3-5-7-14)23-24-19(25)27-12-18-22-15-10-13(20)8-9-16(15)26-18/h3-10,21H,2,11-12H2,1H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
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PC cid
PC sid
UniChem
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PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant FATP1 acyl-coA synthetase activity using [14C]oleic acid as substrate |
Bioorg Med Chem Lett 22: 5067-70 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.130
BindingDB Entry DOI: 10.7270/Q2VD70HW |
More data for this
Ligand-Target Pair | |
Long-chain fatty acid transport protein 1
(Homo sapiens (Human)) | BDBM50387688
(CHEMBL2058354)Show InChI InChI=1S/C21H23N5OS/c1-3-15-10-11-18-17(12-15)23-20(27-18)14-28-21-25-24-19(26(21)4-2)13-22-16-8-6-5-7-9-16/h5-12,22H,3-4,13-14H2,1-2H3 | Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant FATP1 acyl-coA synthetase activity using [14C]oleic acid as substrate |
Bioorg Med Chem Lett 22: 5067-70 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.130
BindingDB Entry DOI: 10.7270/Q2VD70HW |
More data for this
Ligand-Target Pair | |
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