| Reaction Details |
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 | Report a problem with these data |
| Target | Peptidyl-prolyl cis-trans isomerase FKBP4 |
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| Ligand | BDBM50388288 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_829706 (CHEMBL2061146) |
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| IC50 | 20300±n/a nM |
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| Citation |  Gopalakrishnan, R; Kozany, C; Wang, Y; Schneider, S; Hoogeland, B; Bracher, A; Hausch, F Exploration of pipecolate sulfonamides as binders of the FK506-binding proteins 51 and 52. J Med Chem55:4123-31 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Peptidyl-prolyl cis-trans isomerase FKBP4 |
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| Name: | Peptidyl-prolyl cis-trans isomerase FKBP4 |
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| Synonyms: | FK506 binding protein 4 | FKBP4 | FKBP4_HUMAN | FKBP52 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 51793.87 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_154482 |
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| Residue: | 459 |
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| Sequence: | MTAEEMKATESGAQSAPLPMEGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGW
LLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPP
KIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKD
KLFDQRELRFEIGEGENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPN
AELKYELHLKSFEKAKESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWL
EYESSFSNEEAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRG
EAHLAVNDFELARADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLYANMFERLAE
EENKAKAEASSGDHPTDTEMKEEQKSNTAGSQSQVETEA
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| BDBM50388288 |
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| n/a |
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| Name | BDBM50388288 |
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| Synonyms: | CHEMBL2058494 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H33Cl2NO10S |
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| Mol. Mass. | 682.565 |
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| SMILES | COc1ccc(CC[C@@H](OC(=O)[C@@H]2CCCCN2S(=O)(=O)c2cc(Cl)c(O)c(Cl)c2)c2cccc(OCC(O)=O)c2)cc1OC |r| |
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| Structure | 
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