| Reaction Details |
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 | Report a problem with these data |
| Target | M-phase inducer phosphatase 3 |
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| Ligand | BDBM50388822 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_830917 (CHEMBL2065466) |
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| IC50 | >100000±n/a nM |
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| Citation |  Tsuchiya, A; Hirai, G; Koyama, Y; Oonuma, K; Otani, Y; Osada, H; Sodeoka, M Dual-Specificity Phosphatase CDC25A/B Inhibitor Identified from a Focused Library with Nonelectrophilic Core Structure. ACS Med Chem Lett3:294-298 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| M-phase inducer phosphatase 3 |
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| Name: | M-phase inducer phosphatase 3 |
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| Synonyms: | CDC25C | Dual specificity phosphatase Cdc25C | M-phase inducer phosphatase 3 | MPIP3_HUMAN |
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| Type: | Substrate |
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| Mol. Mass.: | 53366.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30307 |
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| Residue: | 473 |
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| Sequence: | MSTELFSSTREEGSSGSGPSFRSNQRKMLNLLLERDTSFTVCPDVPRTPVGKFLGDSANL
SILSGGTPKRCLDLSNLSSGEITATQLTTSADLDETGHLDSSGLQEVHLAGMNHDQHLMK
CSPAQLLCSTPNGLDRGHRKRDAMCSSSANKENDNGNLVDSEMKYLGSPITTVPKLDKNP
NLGEDQAEEISDELMEFSLKDQEAKVSRSGLYRSPSMPENLNRPRLKQVEKFKDNTIPDK
VKKKYFSGQGKLRKGLCLKKTVSLCDITITQMLEEDSNQGHLIGDFSKVCALPTVSGKHQ
DLKYVNPETVAALLSGKFQGLIEKFYVIDCRYPYEYLGGHIQGALNLYSQEELFNFFLKK
PIVPLDTQKRIIIVFHCEFSSERGPRMCRCLREEDRSLNQYPALYYPELYILKGGYRDFF
PEYMELCEPQSYCPMHHQDHKTELLRCRSQSKVQEGERQLREQIALLVKDMSP
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| BDBM50388822 |
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| n/a |
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| Name | BDBM50388822 |
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| Synonyms: | CHEMBL2062592 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H42ClNO4 |
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| Mol. Mass. | 492.09 |
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| SMILES | CCCCCCCCCCCCCCCC(NCc1cccc(Cl)c1)=C1C(=O)OC(CO)C1=O |w:15.15| |
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| Structure | 
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