| Reaction Details |
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 | Report a problem with these data |
| Target | Cathepsin K |
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| Ligand | BDBM50392212 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_852643 (CHEMBL2157192) |
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| Ki | >4000±n/a nM |
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| Citation |  Frizler, M; Schmitz, J; Schulz-Fincke, AC; Gütschow, M Selective nitrile inhibitors to modulate the proteolytic synergism of cathepsins S and F. J Med Chem55:5982-6 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cathepsin K |
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| Name: | Cathepsin K |
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| Synonyms: | CATK_HUMAN | CTSK | CTSO | CTSO2 | Cathepsin O | Cathepsin O2 | Cathepsin X |
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| Type: | Enzyme |
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| Mol. Mass.: | 36975.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P43235 |
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| Residue: | 329 |
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| Sequence: | MWGLKVLLLPVVSFALYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIH
NLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVD
YRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGG
YMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVA
RVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGE
NWGNKGYILMARNKNNACGIANLASFPKM
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| BDBM50392212 |
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| n/a |
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| Name | BDBM50392212 |
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| Synonyms: | CHEMBL2153165 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H23N3O4S2 |
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| Mol. Mass. | 433.544 |
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| SMILES | CC(C)CS(=O)(=O)CC(NC(=O)c1cc(cs1)-c1ccccc1)C(=O)NCC#N |
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| Structure | 
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