| Reaction Details |
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 | Report a problem with these data |
| Target | Fatty-acid amide hydrolase 1 |
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| Ligand | BDBM50394380 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_854554 (CHEMBL2161049) |
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| IC50 | 27542±n/a nM |
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| Citation |  Morera, L; Labar, G; Ortar, G; Lambert, DM Development and characterization of endocannabinoid hydrolases FAAH and MAGL inhibitors bearing a benzotriazol-1-yl carboxamide scaffold. Bioorg Med Chem20:6260-75 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Fatty-acid amide hydrolase 1 |
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| Name: | Fatty-acid amide hydrolase 1 |
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| Synonyms: | Anandamide amidohydrolase | Anandamide amidohydrolase 1 | FAAH | FAAH1 | FAAH1_HUMAN | Fatty Acid Amide Hydrolase (FAAH) | Fatty-acid amide hydrolase (FAAH) | Fatty-acid amide hydrolase 1 | Oleamide hydrolase 1 |
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| Type: | Protein |
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| Mol. Mass.: | 63071.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O00519 |
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| Residue: | 579 |
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| Sequence: | MVQYELWAALPGASGVALACCFVAAAVALRWSGRRTARGAVVRARQRQRAGLENMDRAAQ
RFRLQNPDLDSEALLALPLPQLVQKLHSRELAPEAVLFTYVGKAWEVNKGTNCVTSYLAD
CETQLSQAPRQGLLYGVPVSLKECFTYKGQDSTLGLSLNEGVPAECDSVVVHVLKLQGAV
PFVHTNVPQSMFSYDCSNPLFGQTVNPWKSSKSPGGSSGGEGALIGSGGSPLGLGTDIGG
SIRFPSSFCGICGLKPTGNRLSKSGLKGCVYGQEAVRLSVGPMARDVESLALCLRALLCE
DMFRLDPTVPPLPFREEVYTSSQPLRVGYYETDNYTMPSPAMRRAVLETKQSLEAAGHTL
VPFLPSNIPHALETLSTGGLFSDGGHTFLQNFKGDFVDPCLGDLVSILKLPQWLKGLLAF
LVKPLLPRLSAFLSNMKSRSAGKLWELQHEIEVYRKTVIAQWRALDLDVVLTPMLAPALD
LNAPGRATGAVSYTMLYNCLDFPAGVVPVTTVTAEDEAQMEHYRGYFGDIWDKMLQKGMK
KSVGLPVAVQCVALPWQEELCLRFMREVERLMTPEKQSS
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| BDBM50394380 |
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| n/a |
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| Name | BDBM50394380 |
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| Synonyms: | CHEMBL2159807 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H19N5O3 |
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| Mol. Mass. | 365.3859 |
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| SMILES | OC(=O)c1cccc(CN2CCN(CC2)C(=O)n2nnc3ccccc23)c1 |
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| Structure | 
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