| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier family 22 member 7 |
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| Ligand | BDBM82898 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_835936 (CHEMBL2077074) |
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| IC50 | 1410000±n/a nM |
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| Citation |  Khamdang, S; Takeda, M; Babu, E; Noshiro, R; Onozato, ML; Tojo, A; Enomoto, A; Huang, XL; Narikawa, S; Anzai, N; Piyachaturawat, P; Endou, H Interaction of human and rat organic anion transporter 2 with various cephalosporin antibiotics. Eur J Pharmacol465:1-7 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier family 22 member 7 |
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| Name: | Solute carrier family 22 member 7 |
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| Synonyms: | NLT | Novel liver transporter | OAT2 | Organic anion transporter 2 | S22A7_HUMAN | SLC22A7 | hOAT2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 60027.96 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_836101 |
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| Residue: | 548 |
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| Sequence: | MGFEELLEQVGGFGPFQLRNVALLALPRVLLPLHFLLPIFLAAVPAHRCALPGAPANFSH
QDVWLEAHLPREPDGTLSSCLRFAYPQALPNTTLGEERQSRGELEDEPATVPCSQGWEYD
HSEFSSTIATESQWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYV
STLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPLELEWLDVEHRTVAGVLSSTFW
TGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRYLLH
CARLNGRPVCEDSFSQEAVSKVAAGERVVRRPSYLDLFRTPRLRHISLCCVVVWFGVNFS
YYGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALAFGTR
LLVSSDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGGSLA
PLAALLDGVWLSLPKLTYGGIALLAAGTALLLPETRQAQLPETIQDVERKSAPTSLQEEE
MPMKQVQN
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| BDBM82898 |
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| n/a |
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| Name | BDBM82898 |
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| Synonyms: | (6R,7R)-3-(acetoxymethyl)-8-keto-7-[[2-(2-thienyl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid | (6R,7R)-3-(acetyloxymethyl)-8-oxidanylidene-7-(2-thiophen-2-ylethanoylamino)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid | (6R,7R)-3-(acetyloxymethyl)-8-oxo-7-[(1-oxo-2-thiophen-2-ylethyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid | (6R,7R)-3-(acetyloxymethyl)-8-oxo-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid | Cephalothin | MLS001048966 | SMR000386987 | cid_6024 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H16N2O6S2 |
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| Mol. Mass. | 396.438 |
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| SMILES | CC(=O)OCC1=C(N2[C@H](SC1)[C@H](NC(=O)Cc1cccs1)C2=O)C(O)=O |t:5| |
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| Structure | 
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