| Reaction Details |
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 | Report a problem with these data |
| Target | Superoxide dismutase [Cu-Zn] |
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| Ligand | BDBM50398956 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_875514 (CHEMBL2183508) |
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| IC50 | 125320±n/a nM |
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| Citation |  Sánchez-Moreno, M; Gómez-Contreras, F; Navarro, P; Marín, C; Olmo, F; Yunta, MJ; Sanz, AM; Rosales, MJ; Cano, C; Campayo, L Phthalazine derivatives containing imidazole rings behave as Fe-SOD inhibitors and show remarkable anti-T. cruzi activity in immunodeficient-mouse mode of infection. J Med Chem55:9900-13 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Superoxide dismutase [Cu-Zn] |
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| Name: | Superoxide dismutase [Cu-Zn] |
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| Synonyms: | SOD1 | SODC_HUMAN | Superoxide dismutase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 15933.55 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1444880 |
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| Residue: | 154 |
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| Sequence: | MATKAVCVLKGDGPVQGIINFEQKESNGPVKVWGSIKGLTEGLHGFHVHEFGDNTAGCTS
AGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVADVSIEDSVISLSGDHCIIGRTLVV
HEKADDLGKGGNEESTKTGNAGSRLACGVIGIAQ
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| BDBM50398956 |
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| n/a |
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| Name | BDBM50398956 |
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| Synonyms: | CHEMBL2179267 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H20N8 |
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| Mol. Mass. | 348.405 |
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| SMILES | C(Cc1cnc[nH]1)Nc1nnc(NCCc2cnc[nH]2)c2ccccc12 |
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| Structure | 
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