| Reaction Details |
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 | Report a problem with these data |
| Target | Peptidyl-prolyl cis-trans isomerase FKBP1A |
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| Ligand | BDBM50388314 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_829709 (CHEMBL2061149) |
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| IC50 | 60±n/a nM |
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| Citation |  Gopalakrishnan, R; Kozany, C; Gaali, S; Kress, C; Hoogeland, B; Bracher, A; Hausch, F Evaluation of synthetic FK506 analogues as ligands for the FK506-binding proteins 51 and 52. J Med Chem55:4114-22 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Peptidyl-prolyl cis-trans isomerase FKBP1A |
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| Name: | Peptidyl-prolyl cis-trans isomerase FKBP1A |
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| Synonyms: | 12 kDa FK506-binding protein | 12 kDa FKBP | FK506-binding protein 1A | FK506-binding protein 1A (FKBP12) | FKB1A_HUMAN | FKBP-12 | FKBP-1A | FKBP1 | FKBP12 | FKBP1A | Immunophilin FKBP12 | PPIase | PPIase FKBP1A | Peptidyl-prolyl cis-trans isomerase (FKBP) | Rotamase | RyR1/FKBP12 | mTOR/FKBP12A/FKBP12B |
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| Type: | Isomerase |
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| Mol. Mass.: | 11953.09 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P62942 |
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| Residue: | 108 |
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| Sequence: | MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGW
EEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE
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| BDBM50388314 |
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| n/a |
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| Name | BDBM50388314 |
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| Synonyms: | CHEMBL2059029 |
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| Type | Small organic molecule |
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| Emp. Form. | C34H43NO10 |
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| Mol. Mass. | 625.7059 |
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| SMILES | COc1ccc(CC[C@@H](OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)CCCC[C@H]2C)c2cccc(OCC(O)=O)c2)cc1OC |r| |
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| Structure | 
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