| Reaction Details |
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 | Report a problem with these data |
| Target | Kallikrein-5 [D153N] |
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| Ligand | BDBM50391077 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_840619 (CHEMBL2090270) |
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| IC50 | 323500±n/a nM |
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| Citation |  Freitas, RF; Teixeira, TS; Barros, TG; Santos, JA; Kondo, MY; Juliano, MA; Juliano, L; Blaber, M; Antunes, OA; Abrahão, O; Pinheiro, S; Muri, EM; Puzer, L Isomannide derivatives as new class of inhibitors for human kallikrein 7. Bioorg Med Chem Lett22:6072-5 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Kallikrein-5 [D153N] |
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| Name: | Kallikrein-5 [D153N] |
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| Synonyms: | KLK-L2 | KLK5 | KLK5_HUMAN | Kallikrein 5 | Kallikrein-5 | Kallikrein-like protein 2 | SCTE | Stratum corneum tryptic enzyme |
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| Type: | PROTEIN |
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| Mol. Mass.: | 32031.75 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1282456 |
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| Residue: | 293 |
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| Sequence: | MATARPPWMWVLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARS
DDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGH
YSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNNLMLIKLNRRIRPTKDVRPINVSSHCPS
AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDS
CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS
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| BDBM50391077 |
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| n/a |
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| Name | BDBM50391077 |
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| Synonyms: | CHEMBL2087345 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H27N3O5 |
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| Mol. Mass. | 485.5311 |
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| SMILES | O=C(N[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1)C(\NC(=O)c1ccccc1)=C\c1cccnc1 |r| |
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| Structure | 
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