| Reaction Details |
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 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M2 |
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| Ligand | BDBM50347782 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_849488 (CHEMBL2149595) |
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| EC50 | >25118.86±n/a nM |
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| Citation |  Budzik, B; Garzya, V; Shi, D; Walker, G; Woolley-Roberts, M; Pardoe, J; Lucas, A; Tehan, B; Rivero, RA; Langmead, CJ; Watson, J; Wu, Z; Forbes, IT; Jin, J Novel N-Substituted Benzimidazolones as Potent, Selective, CNS-Penetrant, and Orally Active M1 mAChR Agonists. ACS Med Chem Lett1:244-248 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Muscarinic acetylcholine receptor M2 |
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| Name: | Muscarinic acetylcholine receptor M2 |
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| Synonyms: | ACM2_HUMAN | CHRM2 | Cholinergic, muscarinic M2 | Muscarinic acetylcholine receptor M2 and M4 | Muscarinic acetylcholine receptor M2 and M5 | RecName: Full=Muscarinic acetylcholine receptor M2 |
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| Type: | GPCR |
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| Mol. Mass.: | 51730.61 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P08172 |
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| Residue: | 466 |
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| Sequence: | MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI
VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE
ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI
VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
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| BDBM50347782 |
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| n/a |
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| Name | BDBM50347782 |
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| Synonyms: | CHEMBL1802360 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H24FN3O2 |
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| Mol. Mass. | 369.4326 |
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| SMILES | Fc1ccc(OCCCN2CCC(CC2)n2c3ccccc3[nH]c2=O)cc1 |
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| Structure | 
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