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Compile Data Set for Download or QSAR

Found 54 hits with Last Name = 'anzai' and Initial = 'n'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Solute carrier family 22 member 16


(Homo sapiens (Human))		BDBM50037268
PNG
((-)-Carnitine | (-)-L-Carnitine | (3R)-3-hydroxy-4...)
Show SMILES C[N+](C)(C)C[C@H](O)CC([O-])=O |r|
Show InChI InChI=1S/C7H15NO3/c1-8(2,3)5-6(9)4-7(10)11/h6,9H,4-5H2,1-3H3/t6-/m1/s1
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 3.00E+4n/an/an/an/an/an/an/an/a



Kyorin University

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of carnitine in Xenopus laevis oocytes

J Biol Chem 277: 36262-71 (2002)


Article DOI: 10.1074/jbc.M203883200
BindingDB Entry DOI: 10.7270/Q20003CS
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM318948
PNG
(2-Methyl-2-[[7-(4-nitrophenyl)benzo[d]isothiazol-6...)
Show SMILES CC(C)(Sc1ccc2cnsc2c1-c1ccc(cc1)[N+]([O-])=O)C(O)=O
Show InChI InChI=1S/C17H14N2O4S2/c1-17(2,16(20)21)24-13-8-5-11-9-18-25-15(11)14(13)10-3-6-12(7-4-10)19(22)23/h3-9H,1-2H3,(H,20,21)
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n/an/a 12n/an/an/an/an/an/a



Nippon Chemiphar Co., Ltd.; J-Pharma Co., Ltd.; DeThree Res. Lab. Inc.

US Patent


Assay Description
URAT1 stably expressed HEK293 cells (HEK-URAT1) or HEK293 cells transfected with empty vector (HEK-mock) were cultured in DMEM culture medium supplem...

US Patent US10173990 (2019)


BindingDB Entry DOI: 10.7270/Q2RR21BP
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM318954
PNG
(2-[[7-(4-Cyanophenyl)benzo[d]isothiazol-6-yl]thio]...)
Show SMILES CCC(CC)(Sc1ccc2cnsc2c1-c1ccc(cc1)C#N)C(O)=O
Show InChI InChI=1S/C20H18N2O2S2/c1-3-20(4-2,19(23)24)25-16-10-9-15-12-22-26-18(15)17(16)14-7-5-13(11-21)6-8-14/h5-10,12H,3-4H2,1-2H3,(H,23,24)
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n/an/a 21n/an/an/an/an/an/a



Nippon Chemiphar Co., Ltd.; J-Pharma Co., Ltd.; DeThree Res. Lab. Inc.

US Patent


Assay Description
URAT1 stably expressed HEK293 cells (HEK-URAT1) or HEK293 cells transfected with empty vector (HEK-mock) were cultured in DMEM culture medium supplem...

US Patent US10173990 (2019)


BindingDB Entry DOI: 10.7270/Q2RR21BP
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM318946
PNG
(1-[[7-(4-Cyanophenyl)benzo[d]isothiazol-6-yl]thio]...)
Show SMILES OC(=O)C1(CCC1)Sc1ccc2cnsc2c1-c1ccc(cc1)C#N
Show InChI InChI=1S/C19H14N2O2S2/c20-10-12-2-4-13(5-3-12)16-15(7-6-14-11-21-25-17(14)16)24-19(18(22)23)8-1-9-19/h2-7,11H,1,8-9H2,(H,22,23)
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n/an/a 21.5n/an/an/an/an/an/a



Nippon Chemiphar Co., Ltd.; J-Pharma Co., Ltd.; DeThree Res. Lab. Inc.

US Patent


Assay Description
URAT1 stably expressed HEK293 cells (HEK-URAT1) or HEK293 cells transfected with empty vector (HEK-mock) were cultured in DMEM culture medium supplem...

US Patent US10173990 (2019)


BindingDB Entry DOI: 10.7270/Q2RR21BP
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM318956
PNG
((E)-3-[[1-(4-cyanophenyl)naphthalen-2-yl]thio]-2-b...)
Show SMILES C\C(Sc1ccc2ccccc2c1-c1ccc(cc1)C#N)=C/C(O)=O
Show InChI InChI=1S/C21H15NO2S/c1-14(12-20(23)24)25-19-11-10-16-4-2-3-5-18(16)21(19)17-8-6-15(13-22)7-9-17/h2-12H,1H3,(H,23,24)/b14-12+
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n/an/a 25n/an/an/an/an/an/a



Nippon Chemiphar Co., Ltd.; J-Pharma Co., Ltd.; DeThree Res. Lab. Inc.

US Patent


Assay Description
URAT1 stably expressed HEK293 cells (HEK-URAT1) or HEK293 cells transfected with empty vector (HEK-mock) were cultured in DMEM culture medium supplem...

US Patent US10173990 (2019)


BindingDB Entry DOI: 10.7270/Q2RR21BP
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM50158460
PNG
((3,5-dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran...)
Show SMILES CCc1oc2ccccc2c1C(=O)c1cc(Br)c(O)c(Br)c1
Show InChI InChI=1S/C17H12Br2O3/c1-2-13-15(10-5-3-4-6-14(10)22-13)16(20)9-7-11(18)17(21)12(19)8-9/h3-8,21H,2H2,1H3
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n/an/a 26n/an/an/an/an/an/a



University of Colorado Anschutz Medical Campus

Curated by ChEMBL


Assay Description
Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou...

J Med Chem 54: 2701-13 (2011)


Article DOI: 10.1021/jm1015022
BindingDB Entry DOI: 10.7270/Q2P26ZDR
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM318947
PNG
(1-[[7-(4-Cyanophenyl)benzo[d]isothiazol-6-yl]thio]...)
Show SMILES OC(=O)C1(CCCC1)Sc1ccc2cnsc2c1-c1ccc(cc1)C#N
Show InChI InChI=1S/C20H16N2O2S2/c21-11-13-3-5-14(6-4-13)17-16(8-7-15-12-22-26-18(15)17)25-20(19(23)24)9-1-2-10-20/h3-8,12H,1-2,9-10H2,(H,23,24)
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n/an/a 26.2n/an/an/an/an/an/a



Nippon Chemiphar Co., Ltd.; J-Pharma Co., Ltd.; DeThree Res. Lab. Inc.

US Patent


Assay Description
URAT1 stably expressed HEK293 cells (HEK-URAT1) or HEK293 cells transfected with empty vector (HEK-mock) were cultured in DMEM culture medium supplem...

US Patent US10173990 (2019)


BindingDB Entry DOI: 10.7270/Q2RR21BP
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM50158460
PNG
((3,5-dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran...)
Show SMILES CCc1oc2ccccc2c1C(=O)c1cc(Br)c(O)c(Br)c1
Show InChI InChI=1S/C17H12Br2O3/c1-2-13-15(10-5-3-4-6-14(10)22-13)16(20)9-7-11(18)17(21)12(19)8-9/h3-8,21H,2H2,1H3
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n/an/a 35n/an/an/an/an/an/a



University of Colorado Anschutz Medical Campus

Curated by ChEMBL


Assay Description
Inhibition of human URAT1 expressed in human MDCK cells

J Med Chem 54: 2701-13 (2011)


Article DOI: 10.1021/jm1015022
BindingDB Entry DOI: 10.7270/Q2P26ZDR
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM50342286
PNG
((3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-5-methoxyben...)
Show SMILES CCc1oc2ccc(OC)cc2c1C(=O)c1cc(Br)c(O)c(Br)c1
Show InChI InChI=1S/C18H14Br2O4/c1-3-14-16(11-8-10(23-2)4-5-15(11)24-14)17(21)9-6-12(19)18(22)13(20)7-9/h4-8,22H,3H2,1-2H3
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n/an/a 42n/an/an/an/an/an/a



University of Colorado Anschutz Medical Campus

Curated by ChEMBL


Assay Description
Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou...

J Med Chem 54: 2701-13 (2011)


Article DOI: 10.1021/jm1015022
BindingDB Entry DOI: 10.7270/Q2P26ZDR
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM50342289
PNG
((3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-5-hydroxyben...)
Show SMILES CCc1cc2c(C(=O)c3cc(Br)c(O)c(Br)c3)c(O)ccc2o1
Show InChI InChI=1S/C17H12Br2O4/c1-2-9-7-10-14(23-9)4-3-13(20)15(10)16(21)8-5-11(18)17(22)12(19)6-8/h3-7,20,22H,2H2,1H3
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n/an/a 83n/an/an/an/an/an/a



University of Colorado Anschutz Medical Campus

Curated by ChEMBL


Assay Description
Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou...

J Med Chem 54: 2701-13 (2011)


Article DOI: 10.1021/jm1015022
BindingDB Entry DOI: 10.7270/Q2P26ZDR
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM318949
PNG
(2-Methyl-2-[[7-[4-(trifluoromethyl)phenyl]benzo[d]...)
Show SMILES CC(C)(Sc1ccc2cnsc2c1-c1ccc(cc1)C(F)(F)F)C(O)=O
Show InChI InChI=1S/C18H14F3NO2S2/c1-17(2,16(23)24)25-13-8-5-11-9-22-26-15(11)14(13)10-3-6-12(7-4-10)18(19,20)21/h3-9H,1-2H3,(H,23,24)
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n/an/a 104n/an/an/an/an/an/a



Nippon Chemiphar Co., Ltd.; J-Pharma Co., Ltd.; DeThree Res. Lab. Inc.

US Patent


Assay Description
URAT1 stably expressed HEK293 cells (HEK-URAT1) or HEK293 cells transfected with empty vector (HEK-mock) were cultured in DMEM culture medium supplem...

US Patent US10173990 (2019)


BindingDB Entry DOI: 10.7270/Q2RR21BP
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM318950
PNG
(2-[[7-(4-Chlorophenyl)benzo[d]isothiazol-6-yl]thio...)
Show SMILES CC(C)(Sc1ccc2cnsc2c1-c1ccc(Cl)cc1)C(O)=O
Show InChI InChI=1S/C17H14ClNO2S2/c1-17(2,16(20)21)22-13-8-5-11-9-19-23-15(11)14(13)10-3-6-12(18)7-4-10/h3-9H,1-2H3,(H,20,21)
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n/an/a 106n/an/an/an/an/an/a



Nippon Chemiphar Co., Ltd.; J-Pharma Co., Ltd.; DeThree Res. Lab. Inc.

US Patent


Assay Description
URAT1 stably expressed HEK293 cells (HEK-URAT1) or HEK293 cells transfected with empty vector (HEK-mock) were cultured in DMEM culture medium supplem...

US Patent US10173990 (2019)


BindingDB Entry DOI: 10.7270/Q2RR21BP
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM50342292
PNG
((3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-6-methoxyben...)
Show SMILES CCc1oc2cc(OC)ccc2c1C(=O)c1cc(Br)c(O)c(Br)c1
Show InChI InChI=1S/C18H14Br2O4/c1-3-14-16(11-5-4-10(23-2)8-15(11)24-14)17(21)9-6-12(19)18(22)13(20)7-9/h4-8,22H,3H2,1-2H3
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n/an/a 111n/an/an/an/an/an/a



University of Colorado Anschutz Medical Campus

Curated by ChEMBL


Assay Description
Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou...

J Med Chem 54: 2701-13 (2011)


Article DOI: 10.1021/jm1015022
BindingDB Entry DOI: 10.7270/Q2P26ZDR
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM50342279
PNG
((3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-6-hydroxy-be...)
Show SMILES CCc1oc2cc(O)ccc2c1C(=O)c1cc(Br)c(O)c(Br)c1
Show InChI InChI=1S/C17H12Br2O4/c1-2-13-15(10-4-3-9(20)7-14(10)23-13)16(21)8-5-11(18)17(22)12(19)6-8/h3-7,20,22H,2H2,1H3
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n/an/a 138n/an/an/an/an/an/a



University of Colorado Anschutz Medical Campus

Curated by ChEMBL


Assay Description
Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou...

J Med Chem 54: 2701-13 (2011)


Article DOI: 10.1021/jm1015022
BindingDB Entry DOI: 10.7270/Q2P26ZDR
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM318952
PNG
(2-[[7-(4-Cyano-3-fluorophenyl)benzo[d]isothiazol-6...)
Show SMILES CC(C)(Sc1ccc2cnsc2c1-c1ccc(C#N)c(F)c1)C(O)=O
Show InChI InChI=1S/C18H13FN2O2S2/c1-18(2,17(22)23)24-14-6-5-12-9-21-25-16(12)15(14)10-3-4-11(8-20)13(19)7-10/h3-7,9H,1-2H3,(H,22,23)
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n/an/a 161n/an/an/an/an/an/a



Nippon Chemiphar Co., Ltd.; J-Pharma Co., Ltd.; DeThree Res. Lab. Inc.

US Patent


Assay Description
URAT1 stably expressed HEK293 cells (HEK-URAT1) or HEK293 cells transfected with empty vector (HEK-mock) were cultured in DMEM culture medium supplem...

US Patent US10173990 (2019)


BindingDB Entry DOI: 10.7270/Q2RR21BP
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM318944
PNG
(2-[[7-(4-Cyanophenyl)benzo[d]thiazol-6-yl]thio]-2-...)
Show SMILES CC(C)(Sc1ccc2ncsc2c1-c1ccc(cc1)C#N)C(O)=O
Show InChI InChI=1S/C18H14N2O2S2/c1-18(2,17(21)22)24-14-8-7-13-16(23-10-20-13)15(14)12-5-3-11(9-19)4-6-12/h3-8,10H,1-2H3,(H,21,22)
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n/an/a 170n/an/an/an/an/an/a



Nippon Chemiphar Co., Ltd.; J-Pharma Co., Ltd.; DeThree Res. Lab. Inc.

US Patent


Assay Description
URAT1 stably expressed HEK293 cells (HEK-URAT1) or HEK293 cells transfected with empty vector (HEK-mock) were cultured in DMEM culture medium supplem...

US Patent US10173990 (2019)


BindingDB Entry DOI: 10.7270/Q2RR21BP
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM50342294
PNG
((6-Bromo-2-ethyl-7-hydroxybenzofuran-4-yl)(3,5-dib...)
Show SMILES CCc1cc2c(cc(Br)c(O)c2o1)C(=O)c1cc(Br)c(O)c(Br)c1
Show InChI InChI=1S/C17H11Br3O4/c1-2-8-5-10-9(6-13(20)16(23)17(10)24-8)14(21)7-3-11(18)15(22)12(19)4-7/h3-6,22-23H,2H2,1H3
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n/an/a 177n/an/an/an/an/an/a



University of Colorado Anschutz Medical Campus

Curated by ChEMBL


Assay Description
Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou...

J Med Chem 54: 2701-13 (2011)


Article DOI: 10.1021/jm1015022
BindingDB Entry DOI: 10.7270/Q2P26ZDR
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM50342287
PNG
((3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-5-hydroxyben...)
Show SMILES CCc1oc2ccc(O)cc2c1C(=O)c1cc(Br)c(O)c(Br)c1
Show InChI InChI=1S/C17H12Br2O4/c1-2-13-15(10-7-9(20)3-4-14(10)23-13)16(21)8-5-11(18)17(22)12(19)6-8/h3-7,20,22H,2H2,1H3
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n/an/a 189n/an/an/an/an/an/a



University of Colorado Anschutz Medical Campus

Curated by ChEMBL


Assay Description
Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou...

J Med Chem 54: 2701-13 (2011)


Article DOI: 10.1021/jm1015022
BindingDB Entry DOI: 10.7270/Q2P26ZDR
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM50342279
PNG
((3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-6-hydroxy-be...)
Show SMILES CCc1oc2cc(O)ccc2c1C(=O)c1cc(Br)c(O)c(Br)c1
Show InChI InChI=1S/C17H12Br2O4/c1-2-13-15(10-4-3-9(20)7-14(10)23-13)16(21)8-5-11(18)17(22)12(19)6-8/h3-7,20,22H,2H2,1H3
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n/an/a 200n/an/an/an/an/an/a



University of Colorado Anschutz Medical Campus

Curated by ChEMBL


Assay Description
Inhibition of human URAT1 expressed in human MDCK cells

J Med Chem 54: 2701-13 (2011)


Article DOI: 10.1021/jm1015022
BindingDB Entry DOI: 10.7270/Q2P26ZDR
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM318951
PNG
(2-[[7-(3-Cyanophenyl)benzo[d]isothiazol-6-yl]thio]...)
Show SMILES CC(C)(Sc1ccc2cnsc2c1-c1cccc(c1)C#N)C(O)=O
Show InChI InChI=1S/C18H14N2O2S2/c1-18(2,17(21)22)23-14-7-6-13-10-20-24-16(13)15(14)12-5-3-4-11(8-12)9-19/h3-8,10H,1-2H3,(H,21,22)
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n/an/a 205n/an/an/an/an/an/a



Nippon Chemiphar Co., Ltd.; J-Pharma Co., Ltd.; DeThree Res. Lab. Inc.

US Patent


Assay Description
URAT1 stably expressed HEK293 cells (HEK-URAT1) or HEK293 cells transfected with empty vector (HEK-mock) were cultured in DMEM culture medium supplem...

US Patent US10173990 (2019)


BindingDB Entry DOI: 10.7270/Q2RR21BP
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM50342291
PNG
((3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-5-hydroxyben...)
Show SMILES CCc1cc2cc(O)cc(C(=O)c3cc(Br)c(O)c(Br)c3)c2o1
Show InChI InChI=1S/C17H12Br2O4/c1-2-11-4-9-3-10(20)7-12(17(9)23-11)15(21)8-5-13(18)16(22)14(19)6-8/h3-7,20,22H,2H2,1H3
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n/an/a 287n/an/an/an/an/an/a



University of Colorado Anschutz Medical Campus

Curated by ChEMBL


Assay Description
Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou...

J Med Chem 54: 2701-13 (2011)


Article DOI: 10.1021/jm1015022
BindingDB Entry DOI: 10.7270/Q2P26ZDR
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM318957
PNG
(1-[[7-(4-Cyanophenyl)benzo[d]isothazol-6-yl]thio]c...)
Show SMILES OC(=O)C1(CCCCC1)Sc1ccc2cnsc2c1-c1ccc(cc1)C#N
Show InChI InChI=1S/C21H18N2O2S2/c22-12-14-4-6-15(7-5-14)18-17(9-8-16-13-23-27-19(16)18)26-21(20(24)25)10-2-1-3-11-21/h4-9,13H,1-3,10-11H2,(H,24,25)
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n/an/a 296n/an/an/an/an/an/a



Nippon Chemiphar Co., Ltd.; J-Pharma Co., Ltd.; DeThree Res. Lab. Inc.

US Patent


Assay Description
URAT1 stably expressed HEK293 cells (HEK-URAT1) or HEK293 cells transfected with empty vector (HEK-mock) were cultured in DMEM culture medium supplem...

US Patent US10173990 (2019)


BindingDB Entry DOI: 10.7270/Q2RR21BP
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM50342288
PNG
((3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-5-methoxyben...)
Show SMILES CCc1cc2c(C(=O)c3cc(Br)c(O)c(Br)c3)c(OC)ccc2o1
Show InChI InChI=1S/C18H14Br2O4/c1-3-10-8-11-14(24-10)4-5-15(23-2)16(11)17(21)9-6-12(19)18(22)13(20)7-9/h4-8,22H,3H2,1-2H3
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n/an/a 358n/an/an/an/an/an/a



University of Colorado Anschutz Medical Campus

Curated by ChEMBL


Assay Description
Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou...

J Med Chem 54: 2701-13 (2011)


Article DOI: 10.1021/jm1015022
BindingDB Entry DOI: 10.7270/Q2P26ZDR
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM318955
PNG
(2-[[7-(4-Cyanophenyl)benzo[d]isothiazol-6-yl]thio]...)
Show SMILES CC(C)(C)C(Sc1ccc2cnsc2c1-c1ccc(cc1)C#N)C(O)=O
Show InChI InChI=1S/C20H18N2O2S2/c1-20(2,3)18(19(23)24)25-15-9-8-14-11-22-26-17(14)16(15)13-6-4-12(10-21)5-7-13/h4-9,11,18H,1-3H3,(H,23,24)
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n/an/a 474n/an/an/an/an/an/a



Nippon Chemiphar Co., Ltd.; J-Pharma Co., Ltd.; DeThree Res. Lab. Inc.

US Patent


Assay Description
URAT1 stably expressed HEK293 cells (HEK-URAT1) or HEK293 cells transfected with empty vector (HEK-mock) were cultured in DMEM culture medium supplem...

US Patent US10173990 (2019)


BindingDB Entry DOI: 10.7270/Q2RR21BP
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM50342296
PNG
((5,7-Dibromo-2-ethyl-6-hydroxybenzofuran-3-yl)(4-m...)
Show SMILES CCc1oc2c(Br)c(O)c(Br)cc2c1C(=O)c1ccc(OC)cc1
Show InChI InChI=1S/C18H14Br2O4/c1-3-13-14(16(21)9-4-6-10(23-2)7-5-9)11-8-12(19)17(22)15(20)18(11)24-13/h4-8,22H,3H2,1-2H3
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n/an/a 667n/an/an/an/an/an/a



University of Colorado Anschutz Medical Campus

Curated by ChEMBL


Assay Description
Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou...

J Med Chem 54: 2701-13 (2011)


Article DOI: 10.1021/jm1015022
BindingDB Entry DOI: 10.7270/Q2P26ZDR
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM50342297
PNG
((6-Bromo-2-ethyl-7-hydroxybenzofuran-4-yl)(4-metho...)
Show SMILES CCc1cc2c(cc(Br)c(O)c2o1)C(=O)c1ccc(OC)cc1
Show InChI InChI=1S/C18H15BrO4/c1-3-11-8-14-13(9-15(19)17(21)18(14)23-11)16(20)10-4-6-12(22-2)7-5-10/h4-9,21H,3H2,1-2H3
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n/an/a 772n/an/an/an/an/an/a



University of Colorado Anschutz Medical Campus

Curated by ChEMBL


Assay Description
Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou...

J Med Chem 54: 2701-13 (2011)


Article DOI: 10.1021/jm1015022
BindingDB Entry DOI: 10.7270/Q2P26ZDR
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM318942
PNG
(2-[(4′-Cyano[1,1′-binaphthalene]-2-yl)...)
Show SMILES CC(C)(Sc1ccc2ccccc2c1-c1ccc(C#N)c2ccccc12)C(O)=O |(-3.75,-2.29,;-4.52,-.95,;-5.29,.38,;-3.19,-.18,;-1.85,-.95,;-1.85,-2.49,;-.52,-3.26,;.81,-2.49,;2.15,-3.26,;3.48,-2.49,;3.48,-.95,;2.15,-.18,;.81,-.95,;-.52,-.18,;-.52,1.36,;-1.85,2.13,;-1.85,3.67,;-.52,4.44,;-.52,5.98,;-.52,7.52,;.81,3.67,;2.15,4.44,;3.48,3.67,;3.48,2.13,;2.15,1.36,;.81,2.13,;-5.85,-1.72,;-5.85,-3.26,;-7.19,-.95,)|
Show InChI InChI=1S/C25H19NO2S/c1-25(2,24(27)28)29-22-14-12-16-7-3-4-9-19(16)23(22)21-13-11-17(15-26)18-8-5-6-10-20(18)21/h3-14H,1-2H3,(H,27,28)
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n/an/a 790n/an/an/an/an/an/a



Nippon Chemiphar Co., Ltd.; J-Pharma Co., Ltd.; DeThree Res. Lab. Inc.

US Patent


Assay Description
URAT1 stably expressed HEK293 cells (HEK-URAT1) or HEK293 cells transfected with empty vector (HEK-mock) were cultured in DMEM culture medium supplem...

US Patent US10173990 (2019)


BindingDB Entry DOI: 10.7270/Q2RR21BP
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM50342283
PNG
((2-Ethyl-6-hydroxybenzofuran-3-yl)(4-hydroxyphenyl...)
Show SMILES CCc1oc2cc(O)ccc2c1C(=O)c1ccc(O)cc1
Show InChI InChI=1S/C17H14O4/c1-2-14-16(13-8-7-12(19)9-15(13)21-14)17(20)10-3-5-11(18)6-4-10/h3-9,18-19H,2H2,1H3
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n/an/a 1.13E+3n/an/an/an/an/an/a



University of Colorado Anschutz Medical Campus

Curated by ChEMBL


Assay Description
Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou...

J Med Chem 54: 2701-13 (2011)


Article DOI: 10.1021/jm1015022
BindingDB Entry DOI: 10.7270/Q2P26ZDR
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM50342290
PNG
((3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-5-methoxyben...)
Show SMILES CCc1cc2cc(OC)cc(C(=O)c3cc(Br)c(O)c(Br)c3)c2o1
Show InChI InChI=1S/C18H14Br2O4/c1-3-11-4-10-5-12(23-2)8-13(18(10)24-11)16(21)9-6-14(19)17(22)15(20)7-9/h4-8,22H,3H2,1-2H3
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n/an/a 1.44E+3n/an/an/an/an/an/a



University of Colorado Anschutz Medical Campus

Curated by ChEMBL


Assay Description
Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou...

J Med Chem 54: 2701-13 (2011)


Article DOI: 10.1021/jm1015022
BindingDB Entry DOI: 10.7270/Q2P26ZDR
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM318945
PNG
(2-[[3-(4-Cyanophenyl)quinolin-4-yl]thio]-2-methylp...)
Show SMILES CC(C)(Sc1c(cnc2ccccc12)-c1ccc(cc1)C#N)C(O)=O
Show InChI InChI=1S/C20H16N2O2S/c1-20(2,19(23)24)25-18-15-5-3-4-6-17(15)22-12-16(18)14-9-7-13(11-21)8-10-14/h3-10,12H,1-2H3,(H,23,24)
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n/an/a 1.58E+3n/an/an/an/an/an/a



Nippon Chemiphar Co., Ltd.; J-Pharma Co., Ltd.; DeThree Res. Lab. Inc.

US Patent


Assay Description
URAT1 stably expressed HEK293 cells (HEK-URAT1) or HEK293 cells transfected with empty vector (HEK-mock) were cultured in DMEM culture medium supplem...

US Patent US10173990 (2019)


BindingDB Entry DOI: 10.7270/Q2RR21BP
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM50342293
PNG
((5-Bromo-2-ethyl-6-methoxybenzofuran-3-yl)(3,5-dib...)
Show SMILES CCc1oc2cc(O)c(Br)cc2c1C(=O)c1cc(Br)c(O)c(Br)c1
Show InChI InChI=1S/C17H11Br3O4/c1-2-13-15(8-5-9(18)12(21)6-14(8)24-13)16(22)7-3-10(19)17(23)11(20)4-7/h3-6,21,23H,2H2,1H3
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n/an/a 1.65E+3n/an/an/an/an/an/a



University of Colorado Anschutz Medical Campus

Curated by ChEMBL


Assay Description
Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou...

J Med Chem 54: 2701-13 (2011)


Article DOI: 10.1021/jm1015022
BindingDB Entry DOI: 10.7270/Q2P26ZDR
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM318941
PNG
(2-[(4′-Cyano-(1,1′-binaphthalene)-2-yl...)
Show SMILES CC(C)(Oc1ccc2ccccc2c1-c1ccc(C#N)c2ccccc12)C(O)=O |(-3.75,-2.29,;-4.52,-.95,;-5.29,.38,;-3.19,-.18,;-1.85,-.95,;-1.85,-2.49,;-.52,-3.26,;.81,-2.49,;2.15,-3.26,;3.48,-2.49,;3.48,-.95,;2.15,-.18,;.81,-.95,;-.52,-.18,;-.52,1.36,;-1.85,2.13,;-1.85,3.67,;-.52,4.44,;-.52,5.98,;-.52,7.52,;.81,3.67,;2.15,4.44,;3.48,3.67,;3.48,2.13,;2.15,1.36,;.81,2.13,;-5.85,-1.72,;-5.85,-3.26,;-7.19,-.95,)|
Show InChI InChI=1S/C25H19NO3/c1-25(2,24(27)28)29-22-14-12-16-7-3-4-9-19(16)23(22)21-13-11-17(15-26)18-8-5-6-10-20(18)21/h3-14H,1-2H3,(H,27,28)
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n/an/a 2.06E+3n/an/an/an/an/an/a



Nippon Chemiphar Co., Ltd.; J-Pharma Co., Ltd.; DeThree Res. Lab. Inc.

US Patent


Assay Description
URAT1 stably expressed HEK293 cells (HEK-URAT1) or HEK293 cells transfected with empty vector (HEK-mock) were cultured in DMEM culture medium supplem...

US Patent US10173990 (2019)


BindingDB Entry DOI: 10.7270/Q2RR21BP
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM318953
PNG
(1-[[7-(4-Cyanophenyl)-3-methylbenzo[d]isothiazol-6...)
Show SMILES Cc1nsc2c(c(SC3(CCC3)C(O)=O)ccc12)-c1ccc(cc1)C#N
Show InChI InChI=1S/C20H16N2O2S2/c1-12-15-7-8-16(25-20(19(23)24)9-2-10-20)17(18(15)26-22-12)14-5-3-13(11-21)4-6-14/h3-8H,2,9-10H2,1H3,(H,23,24)
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n/an/a 2.43E+3n/an/an/an/an/an/a



Nippon Chemiphar Co., Ltd.; J-Pharma Co., Ltd.; DeThree Res. Lab. Inc.

US Patent


Assay Description
URAT1 stably expressed HEK293 cells (HEK-URAT1) or HEK293 cells transfected with empty vector (HEK-mock) were cultured in DMEM culture medium supplem...

US Patent US10173990 (2019)


BindingDB Entry DOI: 10.7270/Q2RR21BP
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM50342277
PNG
((2-Ethyl-5-methoxybenzofuran-3-yl)(4-hydroxyphenyl...)
Show SMILES CCc1oc2ccc(OC)cc2c1C(=O)c1ccc(O)cc1
Show InChI InChI=1S/C18H16O4/c1-3-15-17(18(20)11-4-6-12(19)7-5-11)14-10-13(21-2)8-9-16(14)22-15/h4-10,19H,3H2,1-2H3
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n/an/a 2.46E+3n/an/an/an/an/an/a



University of Colorado Anschutz Medical Campus

Curated by ChEMBL


Assay Description
Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou...

J Med Chem 54: 2701-13 (2011)


Article DOI: 10.1021/jm1015022
BindingDB Entry DOI: 10.7270/Q2P26ZDR
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM50342276
PNG
((2-Ethyl-5-hydroxybenzofuran-3-yl)(4-hydroxyphenyl...)
Show SMILES CCc1oc2ccc(O)cc2c1C(=O)c1ccc(O)cc1
Show InChI InChI=1S/C17H14O4/c1-2-14-16(13-9-12(19)7-8-15(13)21-14)17(20)10-3-5-11(18)6-4-10/h3-9,18-19H,2H2,1H3
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n/an/a 2.49E+3n/an/an/an/an/an/a



University of Colorado Anschutz Medical Campus

Curated by ChEMBL


Assay Description
Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou...

J Med Chem 54: 2701-13 (2011)


Article DOI: 10.1021/jm1015022
BindingDB Entry DOI: 10.7270/Q2P26ZDR
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM50342278
PNG
((2-Ethylbenzofuran-3-yl)(4-hydroxyphenyl)methanone...)
Show SMILES CCc1oc2ccccc2c1C(=O)c1ccc(O)cc1
Show InChI InChI=1S/C17H14O3/c1-2-14-16(13-5-3-4-6-15(13)20-14)17(19)11-7-9-12(18)10-8-11/h3-10,18H,2H2,1H3
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n/an/a 2.80E+3n/an/an/an/an/an/a



University of Colorado Anschutz Medical Campus

Curated by ChEMBL


Assay Description
Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou...

J Med Chem 54: 2701-13 (2011)


Article DOI: 10.1021/jm1015022
BindingDB Entry DOI: 10.7270/Q2P26ZDR
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM318943
PNG
(2-[[5-(4-Cyanophenyl)quinolin-6-yl]thio]-2-methylp...)
Show SMILES CC(C)(Sc1ccc2ncccc2c1-c1ccc(cc1)[N+]#[C-])C(O)=O
Show InChI InChI=1S/C20H16N2O2S/c1-20(2,19(23)24)25-17-11-10-16-15(5-4-12-22-16)18(17)13-6-8-14(21-3)9-7-13/h4-12H,1-2H3,(H,23,24)
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n/an/a 3.44E+3n/an/an/an/an/an/a



Nippon Chemiphar Co., Ltd.; J-Pharma Co., Ltd.; DeThree Res. Lab. Inc.

US Patent


Assay Description
URAT1 stably expressed HEK293 cells (HEK-URAT1) or HEK293 cells transfected with empty vector (HEK-mock) were cultured in DMEM culture medium supplem...

US Patent US10173990 (2019)


BindingDB Entry DOI: 10.7270/Q2RR21BP
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM50342282
PNG
((2-Ethyl-6-methoxybenzofuran-3-yl)(4-hydroxyphenyl...)
Show SMILES CCc1oc2cc(OC)ccc2c1C(=O)c1ccc(O)cc1
Show InChI InChI=1S/C18H16O4/c1-3-15-17(18(20)11-4-6-12(19)7-5-11)14-9-8-13(21-2)10-16(14)22-15/h4-10,19H,3H2,1-2H3
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n/an/a 3.92E+3n/an/an/an/an/an/a



University of Colorado Anschutz Medical Campus

Curated by ChEMBL


Assay Description
Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou...

J Med Chem 54: 2701-13 (2011)


Article DOI: 10.1021/jm1015022
BindingDB Entry DOI: 10.7270/Q2P26ZDR
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM50342285
PNG
((2-Ethyl-7-hydroxybenzofuran-4-yl)(4-hydroxyphenyl...)
Show SMILES CCc1cc2c(ccc(O)c2o1)C(=O)c1ccc(O)cc1
Show InChI InChI=1S/C17H14O4/c1-2-12-9-14-13(7-8-15(19)17(14)21-12)16(20)10-3-5-11(18)6-4-10/h3-9,18-19H,2H2,1H3
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n/an/a 3.94E+3n/an/an/an/an/an/a



University of Colorado Anschutz Medical Campus

Curated by ChEMBL


Assay Description
Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou...

J Med Chem 54: 2701-13 (2011)


Article DOI: 10.1021/jm1015022
BindingDB Entry DOI: 10.7270/Q2P26ZDR
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM50342280
PNG
((2-Ethyl-5-methoxybenzofuran-4-yl)(4-hydroxyphenyl...)
Show SMILES CCc1cc2c(C(=O)c3ccc(O)cc3)c(OC)ccc2o1
Show InChI InChI=1S/C18H16O4/c1-3-13-10-14-15(22-13)8-9-16(21-2)17(14)18(20)11-4-6-12(19)7-5-11/h4-10,19H,3H2,1-2H3
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n/an/a 6.68E+3n/an/an/an/an/an/a



University of Colorado Anschutz Medical Campus

Curated by ChEMBL


Assay Description
Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou...

J Med Chem 54: 2701-13 (2011)


Article DOI: 10.1021/jm1015022
BindingDB Entry DOI: 10.7270/Q2P26ZDR
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM50342284
PNG
((2-Ethyl-6-methoxybenzofuran-4-yl)(4-hydroxyphenyl...)
Show SMILES CCc1cc2c(cc(OC)cc2o1)C(=O)c1ccc(O)cc1
Show InChI InChI=1S/C18H16O4/c1-3-13-8-15-16(9-14(21-2)10-17(15)22-13)18(20)11-4-6-12(19)7-5-11/h4-10,19H,3H2,1-2H3
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n/an/a 1.97E+4n/an/an/an/an/an/a



University of Colorado Anschutz Medical Campus

Curated by ChEMBL


Assay Description
Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou...

J Med Chem 54: 2701-13 (2011)


Article DOI: 10.1021/jm1015022
BindingDB Entry DOI: 10.7270/Q2P26ZDR
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM50342295
PNG
((4,6-Dibromo-2-ethyl-5-hydroxybenzofuran-3-yl)(4-m...)
Show SMILES CCc1oc2cc(Br)c(O)c(Br)c2c1C(=O)c1ccc(OC)cc1
Show InChI InChI=1S/C18H14Br2O4/c1-3-12-15(17(21)9-4-6-10(23-2)7-5-9)14-13(24-12)8-11(19)18(22)16(14)20/h4-8,22H,3H2,1-2H3
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n/an/a 2.35E+4n/an/an/an/an/an/a



University of Colorado Anschutz Medical Campus

Curated by ChEMBL


Assay Description
Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou...

J Med Chem 54: 2701-13 (2011)


Article DOI: 10.1021/jm1015022
BindingDB Entry DOI: 10.7270/Q2P26ZDR
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM50342281
PNG
((2-Ethyl-5-methoxybenzofuran-7-yl)(4-hydroxyphenyl...)
Show SMILES CCc1cc2cc(OC)cc(C(=O)c3ccc(O)cc3)c2o1
Show InChI InChI=1S/C18H16O4/c1-3-14-8-12-9-15(21-2)10-16(18(12)22-14)17(20)11-4-6-13(19)7-5-11/h4-10,19H,3H2,1-2H3
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n/an/a 3.37E+4n/an/an/an/an/an/a



University of Colorado Anschutz Medical Campus

Curated by ChEMBL


Assay Description
Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou...

J Med Chem 54: 2701-13 (2011)


Article DOI: 10.1021/jm1015022
BindingDB Entry DOI: 10.7270/Q2P26ZDR
More data for this
Ligand-Target Pair
Solute carrier family 22 member 12


(Homo sapiens (Human))		BDBM50206509
PNG
(4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfa...)
Show SMILES CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C13H19NO4S/c1-3-9-14(10-4-2)19(17,18)12-7-5-11(6-8-12)13(15)16/h5-8H,3-4,9-10H2,1-2H3,(H,15,16)
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n/an/a 8.64E+4n/an/an/an/an/an/a



University of Colorado Anschutz Medical Campus

Curated by ChEMBL


Assay Description
Inhibition of human URAT1 expressed in xenopus oocyte assessed as inhibition of [14C]-labelled urate uptake after 60 mins by liquid scintillation cou...

J Med Chem 54: 2701-13 (2011)


Article DOI: 10.1021/jm1015022
BindingDB Entry DOI: 10.7270/Q2P26ZDR
More data for this
Ligand-Target Pair
Solute carrier family 22 member 7


(Homo sapiens (Human))		BDBM50390999
PNG
(CEFOPERAZONE)
Show SMILES CCN1CCN(C(=O)N[C@@H](C(=O)N[C@H]2[C@H]3SCC(CSc4nnnn4C)=C(N3C2=O)C(O)=O)c2ccc(O)cc2)C(=O)C1=O |c:26|
Show InChI InChI=1S/C25H27N9O8S2/c1-3-32-8-9-33(21(39)20(32)38)24(42)27-15(12-4-6-14(35)7-5-12)18(36)26-16-19(37)34-17(23(40)41)13(10-43-22(16)34)11-44-25-28-29-30-31(25)2/h4-7,15-16,22,35H,3,8-11H2,1-2H3,(H,26,36)(H,27,42)(H,40,41)/t15-,16-,22-/m1/s1
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n/an/a 1.33E+6n/an/an/an/an/an/a



Kyorin University School of Medicine

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of PGF2alpha in OAT2-S2 cells

Eur J Pharmacol 465: 1-7 (2003)


BindingDB Entry DOI: 10.7270/Q2CC11SX
More data for this
Ligand-Target Pair
Solute carrier family 22 member 7


(Homo sapiens (Human))		BDBM82898
PNG
((6R,7R)-3-(acetoxymethyl)-8-keto-7-[[2-(2-thienyl)...)
Show SMILES CC(=O)OCC1=C(N2[C@H](SC1)[C@H](NC(=O)Cc1cccs1)C2=O)C(O)=O |t:5|
Show InChI InChI=1S/C16H16N2O6S2/c1-8(19)24-6-9-7-26-15-12(14(21)18(15)13(9)16(22)23)17-11(20)5-10-3-2-4-25-10/h2-4,12,15H,5-7H2,1H3,(H,17,20)(H,22,23)/t12-,15-/m1/s1
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n/an/a 1.41E+6n/an/an/an/an/an/a



Kyorin University School of Medicine

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of PGF2alpha in OAT2-S2 cells

Eur J Pharmacol 465: 1-7 (2003)


BindingDB Entry DOI: 10.7270/Q2CC11SX
More data for this
Ligand-Target Pair
Solute carrier family 22 member 7


(Rattus norvegicus)		BDBM82898
PNG
((6R,7R)-3-(acetoxymethyl)-8-keto-7-[[2-(2-thienyl)...)
Show SMILES CC(=O)OCC1=C(N2[C@H](SC1)[C@H](NC(=O)Cc1cccs1)C2=O)C(O)=O |t:5|
Show InChI InChI=1S/C16H16N2O6S2/c1-8(19)24-6-9-7-26-15-12(14(21)18(15)13(9)16(22)23)17-11(20)5-10-3-2-4-25-10/h2-4,12,15H,5-7H2,1H3,(H,17,20)(H,22,23)/t12-,15-/m1/s1
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n/an/a 1.50E+6n/an/an/an/an/an/a



Kyorin University School of Medicine

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of PGF2alpha in OAT2-S2 cells

Eur J Pharmacol 465: 1-7 (2003)


BindingDB Entry DOI: 10.7270/Q2CC11SX
More data for this
Ligand-Target Pair
Solute carrier family 22 member 7


(Homo sapiens (Human))		BDBM50350468
PNG
(CEFAMANDOLE)
Show SMILES Cn1nnnc1SCC1=C(N2[C@H](SC1)[C@H](NC(=O)[C@H](O)c1ccccc1)C2=O)C(O)=O |r,t:9|
Show InChI InChI=1S/C18H18N6O5S2/c1-23-18(20-21-22-23)31-8-10-7-30-16-11(15(27)24(16)12(10)17(28)29)19-14(26)13(25)9-5-3-2-4-6-9/h2-6,11,13,16,25H,7-8H2,1H3,(H,19,26)(H,28,29)/t11-,13-,16-/m1/s1
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n/an/a 1.57E+6n/an/an/an/an/an/a



Kyorin University School of Medicine

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of PGF2alpha in OAT2-S2 cells

Eur J Pharmacol 465: 1-7 (2003)


BindingDB Entry DOI: 10.7270/Q2CC11SX
More data for this
Ligand-Target Pair
Solute carrier family 22 member 7


(Rattus norvegicus)		BDBM50390999
PNG
(CEFOPERAZONE)
Show SMILES CCN1CCN(C(=O)N[C@@H](C(=O)N[C@H]2[C@H]3SCC(CSc4nnnn4C)=C(N3C2=O)C(O)=O)c2ccc(O)cc2)C(=O)C1=O |c:26|
Show InChI InChI=1S/C25H27N9O8S2/c1-3-32-8-9-33(21(39)20(32)38)24(42)27-15(12-4-6-14(35)7-5-12)18(36)26-16-19(37)34-17(23(40)41)13(10-43-22(16)34)11-44-25-28-29-30-31(25)2/h4-7,15-16,22,35H,3,8-11H2,1-2H3,(H,26,36)(H,27,42)(H,40,41)/t15-,16-,22-/m1/s1
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n/an/a 1.62E+6n/an/an/an/an/an/a



Kyorin University School of Medicine

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of PGF2alpha in OAT2-S2 cells

Eur J Pharmacol 465: 1-7 (2003)


BindingDB Entry DOI: 10.7270/Q2CC11SX
More data for this
Ligand-Target Pair
Solute carrier family 22 member 7


(Rattus norvegicus)		BDBM50350468
PNG
(CEFAMANDOLE)
Show SMILES Cn1nnnc1SCC1=C(N2[C@H](SC1)[C@H](NC(=O)[C@H](O)c1ccccc1)C2=O)C(O)=O |r,t:9|
Show InChI InChI=1S/C18H18N6O5S2/c1-23-18(20-21-22-23)31-8-10-7-30-16-11(15(27)24(16)12(10)17(28)29)19-14(26)13(25)9-5-3-2-4-6-9/h2-6,11,13,16,25H,7-8H2,1H3,(H,19,26)(H,28,29)/t11-,13-,16-/m1/s1
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n/an/a 3.18E+6n/an/an/an/an/an/a



Kyorin University School of Medicine

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of PGF2alpha in OAT2-S2 cells

Eur J Pharmacol 465: 1-7 (2003)


BindingDB Entry DOI: 10.7270/Q2CC11SX
More data for this
Ligand-Target Pair
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