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TargetAcetylcholine Binding protein
LigandBDBM50382466
Substrate/Competitorn/a
Meas. Tech.ChEMBL_874929
Ki 12.8±n/a nM
Citation Zhang HKEaton JBYu LFNys MMazzolari Avan Elk RSmit ABAlexandrov VHanania TSabath EFedolak ABrunner DLukas RJVistoli GUlens CKozikowski AP Insights into the structural determinants required for high-affinity binding of chiral cyclopropane-containing ligands toa4ß2-nicotinic acetylcholine receptors: an integrated approach to behaviorally active nicotinic ligands. J Med Chem 55:8028-37 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Acetylcholine Binding protein
Name:Acetylcholine Binding protein
Synonyms:ACh-binding protein | Acetylcholine-binding protein | Acetylcholine-binding protein (AchBP) | Acetylcholine-binding protein (Ls-AchBP) | AchBP
Type:n/a
Mol. Mass.:26055.52
Organism:Lymnaea stagnalis
Description:Soluble acetylcholine receptor
Residue:229
Sequence:
MRRNIFCLACLWIVQACLSLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEV
NEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQ
LARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDD
SEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRSEIL
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  Blast E-value cutoff:
BDBM50382466
n/a
NameBDBM50382466
Synonyms:CHEMBL2024087
TypeSmall organic molecule
Emp. Form.C14H20N2O2
Mol. Mass.248.3208
SMILESOCC[C@H]1C[C@@H]1c1cncc(OC[C@@H]2CCN2)c1 |r|
Structure
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