| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM50398947 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_875495 (CHEMBL2183136) |
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| Ki | 0.9±n/a nM |
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| Citation |  Moynihan, HA; Derrick, I; Broadbear, JH; Greedy, BM; Aceto, MD; Harris, LS; Purington, LC; Thomas, MP; Woods, JH; Traynor, JR; Husbands, SM; Lewis, JW Fumaroylamino-4,5-epoxymorphinans and related opioids with irreversibleµ opioid receptor antagonist effects. J Med Chem55:9868-74 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 11165.58 |
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| Organism: | GUINEA PIG |
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| Description: | P97266 |
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| Residue: | 98 |
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| Sequence: | YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSI
FTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
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|
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| BDBM50398947 |
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| n/a |
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| Name | BDBM50398947 |
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| Synonyms: | CHEMBL2179262 |
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| Type | Small organic molecule |
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| Emp. Form. | C32H36N2O4 |
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| Mol. Mass. | 512.6392 |
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| SMILES | CO[C@]12CC[C@@]3(C[C@@H]1NC(=O)\C=C\c1ccccc1)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CCN1CC1CC1)c45 |r,THB:8:7:29.28:3.4| |
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| Structure | 
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